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8-Br-cAMP

8- Bromoadenosine- 3', 5'- cyclic monophosphate ( 8-Br-cAMP ), sodium salt
Fluorescence grade
Cat. No.: B 007
    
CAS No.: [76939-46-3]
Technical Information
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: B 007-100
Unit: 100 µmol / ~43 mg
$62.00
bulk request
Highly purified, typical fluorescent impurities removed. For other salt forms or metabolites of 8-Br-cAMP please inquire. Activator of cAMP-dependent protein kinase and of Epac. Increased hydrolytical stability and membrane permeability compared to cAMP. Detailed technical information and selected references available. Reference: Kroeber et al., J. Neurochem., 74, 2478 - 2489 (2000).
Cat. No. B 007
CAS number [76939-46-3]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₀BrN₅O₆P · Na
Molecular weight [g/mol] 430.1
Modifications 8-cAMP
Target PKA (cAK) Activator
Lipophilicity 1.35
Absorption max [nm] 264
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000
  • 1. Schwede F., Bertinetti D., Langerijs C. N., Hadders M. A., Wienk H., Ellenbroek J. H., de Koning E. J. P., Bos J. L., Herberg F. W., Genieser H.-G., Janssen R. A.Rehmann H., PLoS Biol., 13, 1 - 26 (2015), "Structure-Guided Design of Selective Epac1 and Epac2 Agonists"
  • 2. Jäger R., Russwurm C., Schwede F., Genieser H.-G., Koesling D.Russwurm M., J. Biol. Chem., 287, 1210 - 1219 (2012), "Activation of PDE10 and PDE11 Phosphodiesterases"
  • 3. Chen Z.-H.Schaap P., Nature, 488, 680 - 683 (2012), "The Prokaryote Messenger c-di-GMP Triggers Stalk Cell Differentiation in Dictyostelium"
  • 4. Jennissen K., Siegel F., Liebig-Gonglach M., Hermann M.-R., Kipschull S., van Dooren S., Kunz W. S., Fässler R.Pfeifer A., Sci. Signal., 5, 0 - 0 (2012), "A VASP-Rac-Soluble Guanylyl Cyclase Pathway Controls cGMP Production in Adipocytes"
  • 5. Werner K., Schwede F., Genieser H.-G., Geiger J.Butt E., Naunyn Schmiedebergs Arch. Pharmacol., 384, 169 - 176 (2011), "Quantification of cAMP and cGMP Analogs in Intact Cells: Pitfalls in Enzyme Immunoassays for Cyclic Nucleotides"
  • 6. Enyeart J. A., Liu H.Enyeart J. J., Am. J. Physiol. Endocrinol. Metab., 301, 941 - 954 (2011), "8-Phenylthio-adenines Stimulate the Expression of Steroid Hydroxylases, Cav3.2 Ca2+ Channels, and Cortisol Synthesis by a cAMP-independent Mechanism"
  • 7. Liu H., Enyeart J. J.Enyeart J. A., J. Biol. Chem., 285, 20040 - 20050 (2010), "ACTH Induces CAv3.2. Current and mRNA by cAMP-dependent and cAMP-independent Mechanism"
  • 8. Eijkelkamp N., Wang H. J., Garza-Carbajal A., Willemen H. L. D. M., Zwartkruis F. J., Wood J. N., Dantzer R., Kelley K. W., Heijnen C. J.Kavelaars A., J. Neurosci., 30, 12806 - 12815 (2010), "Low Nociceptor GRK2 Prolongs Prostaglandin E-2 Hyperalgesia via Biased cAMP Signaling to epac/Rap1, Protein Kinase C Epsilon, and MEK/ERK"
  • 9. Grandoch M., de Jesus B. M., Oude Weernink P. A., Weber A. A., Jakobs K. H.Schmidt M., Cell Signal, 4, 609 - 621 (2009), "B Cell Receptor-induced Growth Arrest and Apoptosis in WEHI-231 Immature B Lymphoma Cells Involve Cyclic AMP and Epac Proteins"
  • 10. Voisin P.Bernard M., J. Neurochem., 110, 318 - 327 (2009), "Cyclic AMP-dependent Activation of Rhodopsin Gene Transcription in Cultured Retinal Precursor Cells of Chicken Embryo"
  • 11. Zhang C.-L., Katoh M., Shibasaki T., Minami K., Sunaga Y., Takahashi H., Yokoi N., Iwasaki M., Miki T.Seino S., Science, 325, 607 - 610 (2009), "The cAMP Sensor Epac2 Is a Direct Target of Antidiabetic Sulfonylurea Drugs"
  • 12. Bastian P., Balcarek A., Altanis C., Strell C., Niggemann B., Zänker K. S.Entschladen F., Cancer Lett., 274, 1218 - 1234 (2009), "The Inhibitory Effect of Norepinephrine on the Migration of ES-2 Ovarian Carcinoma Cells Involves a Rap1-dependent Pathway"
  • 13. Waidmann O., Pleli T., Dvorak K., Baehr C., Mondorf U., Plotz G., Biondi R. M., Zeuzem S.Piiper A., J.Biol.Chem., 284, 32256 - 32263 (2009), "Inhibition of the Equilibrative Nucleoside Transporter 1 and Activation of A2A Adenosine Receptors by 8-(4-Chlorophenylthio)-modified cAMP Analogs and their Hydrolytic Products"
  • 14. Matthiesen K.Nielsen J., Biochem. J., 423, 401 - 409 (2009), "Binding of Cyclic Nucleotides to Phosphodiesterase 10A and 11A GAF Domains Does Not Stimulate Catalytic Activity"
  • 15. Carmona G., Chavakis E., Koehl U., Zeiher A. M.Dimmeler S., Blood, 111, 2640 - 2646 (2008), "Activation of Epac Stimulates Integrin-dependent Homing of Progenitor Cells"
  • 16. Schweinsberg S., Moll D., Burghardt N. C., Hahnefeld C., Schwede F., Zimmermann B., Drewianka S., Werner L., Kleinjung F., Genieser H.-G., Schuchhardt J.Herberg F. W., Proteomics, 8, 1212 - 1220 (2008), "Systematic interpretation of cyclic nucleotide binding studies using KinetXBase"
  • 17. Shah A. U., Grant W. M., Latif S. U., Mannan Z. M., Park A. J.Husain S. Z., Am. J. Phys. Gastro. Liver Phys., 294, 1328 - 1334 (2008), "Cyclic-AMP Accelerates Calcium Waves in Pancreatic Acinar Cells"
