The second messenger cyclic AMP with a methylated ribose 2'-hydroxy group immobilized on agarose by an aminohexylamino spacer attached to position 8 of the ligand. Suitable for affinity chromatography of various cAMP-responsive proteins, especially those which tolerate modification of the ribose 2'-hydroxy group, such as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases. Detailed technical information available. Reference: Borland et al., Mol. Pharmacol., 69, 374 - 384 (2006).
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
|Cat. No.||A 057|
|Patent Information||The reagent is protected under patent EP 1511757 and foreign equivalents issued or licensed to BIOLOG Life Science Institute.|
|Storage temperature||4°C / 39°F|