The protein kinase A activator cyclic AMP immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2'-position of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'-ribose hydroxyl group such as some phosphodiesterases. This type of gel is also offered with a shorter spacer (2'-AEC-cAMP-Agarose, Cat. No. A 112) and as PDE-resistant version (Sp-2'-AHC-cAMPS-Agarose, Cat. No. A 050). Detailed technical information available.
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7).
|Cat. No.||A 058|
|Appearance||Suspension in 30 mM Na₂HPO₄ buffer (pH 7)|
|Storage temperature||4°C / 39°F|