  • 18. Poppe H., Rybalkin S. D., Rehmann H., Hinds T. R., Tang X.-B., Christensen A. E., Schwede F., Genieser H.-G., Bos J. L., Doeskeland S. O., Beavo J. A.Butt E., Nature Methods, 5, 277 - 278 (2008), "Cyclic Nucleotide Analogs as Probes of Signaling Pathways"
  • 19. Lyle K. S., Raaijmakers J. H., Bruinsma W., Bos J. L.de Rooij J., Cell. Signal., 20, 1104 - 1116 (2008), "cAMP-induced Epac-Rap Activation Inhibits Epithelial Cell Migration by Modulating Focal Adhesion and Leading Edge Dynamics"
  • 20. Haag S., Warnken M., Juergens U. R.Racke K., Naunyn-Schmiedeberg's Arch. Pharmacol., 378, 617 - 630 (2008), "Role of Epac1 in Mediating Anti-proliferative Effects of Prostanoid EP2 Receptors and cAMP in Human Lung Fibroblasts"
  • 21. Brock M., Fan F., Mei F. C., Li S., Gessner C., Woods V. L.Cheng X. D., J. Biol. Chem., 282, 32256 - 32263 (2007), "Confirmational Analysis of Epac Activation Using Amide Hydrogen/Deuterium Exchange Mass Spectrometry"
  • 22. Murtazina R., Kovbasnjuk O., Zachos N. C., Li X., Chen Y., Hubbard A., Hogema B. M., Steplock D., Seidler U., Hoque K. M., Tse C. M., De Jonge H. R., Weinmann E. J.Donowitz M., J. Biol. Chem., 282, 25141 - 25151 (2007), "Tissue Specific Regulation of Sodium-Proton Exchanger Isoform 3 (NHE3) Activity in Na/H Exchanger Regulatory Factor 1 (NHERF1) Null Mice: cAMP Inhibition is Differentially Dependent on NHERF1 and Exchange Protein Directly Activated by cAMP (EPAC)Ileum Versus Proximal Tubule"
  • 23. Jiang L. I., Collins J., Davis R., Lin K.-M., DeCamp D., Roach T., Hsueh R., Rebres R. A., Ross E. M., Taussig R., Fraser I.Sternweis P. C., J. Biol. Chem., 282, 10576 - 10584 (2007), "Use of a cAMP BRET Sensor to Characterize a Novel Regulation of cAMP by the Sphingosine-1-phosphate/G13 Pathway"
  • 24. Shibasaki T., Takahashi H., Miki M., Sunaga Y., Matsumura K., Yamanaka M., Zhang C., Tamamoto A., Satoh T., Miyazaki J.-I.Seino S., PNAS, 104, 19333 - 19338 (2007), "Essential Role of Epac2/Rap1 Signaling in Regulation of Insulin Granule Dynamics by cAMP"
  • 25. Broderick K. E., Zhang T., Rangaswami H., Zeng Y., Zhao X., Boss G. R.Pilz R. B., Mol. Endocrinol., 21, 1148 - 1162 (2007), "Guanosine 3',5'-cyclic monophosphate (cGMP)/cGMP-dependent Protein Kinase Induce Interleukin-6 Transcription in Osteoblasts"
  • 26. Bos J. L., Trends Biochem. Sci., 31, 680 - 686 (2006), "Epac Proteins: Multi-purpose cAMP Targets"
  • 27. Petralia S. M.Frye C. A., J. Endocrinol., 18, 902 - 914 (2006), "In the Ventral Tegmental Area, Cyclic AMP Mediates the Actions of Progesterone at Dopamine Type1 Receptors for Lordosis of Rats and Hamsters"
  • 28. Makranz C., Cohen G., Reichert F., Kodama T.Rotshenker S., Glia., 53, 441 - 448 (2006), "cAMP Cascade (PKA, Epac, Adenylyl Cyclase, Gi, and Phosphodiesterases) Regulates Myelin Phagocytosis Mediated by Complement Receptor-3 and Scavenger Receptor-AI/II in Microglia amd Macrophages"
  • 29. Honegger K. J., Capuano P., Winter C., Bacic D., Stange G., Wagner C. A., Biber J., Murer H.Hernando N., Proc. Natl. Acad. Sci., 103, 803 - 808 (2006), "Regulation of Sodium-proton Exchanger Isoform 3 (NHE3) by PKA and Exchange Protein Directly Activated by cAMP (EPAC)"
  • 30. Dao K. K., Teigen K., Kopperud R. K., Hodneland E., Schwede F., Christensen A. E., Martinez A.Doeskeland S. O., J. Biol. Chem., 281, 21500 - 21511 (2006), "Epac1 and cAMP-dependent Protein Kinase Holoenzyme Have Similar cAMP Affinity, but Their cAMP Domains Have Distinct Structural Features and Cyclic Nucleotide Recognition"
  • 31. Gonzalez-Iglesias A. E., Jiang Y., Tomic M., Kretschmannova K., Andric S. A., Zemkova H.Stojilkovic S. S., Mol. Endocrinol., 20, 2231 - 2246 (2006), "Dependence of Electrical Activity and Calcium Influx-controlled Prolactin Release on Adenylyl Cyclase Signaling Pathway in Pituitary Lactotrophs"
  • 32. De Jesus M. L., Stope M. B., Oude Weernink P. A., Mahlke Y., Börgermann C., Ananba V. N., Rimmbach C., Rosskopf D., Michel M. C., Jakobs K. H.Schmidt M., J. Biol. Chem. 21837 21847, 281, 21837 - 21847 (2006), "Cyclic-AMP-dependent and Epac-mediated Activation of R-Ras by G Protein-coupled Receptors Leads to Phospholipase D Stimulation"
  • 33. Lotfi S., Li Z., Sun J., Zuo Y., Lamm P. P., Kang Y., Rahimi M., Islam D., Wang P., Gaisano H. Y.Jin T., Endocrinology, 147, 3727 - 3736 (2006), "Role of Excange Protein Directly Activated by cyclic Adenosine 5'-monophosphate (Epac) Pathway in Regulating Proglucagon Gene Expression in Intestinal Endocrine L Cells"
  • 34. Moll D., Prinz A., Gesellchen F., Drewianka S., Zimmermann B.Herberg F. W., J. Neural. Transm., 113, 1015 - 1032 (2006), "Biomolecular Interaction Analysis in Functional Proteomics"
  • 35. Meves H., Curr. Neuropharmacol., 4, 41 - 57 (2006), "The Action of Prostaglandins in Ion Channels"
