The protein kinase G activator cyclic GMP immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2'-position of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'-ribose hydroxyl group, such as some phosphodiesterases. This type of gel is offered as PDE-resistant version (Sp-2'-AHC-cGMPS-Agarose, Cat. No. A 052) as well. Detailed technical information available. References: Kim & Park, J. Niochem. Mol. Biol., 36, 299-304 (2003); Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7).
|Cat. No.||A 059|
|Appearance||Suspension in 30 mM Na₂HPO₄ buffer (pH 7)|
|Storage temperature||4°C / 39°F|