The protein kinase A activator cyclic AMP immobilized on agarose by an aminoethylcarbamoyl spacer attached to the ribose 2'-position of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'-ribose hydroxyl group such as some phosphodiesterases. This type of gel is also offered with a longer spacer (2'-AHC-cAMP-Agarose, Cat. No. A 058) and as a PDE-resistant version (Rp- & Sp-2'-AEC-cAMPS-Agarose, Cat. No. A 126 & A 122). Detailed technical information available.
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7).
|Cat. No.||A 112|
|Appearance||Suspension in 30 mM Na₂HPO₄ buffer (pH 7)|
|Storage temperature||4°C / 39°F|