  • 36. Shi G.-X., Rehmann H.Andres D. A., Mol. Cell. Biol., 26, 9136 - 9147 (2006), "A Novel cAMP-dependent Epac-Rit Signaling Pathway Contributes to PACAP38-mediated Neuronal Differentiation"
  • 37. McQuaid T. S., Saleh M. C., Joseph J. W., Gyulkhandanyan A., Manning-Fox J. E., MacLellan J. D., Wheeler M. B.Chan C. B., J. Endocrinol., 190, 669 - 680 (2006), "cAMP-mediated Signaling Normalizes Glucose-stimulated Insulin Secretion in Uncoupling Protein-2 Overexpressing {beta}-cells"
  • 38. Zhao C. N., Lai J. S., Warsh J. J.Li P. P., J. Neurosci. Res., 84, 389 - 397 (2006), "G alpha(s) Sensitizes Human SH-SY5Y Cells to Apoptosis Independently of the Protein Kinase A Pathway"
  • 39. Cytrynska M., Zdybicka-Barabas A.Jakubowicz T., J. Insect Physiol., 52, 744 - 753 (2006), "Studies on the Role of Protein Kinase A in Humoral Immune Response of Galleria Mellonella Larvae"
  • 40. Müller D., Cortes-Dericks L., Budnik L. T., Brunswig-Spickenheier B., Pancratius M., Speth R. C., Mukhopadhyay A. K.Middendorff R., Endocrinology, 147, 2974 - 2985 (2006), "Homologous and Lysophosphatidic Acid-induced Desensitization of the Atrial Natriuretic Peptide Receptor, Guanylyl Cyclase-A, in MA-10 Leydig Cells"
  • 41. Liu G. H., Jacobo S. M. P., Hilliard N.Hockerman G. H., J. Pharmacol. Exp. Ther., 318, 152 - 160 (2006), "Differential Modulation of Ca(v)1.2 and Ca(v)1.3-Mediated Glucose-Stimulated Insulin Secretion by cAMP in INS-1 Cells: Distinct Roles for Exchange Protein Directly Activated by cAMP 2 (Epac2) and Protein Kinase A"
  • 42. Woolcock K.Specht S. C., Life Sci., 78, 1653 - 1661 (2006), "Modulation of Na, K-ATPase Activity by Prostaglandin E-1 and [D-Ala(2),N-Me-Phe(4)GlY(5)-ol]-enkephalin"
  • 43. Holz G. G., Kang G., Harbeck M., Roe M. W.Chepurny O. G., J. Physiol.- London, 577, 5 - 15 (2006), "Cell Physiology of cAMP Sensor Epac"
  • 44. Aronoff D. M., Canetti C., Serezani C. H., Luo M.Peters-Golden M., J. Immunology, 174, 595 - 599 (2005), "Cutting Edge: Macrophage Inhibition by cyclic AMP (cAMP): Differential Roles of Protein Kinase A and Exchange Protein Directly Activated by cAMP-1"
  • 45. Johnson-Farley N. N., Kertesy S. B., Dubyak G. R.Cowen D. S., J. Neurochem., 92, 72 - 82 (2005), "Enhanced Activation of Akt and Extracellular-regulated Kinase Pathways by Simultaneous Occupancy of Gq-coupled 5-HT2A Receptors and Gs-coupled 5-HT7A Receptors in PC12 Cells"
  • 46. Moon E. Y., Oh S. Y., Han G. H., Lee C. S.Park S. K., J. Neurosci. Res., 81, 38 - 44 (2005), "Epac1-mediated Rap1 Activation is Not Required for the Production of Nitric Oxide in BV2, Murine Microglial Cells"
  • 47. Persson E., Voznesensky O. S., Huang Y. F.Lerner U. H., Bone, 37, 513 - 529 (2005), "Increased Expression of Interleukin-6 by Vasoactive Intestinal Peptide is Associated with Regulation of CREB, AP-1 and C/EBP, but not NF-kappa B, in Mouse Calvarial Osteoblasts"
  • 48. Keung W., Vanhoutte P. M.Man R. Y. K., Brit. J. Pharmacol., 144, 71 - 79 (2005), "Acute Impairment of Contractile Responses by 17-Beta-estradiol is cAMP and Protein Kinase G Dependent in Vascular Smooth Muscle Cells of the Porcine Coronary Arteries"
  • 49. Ohno F., Watanabe J., Sekihara H., Hirabashi T., Arata S., Kikuyama S., Shioda S., Nakaya K.Nakajo S., Regul. Pept., 126, 115 - 122 (2005), "Pituitary Adenylate Cyclase-activating Polypeptide Promotes Differentiation of Mouse Neural Stem Cells into Astrocytes"
  • 50. Jao Y., Hiramatsu N., Zhu Y., Morioka T., Takeda M., Oite T.Kitamura M., J. Am. Soc. Nephrol., 16, 58 - 67 (2005), "Nitric Oxide-mediated Regulation of Connexin43 Expression and Gap Junctional Intercellular Communication in Mesangial Cells"
  • 51. Amsen E. M., Pham N., Pak Y.Rotin D., J. Biol. Chem., 281, 121 - 128 (2005), "The Guanine Nucleotide Excange Factor CNrasGEF Regulates Melanogenesis and Cell Survival in Melanoma Cells"
  • 52. Borba J. C., Henze I. P., Silveira M. S., Kubrusly R. C., Gardino P. F., de Mello M. C. F., Hokoc J. N.de Mello F. G., Develop. Brain Res., 156, 193 - 201 (2005), "Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) can Act as Determinant of the Tyrosine Hydroxylase Phenotype of Dopaminergic Cells During Retina Development"
  • 53. Gao Y. S., Dhanakoti S., Trevino E. M., Wang X. H., Sander F. C., Portugal A. D.Raj J. U., Am. J. Physiol.-Lung Cell Mol. Physiol., 286, 786 - 792 (2004), "Role of cGMP-dependent Protein Kinase in Development of Tolerance to Nitric Oxide in Pulmonary Veins of Newborn Lambs"
  • 54. Tiwari S., Felekkis K., Moon E. Y., Flies A., Sherr D. H.Lerner A., Blood, 103, 2661 - 2667 (2004), "Among Circulating Hematopoietic Cells, B-CLL Uniquely Expresses Functional EPAC1 but EPAC1-mediated Rap1 Activation does not Account for PDE4 Inhibitor-induced Apoptosis"
