0 Items - $0.00
Categories
A to Z

8-Br-cAMP-AM

8- Bromoadenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( 8-Br-cAMP-AM )
Metabolically activatable prodrug of the PKA agonist 8-Br-cAMP
Cat. No.: B 020
    
CAS No.: [190522-24-8]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: B 020-01
Unit: 1 µmol / ~0.5 mg
$139.00
Highly membrane-permeant precursor of the PKA activator 8-Br-cAMP (Cat. No. B 007). Metabolic activation by esterases releases the polar active analogue, which is trapped inside the cell. Detailed technical information available. References: Kruppa et al., Bioorg. Med. Chem. Lett., 7, 945 - 948 (1997); Krakstad et al., J. Leukocyte Biol., 76, 641 - 647 (2004); Moll et al., J. Neural. Transm., 113, 1015 - 1032 (2006).
Biolog also offers Phosphate tris(acetoxymethyl)ester (PO4-AM3, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.
Cat. No. B 020
CAS number [190522-24-8]
Purity > 97% HPLC for mixture of isomers
Storage temperature -20°C / -4°F
Molecular formula C₁₃H₁₅BrN₅O₈P
Molecular weight [g/mol] 480,2
Modifications 8-cAMP
Target PKA (cAK) Activator
Absorption max [nm] 264
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000