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8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( 8-Br-2'-O-Me-cAMP-AM )
Metabolically activatable Epac agonist
Cat. No.: B 028
CAS No.: [pending]
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Cat. No.: B 028-01
Unit: 1 µmol / ~0.5 mg
Extremely membrane-permeant precursor of the specific Epac agonist 8-Br-2'-O-Me-cAMP (Cat. No. B 022). After permeation and metabolic activation by esterases the active compound is released. Detailed technical information available. Reference: Börner et al., Nature Protocols, 6, 427 - 438 (2011).
Biolog also offers Phosphate tris(acetoxymethyl)ester (PO4-AM3, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.
Cat. No. B 028
Patent Information Protected by patent n° EP 02077219.0 and foreign equivalents, exclusively licensed to BIOLOG LSI for research purposes only
CAS number [pending]
Purity > 97% HPLC for mixture of isomers
Storage temperature -20°C / -4°F
Molecular formula C₁₄H₁₇BrN₅O₈P
Molecular weight [g/mol] 494,2
Modifications 8-cAMP, 2'-cAMP
Absorption max [nm] 264
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000