  • 55. Shih A., Zhang S., Cao H. J., Tang H. Y., Davis F. B., Davis P. J.Lin H. Y., Endocrinology, 145, 1708 - 1717 (2004), "Disparate Effects of Thyroid Hormone on Actions of Epidermal Growth factor and Transforming Growth Factor-alpha are Mediated by 3'5'-cyclic Adenosine 5'-monophosphate-dependent Protein Kinase II"
  • 56. Vasconsuelo A., Giulietti A. M.Boland R. L., Plant Sci., 166, 405 - 413 (2004), "Signal Transduction Events Mediating Chitosan Stimulation of Anthraquinone Synthesis in Rubia Tinctorum"
  • 57. Fleming Y. M., Frame M. C.Houslay M. D., J. Cell. Sci., 117, 2377 - 2388 (2004), "PDE4-regulated cAMP Degradation Controls the Assembly of Integrin-dependent Actin Adhesion Structures and REF52 Cell Migration"
  • 58. Zhong N.Zucker R. S., J. Neurosci., 24, 4205 - 4212 (2004), "Roles of Ca2+, Hyperpolarization and Cyclic Nucleotide-activated Channel Activation, and Actin in Temporal Synaptic Tagging"
  • 59. Genieser H.-G., Bos J. L., Christensen A. E., Doeskeland S. O., Havemann U., Manzau U., Rehmann H.Schwede F., Poster #THP016 Montreal, 12, 0 - 0 (2004), "Analogues of Cyclic AMP to Distinguish Between PKA and Epac"
  • 60. Dyachok O.Gylfe E., J. Biol. Chem., 279, 45455 - 45461 (2004), "Ca2+-induced Ca2+ Release via Inositol 1,4,5-triphosphate Receptors is Amplified by Protein Kinase A and Triggers Exocytosis in Pancreatic Beta-cells"
  • 61. Gambaryan S., Geiger J., Schwarz U. R., Butt E., Begonja A., Obergfell A.Walter U., Blood, 103, 2593 - 2600 (2004), "Potent Inhibition of Human Platelets by cGMP Analogs Independent of cGMP-dependent Protein Kinase"
  • 62. Zhang H., Conrad D. M., Butler J. J., Zhao C. L., Blay J.Hoskin D. W., J. Immunol., 173, 932 - 944 (2004), "Adenosine Acts Through A(2)Receptors to Inhibit IL-2-Induced Tyrosine Phosphorylation of STAT5 in T Lymphocytes: Role of Cyclic Adenosine 3', 5'-monophosphate and Phosphatases"
  • 63. Shimoni Y.Liu X. F., Am. J. Physiol.-Heart Circul. Physiol., 287, 311 - 319 (2004), "Gender Differences in ANG II Levels and Action on Multiple K+ Current Modulation Pathways in Diabetic Rats"
  • 64. Podda M. V., Marcocci M. E., Oggiano L., D'Ascenzo M., Tolu E., Palamara A. T., Azzena G. B.Grassi C., Eur. J. Neurosci., 20, 2124 - 2132 (2004), "Nitric Oxide Increases the Spontaneous Firing Rate of Rat Medial Vestibular Nucleus Neurons in Vitro via a Cyclic GMP-mediated PKG-independent Mechanism"
  • 65. Schröder F., Klein G., Frank T., Bastein M., Indris S., Karck M., Drexler H.Wollert K. C., J. Mol. Cell. Cardiol., 37, 735 - 745 (2004), "Src Family Tyrosine Kinases Inhibit Single L-type: Ca2+ Channel Activity in Human Atrial Myocytes"
  • 66. Fricke K., Heitland A.Maronde E., Endocrinology, 145, 4940 - 4947 (2004), "Cooperative Activation of Lipolysis by Protein Kinase A and Protein Kinase C Pathways in 3T3-L1 Adipocytes"
  • 67. Waleh N., Kajino H., Marrache A. M., Ginzinger D., Roman C., Seidner S. R., Moss T. J. M., Fouron J. C., Vazquez-Tello A., Chemtob S.Clyman R. I., Circulation, 110, 2326 - 2332 (2004), "Prostaglandin E-2 Mediated Relaxation of the Ductus Arteriosus - Effects of Gestational Age on G Protein-coupled Receptor Expression, Signaling, and Vasomotor Control"
  • 68. Chen L., Wang P., Andrade C. F., Zhao I. Y., Dube P. E., Brubaker P. L., Liu M.Jin T., FEBS J., 272, 2746 - 2759 (2004), "PKA Independent and Cell Type Specific Activation of the Expression of Caudal Homeobox Gene Cdx-2 by cyclic AMP"
  • 69. Runyon S. L., Washicosky K. J., Brenneman R. J., Kelly J. R., Khadilkar R. V., Heacock K. F., McCormick S. M., Williams K. E.Jinks R. N., Visual Neurosci., 21, 749 - 763 (2004), "Central Regulation of Photosensitive Membrane Turnover in the Lateral Eye of Limulus. II. Octopamine Acts via Adelynate Cyclase/cAMP-dependent Protein Kinase to Prime the Retina for Transient Rhabdom Shedding"
  • 70. Kang G., Joseph J. W., Chepurny O. G., Monaco M., Wheeler M. B., Bos J. L., Schwede F., Genieser H.-G.Holz G. G., J. Biol. Chem., 278, 8279 - 8285 (2003), "Epac-Selective cAMP Analog 8-pCPT-2'-O-Me-cAMP As A Stimulus For Ca 2+ -Induced Ca 2+ Release And Exocytosis In Pancreatic Beta-Cells"
  • 71. Rangarajan S., Enserink J. M., Kuiperij H. B., de Rooij J., Price L. S., Schwede F.Bos J. L., J. Cell Biol., 160, 487 - 493 (2003), "Cyclic AMP Induces Integrin-mediated Cell Adhesion Through Epac and Rap1 Upon Stimulation of the ß2-Adrenergic Receptor"
  • 72. Ding W. Q., Dong M. Q., Ninova D., Holicky E. L., Stegall M. D.Miller L. J., Cell. Signal., 15, 27 - 35 (2003), "Forskolin Suppresses Insulin Gene Transcription in Islet Beta-Cells through a Protein Kinase A-independent Pathway"
  • 73. Rehmann H., Schwede F., Doeskeland S. O., Wittinghofer A.Bos J. L., J. Biol. Chem., 278, 38548 - 38556 (2003), "Ligand-mediated Activation of the cAMP-responsive Guanine Nucleotide Exchange Factor Epac"
