The second messenger cyclic AMP with a methylated ribose 2'-hydroxyl group immobilized on agarose by an aminoethylthio spacer attached to position 8 of the ligand. Considered to be suitable for affinity chromatography of various cAMP-responsive proteins, especially those which tolerate modification of the ribose 2'-hydroxyl group, such as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases. Detailed technical information available.
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7).
Cat. No. | A 195 |
CAS number | [pending] |
Appearance | Suspension in 30 mM Na₂HPO₄ buffer (pH 7) |
Storage temperature | 4°C / 39°F |
Modifications | 8-cAMP, 2'-cAMP |