8-AET-2'-O-Me-cAMP has only poor affinity towards protein kinases A and G and is thus suitable as a ligand in affinity chromatography of cAMP binding proteins that do not require an intact 2'-OH group, such as the exchange protein activated by cyclic AMP (Epac) and certain phosphodiesterases. Detailed technical information available. For reference please compare: Borland et al., Mol. Pharmacol., 69, 374 - 384 (2006).
|Cat. No.||A 142|
|Purity||> 98% HPLC|
|Storage temperature||-20°C / -4°F|
|Molecular formula||C₁₃H₁₈N₆O₆PS · Na|
|Molecular weight [g/mol]||440.4|
|Absorption max [nm]||279|
|Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]||17000|