  • 74. Hirakawa T.Ascoli M., Mol. Endocrinol., 17, 2189 - 2200 (2003), "The Lutropin/Choriogonadotropin Receptor (LHR)-induced Phosphorylation of the Extracellular Signal Regulated Kinases (ERKs) in Leydig Cells is Mediated by a Protein Kinase A-dependent Activation of Ras"
  • 75. Bartsch M., Zorn-Kruppa M., Kühl N., Genieser H.-G., Schwede F.Jastorff B., Biol. Chem., 384, 1321 - 1326 (2003), "Bioactivatable, Membrane-permeant Analogs of Cyclic Nucleotides as Biological Tools for Growth Control of C6 Glioma Cells"
  • 76. Sun X. G.Dalman F. C., Brain Res., 973, 122 - 130 (2003), "Evidence for Multiple Mechanisms of Kappa Opioid Tolerance in Mesencephalic Cultures"
  • 77. Christensen A. E., Selheim F., de Rooij J., Dremier S., Schwede F., Dao K. K., Martinez A., Maenhaut C., Bos J. L., Genieser H.-G.Doeskeland S. O., J. Biol. Chem., 278, 35394 - 35402 (2003), "cAMP Analog Mapping of Epac1 and cAMP-Kinase. Discriminating Analogs Demonstrate that Epac and cAMP-Kinase Act Synergistically to Promote PC-12 Cell Neurite Extension"
  • 78. Hagen V., Frings S., Wiesner B., Helm S., Kaupp U. B.Bendig J., Chembiochem., 4, 434 - 442 (2003), "[7-(Dialkylamino)Coumarin-4-yl]Methyl-Caged Compounds as Ultrafast and Effective Long-wavelength Phototriggers of 8-Bromo-Substituted Cyclic Nucleotides"
  • 79. Maillet M., Robert S. J., Cacquevel M., Gastineau M., Vivien D., Bertoglio J., Zugaza J. L., Fischmeister R.Lezoualc'h F., Nat. Cell Biol., 5, 633 - 639 (2003), "Crosstalk between Rap1 and Rac Regulates Secretion of sAPP Alpha"
  • 80. Li D., Wen J. F., Jin J. Y., Ann H. S., Kim S. Z., Lee H. S.Cho K. W., Am. J. Physiol.-Regul. Integr. Comp. Physiol., 285, 380 - 393 (2003), "Histamine Inhibits Atrial Myocytic ANP Release via H-2 Receptor-cAMP-Protein Kinase Signalling"
  • 81. Christensen A. E.Doeskeland S. O., Handbook of Cell Signaling Academic Press/Elsevier Science San Diego CA, 2, 549 - 554 (2003), "Cyclic Nucleotide Analogs as Tools to Investigate Cyclic Nucleotide Signaling"
  • 82. West G. A., Meno J. R., Nguyen T.-S. K., Ngai A. C., Simard J. M.Winn H. R., J. Cardiovasc. Pharmacol., 41, 444 - 451 (2003), "cGMP-dependent and not cAMP-dependent Kinase is Required for Adenosine-induced Dilation of Intracerebral Arterioles"
  • 83. Lu Z., Kolodecik T. R., Karne S., Nyce M.Gorelick F., Am. J. Physiol. Gastrointest. Liver Physiol., 285, 822 - 828 (2003), "Effect of Ligands that Increase cAMP on Caerulein-induced Zymogen Activation in Pancreatic Acini"
  • 84. Yin W., Mu J.Birnbaum M. J., J. Biol. Chem., 278, 43074 - 43080 (2003), "Role of AMP-activated Protein Kinase in Cyclic AMP-dependent Lipolysis in 3T3-L1 Adipocytes"
  • 85. Wyatt T. A., Forget M. A.Sisson J. H., Am. J. Pathol., 163, 1157 - 1166 (2003), "Ethanol stimulates Ciliary Beating by Dual Cyclic Nucleotide Kinase Activation in Bovine Bronchial Epithelial Cells"
  • 86. Giordano D., Magaletti D. M., Clark E. A.Beavo J. A., J. Immunol., 171, 6421 - 6430 (2003), "Cyclic Nucleotides Promote Monocyte Differentiation Toward a DC-SGN+ (CD209) Intermediate Cell and Impair Differentiation into Dendritic Cells"
  • 87. Yan L., Zhang Q. H., Scholz P. M.Weiss H. R., Clin. Exp. Pharmacol. Physiol., 30, 943 - 950 (2003), "Cyclic GMP Protein Kinase Activity Is Reduced in Thyroxine-induced Hypertrophic Cardiac Myocytes"
  • 88. Ciranna L.Cavallaro S., Exp. Neurol., 184, 778 - 784 (2003), "Opposing Effects by Pituiary Adenylate Cyclase-activating Polypeptide and Vasoactive Intestinal Peptide on Hippocampal Synaptic Transmission"
  • 89. Frajnt M., Cytrynska M.Jakubowicz T., Acta Biochim. Polon., 50, 1111 - 1118 (2003), "The Effect of cAMP and cGMP on the Activity and Substrate Specificity of Protein Kinase A from Methylotrohic Yeast Pichia Pastoris"
  • 90. Christensen A. E., de Rooij J., Kopperud R. K., Nilsen O. K., Dao K. K., Schwede F., Bos J. L., Genieser H.-G.Doeskeland S. O., Abstract of the 13th Protein Kinase Symposium, 0, 5 - 5 (2002), "Comparison of the cAMP Binding Sites of EPAC-1 and cAMP-Kinase"
  • 91. Doi A., Ishibashi H., Jinno S., Kosaka T.Akaike N., Neuroscience, 109, 299 - 311 (2002), "Presynaptic Inhibition of GABAergic Miniature Currents by Metabotropic Glutamate Receptor in the Rat CNS"
  • 92. Johnston C. A., Beazely M. A., Vancura A. F., Wang J. K. T.Watts V. J., J. Neurochem., 82, 1087 - 1096 (2002), "Heterologous Sensitization of Adenylate Cyclase is Protein Kinase A-dependent in Cath.a Differentiated (CAD)-D-2L Cells"
  • 93. Oz M., Zhang L.Spivak C. E., Arch. Biochem. Biophys., 404, 293 - 301 (2002), "Direct Noncompetitive Inhibition of 5-HT3 Receptor-mediated Responses by Forskolin and Steroids"
  • 94. Ibarra-Alvarado C., Galle J., Melichar V. O., Mameghani A.Schmidt H. H. H. W., Mol. Pharmacol., 61, 312 - 319 (2002), "Phosphorylation of Blood Vessel Vasodilator-stimulated Phosphoprotein at Serine 239 as a Functional Biochemical Marker of Endothelial Nitric Oxide/Cyclic GMP Signaling"
