Basket (0 Items) - Amount: 0.00$Phosphate tris(acetoxymethyl)ester ( PO4-AM3 )
Control reagent for nucleotide-AM ester applications
Cat. No.: P 030 CAS No.: [pending]
C9H15O10P; MW 314.2; purity > 95% (MS). Membrane-permeant prodrug of inorganic phosphate. After permeation and metabolic activation by esterases the highly polar inorganic phosphate (PO43-) is released. In addition, the AM ester groups liberate acetic acid and formaldehyde, two metabolites with potential biological functions. Therefore, PO4-AM3 is recommended as control reagent in nucleotide-AM ester applications to test for side effects of acetic acid and formaldehyde. References: Chepurny et al., J. Biol. Chem., 284, 10728 - 10736 (2009); Schultz et al., J. Biol. Chem., 268, 6316 - 6322 (1993).
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