  • 95. Gao Y. S.Raj J. U., Eur. J. Pharmacol., 436, 227 - 233 (2002), "Effects of SQ 22536, an Adenylyl Cyclase Inhibitor, on Isoproterenol-induced Cylic AMP Elevation and Relaxation in Newborn Ovine Pulmonary Veins"
  • 96. Held B., Freise D., Freichel M., Hoth M.Flockerzi V., J. Physiol.-London, 539, 459 - 468 (2002), "Skeletal Muscle L-Type Ca2+ Current Modulation in Gamma 1-deficient and Wildtype Murine Myotubes by the Gamma 1 Subunit and cAMP"
  • 97. Roozendaal B., Quirarte G. L.McGaugh J. L., Eur. J. Neurosci., 15, 553 - 560 (2002), "Glucocorticoids Interact with the Basolateral Amygdala Beta-Adrenoceptor-cAMP/PKA System in Influencing Memory Consolidation"
  • 98. Wenzel B., Elsner N.Heinrich R., J. Neurophysiol., 87, 876 - 888 (2002), "mAChRs in the Grasshopper Brain Mediate Excitation by Activation of the AC/PKA and the PLC Second-Messenger Pathways"
  • 99. Maderna P., Cottell D. C., Berlasconi G., Petasis N. A., Brady H. R.Godson C., Am. J. Pathol., 160, 2275 - 2283 (2002), "Lipoxins Induce Actin Reorganization in Monocytes and Macrophages but not in Neutrophils - Differential Involvement of Rho GTPases"
  • 100. Goaillard J. M.Vincent P., J. Physiol.-London, 541, 453 - 465 (2002), "Serotonin Suppresses the Slow Afterhyperpolarization in Rat Intralaminar and Midline Thalamic Neurones by Activating 5-HT7 Receptors"
  • 101. Lamb D.Steinberg R. A., J. Cell. Physiol., 192, 216 - 224 (2002), "Anti-Proliferative Effects of 8-Chloro-cAMP and other cAMP Analogs Are Unrelated to Their Effects on Protein Kinase A Regulatory Subunit Expression"
  • 102. Enserink J. M., Christensen A. E., de Rooij J., van Triest M., Schwede F., Genieser H.-G., Doeskeland S. O., Blank J. L.Bos J. L., Nature Cell Biol., 4, 901 - 906 (2002), "A Novel Epac-specific cAMP Analogue Demonstrates Independent Regulation of Rap 1 and ERK"
  • 103. Nishimura K., Tamaoki J., Isono K., Aoshiba K.Nagai A., Eur. Resp. J., 20, 353 - 358 (2002), "Beta-Adrenergic Receptor-Mediated Growth of Human Airway Epithelial Cell Lines"
  • 104. Laroche-Joubert N., Marsy S., Michelet S., Imbert-Teboul M.Doucet A., J. Biol. Chem., 277, 18598 - 18604 (2002), "Protein Kinase A-independent Activation of ERK and H,K-ATPase by cAMP in Native Kidney Cells"
  • 105. Oz M., Zhang L.Morales M., Synapse, 46, 150 - 156 (2002), "Endogenous Cannabinoid, Anandamide, Acts as a Noncompetitive Inhibitor on 5-HT3 Receptor-mediated Responses in Xenopus Oocytes"
  • 106. Abe K., Hosoi R., Momosaki S., Kobayashi K., Ibii N.Inoue O., Brain Res., 952, 211 - 217 (2002), "Increment of in Vivo Binding of [H-3]SCH 23390, a Dopamine D-1 Receptor Ligand, Induced by Cyclic AMP-dependent Protein Kinase in Rat Brain"
  • 107. Saavedra A. P., Tsygankova O. M., Prendergast G. V., Dworet J. H., Cheng G.Meinkoth J. L., Oncogene, 21, 778 - 788 (2002), "Role of cAMP, PKA and Rap 1A in Thyroid Follicular Cell Survival"
  • 108. Roesler R., Roozendaal B.McGaugh J. L., Eur. J. Neurosci., 15, 905 - 910 (2002), "Basolateral Amygdala Lesions Block the Memory-enhancing Effect of 8-Br-cAMP Infused into the Entorhinal Cortex of Rats after Training"
  • 109. Zoraghi R.Seebeck T., PNAS, 99, 4243 - 4348 (2002), "The CAMP-specific Phosphodiesterase is an Essential Enzyme In Bloodstream Form Trypanosoma Brucei"
  • 110. Hahnefeld C.Herberg F. W., Abstract of the 13th Protein Kinase Symposium p. 14, 0, 12 - 15 (2002), "cAMP-dependent Protein Kinase: cAMP Analog Screening Using Surface Plasmon Resonance and Fluorescent Methods"
  • 111. Rodriguez-Collazo P., Snyder S. K., Chiffer R. C., Zlatanova J., Leuba S. H.Smith C. L., Exp. Cell Res., 3, 1 - 10 (2002), "cAMP signaling induces rapid loss of histone H3 phosphorylation in mammary adenocarcinoma-derived cell lines"
  • 112. Katsurabayashi S., Kubota H., Wang Z. M., Rhee J. S.Akaike N., J. Neurophysiol., 85, 332 - 340 (2001), "cAMP-Dependent Presynaptic Regulation of Spontaneous Glycinergic IPSCs in Mechanically Dissociated Rat Spinal Cord Neurons"
  • 113. Pang L. H.Knox A. J., FASEB J., 15, 261 - 269 (2001), "Regulation of TNF-Alpha-Induced Eotaxin Release from Cultured Human Airway Smooth Muscle Cells by Beta(2)-Agonists and Corticosteroids"
  • 114. Zhi-Wen Y., Buren J., Enerbäck S., Nilsson E., Samuelsson L.Eriksson J. W., BBA - Mol. Basis Dis., 1535, 174 - 185 (2001), "Insulin can Enhance GLUT4 Gene Expression in 3T3-F442A Cells and this Effect is Mimicked by Vanadate but Counteracted by cAMP and High Glucose - Potential Implications for Insulin Resistance"
  • 115. Ferreira J. M.Paes-de-Carvalho R., Brain Res., 900, 169 - 176 (2001), "Long-Term Activation of Adenosine A(2a) Receptors Blocks Glutamate Excitotoxicity in Cultures of Avian Retinal Neurons"
  • 116. Hatton G. I.Yang Q. Z., J. Neurosci., 21, 2974 - 2982 (2001), "Ionotropic Histamine Receptors and H2 Receptors Modulate Supraoptic Oxytocin Neuronal Excitability and Dye Coupling"
  • 117. Vara E., Arias-Diaz J., Garcia C., Balibrea J. L.Blazquez E., Am. J. Respir. Crit. Care Med., 163, 840 - 846 (2001), "Glucagon-like Peptide-1(7-34) Amide Stimulates Surfactant Secretion in Human Type II Pneumocytes"
  • 118. Heinrich R., Wenzel B.Elsner N., Proc. Natl. Acad. Sci. U. S. A., 98, 9919 - 9923 (2001), "A Role for Muscarinic Excitation: Control of Specific Singing Behavior by Activation of the Adenylate Cyclase Pathway in the Brain of Grasshoppers"
  • 119. Staples K. J., Bergmann M., Tomita K., Houslay M. D., McPhee I., Barnes P. J., Giembycz M. A.Newton R., J. Immunol., 167, 2074 - 2080 (2001), "Adenosine 3', 5'-cyclic Monophosphate (cAMP)-dependent Inhibition of IL-5 from Human T Lymphocytes is not Mediated by the cAMP-dependent Protein Kinase A(1)"
  • 120. Yan L., Patel K. N., Zhang Q. H., Scholz P. M.Weiss H. R., Eur. J. Pharmacol., 426, 11 - 19 (2001), "Interaction between Cyclic GMP Protein Kinase and Cyclic AMP May be Diminished in Stunned Cardiac Myocytes"
  • 121. Wallace D. P., Rome L. A., Sullivan L. P.Grantham J. J., Am. J. Physiol.-Renal Physiol., 280, 1019 - 1029 (2001), "cAMP-dependent Fluid Secretion in Rat Inner Medullary Collecting Ducts"
  • 122. Li B., Chik C. L., Ho A. K.Karpinski E., Endocrinology, 142, 2865 - 2873 (2001), "L-Type Ca2+ Channel Regulation by Pituitary Adenylate Cyclase-activating Polypeptide in Vascular Myocytes from Spontaneously Hypertensive Rats"
  • 123. Huang S. N.Swaan P. W., J. Pharmacol. Exp. Ther., 298, 264 - 271 (2001), "Riboflavin Uptake in Human Trophoblast-derived BeWo Cell Monolayers: Cellular Translocation and Regulatory Mechanisms"
  • 124. Zhang X. P.Hintze T. H., Arterioscler. Thromb. Vasc. Biol., 21, 797 - 803 (2001), "cAMP Signal Transduction Cascade, a Novel Pathway for the Regulation of Endothelial Nitric Oxide Production in Coronary Blood Vessels"
  • 125. Banerjee C.Sarkar D., Comp. Biochem. Physiol. PT C, 130, 217 - 226 (2001), "The cAMP-binding Proteins of Leishmania are not the Regulatory Subunits of cAMP-dependent Protein Kinase"
  • 126. Fleischhauer J. C., Mitchell C. H., Peterson-Yantorno K., Coca-Prados M.Civan M. M., Am. J. Physiol.-Cell Physiol., 281, 1614 - 1623 (2001), "PGE2, Ca2+, and cAMP Mediate ATP Activation of Cl- Channels in Pigmented Ciliary Epithelial Cells"
  • 127. Syin C., Parzy D., Traincard F., Boccaccio I., Joshi M. B., Lin D. T., Yang X.-M., Assemat K., Doerig C.Langsley G., Eur. J. Biochem., 268, 4842 - 4849 (2001), "The H89 cAMP-dependent Protein Kinase Inhibitor Blocks Plasmodium Falciparum Development in Infected Erythrocytes"
  • 128. Truss M. C., Stief C. G., Jonas U., Ückert S., Becker A. J.Forssmann W.-G., Deutsche Offenlegungsschrift, 0, 0 - 0 (2001), "Verwendung von Substanzen, die den intrazellulären Gehalt von zyklischem Adenosinmonophosphat (cAMP) erhöhen oder die Aktivität cAMP-bindender Proteine stimulieren, zur Behandlung von Erkrankungen der Harnblase"
  • 129. Wang X. L., Zhou J., Doyle M. E.Egan J. M., Endocrinology, 142, 1820 - 1827 (2001), "Glucagon-Like Peptide-1 Causes Pancreatic Duodenal Homeobox-1 Protein Translocation from the Cytoplasm to the Nucleus of Pancreatic Beta-Cells by a Cyclic Adenosine Monophosphate/Protein Kinase A-Dependent Mechanism"
  • 130. Li P.Yang X.-L., Eur. J. Physiol., 441, 739 - 745 (2001), "Forskolin Modulation of Desenzitization at GABA A and Glycine Receptors is not Mediated by cAMP-dependent Protein Kinase in Isolated Carp Amacrine-like Cells"
  • 131. Laukens K., Roef L., Witters E., Slegers H.van Onckelen H., FEBS Lett., 508, 75 - 79 (2001), "Cyclic AMP Affinity Purification and ESI-OTOF MS-MS Identification of Cytosolic Glyceraldehyde 3-phosphate Dehydrogenase and Two Nucleoside Diphosphate Kinase Isoforms from Tobacco BY-2 Cells"
  • 132. Ganapathy V., Gurlo T., Jarstadmarken H. O.von Grafenstein H., Int. Immunol., 12, 851 - 860 (2000), "Regulation of TCR-Induced IFN-Gamma Release from Islet-Reactive Non-Obese Diabetic CD8(+) T Cells by Prostaglandin E-2 Receptor Signaling"
  • 133. Schwede F., Christensen A., Liauw S., Hippe T., Kopperud R. K., Jastorff B.Doeskeland S. O., Biochemistry, 39, 8803 - 8812 (2000), "8-Substituted cAMP Analogues Reveal Marked Differences in Adaptability, Hydrogen Bonding, and Charge Accomodation between Homologous Binding Sites (AI/AII and BI/BII) in cAMP Kinase I and II"
  • 134. Xu W.Marshall A. T., J. Insect Physiol., 46, 21 - 31 (2000), "Control of Ion and Fluid Transport by Putative Second Messengers in Different Segments of the Malpighian Tubules of the Black Field Cricket Teleogryllus oceanicus"
  • 135. Wartenberg M., Fischer K., Hescheler J.Sauer H., Int. J. Cancer, 85, 267 - 274 (2000), "Redox Regulation of P-Glycoprotein-Mediated Multidrug Resistance in Multicellular Prostate Tumor Spheroids"
  • 136. Kishi M., Takeuchi T., Katayama H., Yamazaki Y., Nishio H., Hata F.Takewaki T., Br. J. Pharmacol., 129, 140 - 146 (2000), "Involvement of Cyclic AMP-PKA Pathway in VIP-Induced, Charybdotoxin-Sensitive Relaxation of Longitudinal Muscle of the Distal Colon of Wistar-ST Rats"
  • 137. Gertzberg N., Clements R., Jaspers I., Ferro T. J., Neumann P., Flescher E.Johnson A., Am. J. Respir. Cell. Mol. Biol., 22, 105 - 115 (2000), "Tumor Necrosis Factor-Alpha Induced Activating Protein-1 Activity is modulated by Nitric Oxide-Mediated Protein Kinase G Activation"
  • 138. Ben-Haim G.Armstead W. M., Brain Res., 853, 330 - 337 (2000), "Stimulus Duration-Dependent Contribution of K-Ca Channel Activation and cAMP to Hypoxic Cerebrovasodilation"
  • 139. Harrison D. A., Carr D. W.Meizel S., Biol. Reprod., 62, 811 - 820 (2000), "Involvement of Protein Kinase A and a Kinase Anchoring Protein in the Progesterone-Initiated Human Sperm Acrosome Reaction"
  • 140. Viard P., Macrez N., Coussin F., Morel J.-L.Mironneau J., Br. J. Pharmacol., 129, 1497 - 1505 (2000), "Beta-3 Adrenergic Stimulation of L-Type Ca2+ Channels in Rat Portal Vein Myocytes"
  • 141. Yamaguchi T., Pelling J. C., Ramaswamy N. T., Eppler J. W., Wallace D. P., Nagao S., Rome L. A., Sullivan L. P.Grantham J. J., Kidney Int., 57, 1460 - 1471 (2000), "cAMP Stimulates the in Vitro Proliferation of Renal Cyst Epithelial Cells by Activating the Extracellular Signal-Regulated Kinase Pathway"
  • 142. Teoh H.Man R. Y. K., Br. J. Pharmacol., 129, 1739 - 1747 (2000), "Enhanced Relaxation of Porcine Coronary Arteries after Acute Exposure to a Physiological Level of 17 Beta-Estradiol Involves Non-Genomic Mechanisms and the Cyclic AMP Cascade"
  • 143. He P., Zeng M.Curry F. E., Am. J. Physiol.-Heart Circul. Physiol., 278, 1124 - 1133 (2000), "Dominant Role of cAMP in Regulation of Microvessel Permeability"
  • 144. Vicentini G. E., Constantin J., Lopez C. H.Bracht A., Biochem. Pharmacol., 59, 1187 - 1201 (2000), "Transport of Cyclic AMP and Synthetic Analogs in the Perfused Rat Liver"
  • 145. Dhanakoti S. N., Gao Y. S., Nguyen M. Q.Raj J. U., J. Appl. Physiol., 88, 1637 - 1642 (2000), "Involvement of cGMP-Dependent Protein Kinase in the Relaxation of Ovine Pulmonary Arteries to cGMP and cAMP"
  • 146. Fukai T., Siegfried M. R., Ushio-Fukai M., Cheng Y., Kojda G.Harrison D. G., J. Clin. Invest., 105, 1631 - 1639 (2000), "Regulation of the Vascular Extracellular Superoxide Dismutase by Nitric Oxide and Exercise Training"
  • 147. Hall A. A.Gurr S. J., Physiol. Mol. Plant Pathol., 56, 39 - 46 (2000), "Initiation of Appressorial Germ Tube Differentiation and Appressorial Hooking: Distinct Morphological Events Regulated by cAMP Signalling in Blumeria graminis f. sp. hordei"
  • 148. Wang A., Martin J. A., Lembke L. A.Midura R. J., J. Biol. Chem., 275, 11082 - 11091 (2000), "Reversible Suppression of In Vitro Biomineralization by Activation of Protein Kinase A"
  • 149. Chappell P. E., Lee J.Levine J. E., Endocrinology, 141, 1486 - 1492 (2000), "Stimulation of Gonadotropin-Releasing Hormone Surges by Estrogen. II. Role of Cyclic Adenosine 3',5'-Monophosphate"
  • 150. Uphouse L., Maswood S.Jackson A., Pharmacol. Biochem. Behav., 66, 383 - 388 (2000), "Factors Elevating cAMP Attenuate the Effects of 8-OH-DPAT on Lordosis Behavior"
  • 151. Pemberton K. E., Hill-Eubanks L. J.Jones S. V. P., Pflugers Arch., 440, 452 - 461 (2000), "Modulation of Low-Threshold T- Type Calcium Channels by the Five Muscarinic Receptor Subtypes in NIH 3T3 Cells"
  • 152. Christensen A., Dao K. K., Doeskeland S. O., Schwede F., Jastorff B., Genieser H.-G., de Rooij J., Bos J. L., Rehmann H., Kraemer A.Wittinghofer A., 12th Protein Kinase Symp. NO/cGMP and Protein Kinase Signaling Bad Brückenau/Germany, 0, 0 - 0 (2000), "8-Modified cAMP Analogs give Insight into the Geometries of the cAMP Binding Sites of RI, RII and EPAC-1"
  • 153. Hagen V., Bendig J., Frings B., Wiesner B.Kaupp U. B., 12th Protein Kinase Symp. NO/cGMP and Protein Kinase Signaling Bad Brückenau/Germany, 0, 0 - 0 (2000), "Novel Coumarinylmethyl-Caged Cyclic Nucleotides: Photochemistry and Application to Cyclic Nucleotide-Gated Channels"
  • 154. Indolfi C., Di Lorenzo E., Rapacciuolo A., Stingone A. M., Stabile E., Leccia A., Torella D., Caputo R., Ciardiello F., Tortora G.Chiariello M., J. Amer. Coll. Cardiol., 36, 288 - 293 (2000), "8-Chloro-cAMP Inhibits Smooth Muscle Cell Proliferation In Vitro and Neointima Formation Induced by Balloon Injury In Vivo"
  • 155. Pham N., Cheglakov I., Koch C. A., de Hoog C. L., Moran M. F.Rotin D., Curr. Biol., 10, 555 - 558 (2000), "The Guanine Nucleotide Exchange Factor CNrasGEF Activates Ras in Response to cAMP and cGMP"
  • 156. Schwede F., Maronde E., Genieser H.-G.Jastorff B., Pharmacol. Ther., 87, 199 - 226 (2000), "Cyclic Nucleotide Analogs as Biochemical Tools and Prospective Drugs"
  • 157. Koizumi M.Breaker R. R., Biochemistry, 39, 8983 - 8992 (2000), "Molecular Recognition of cAMP by an RNA Aptamer"
  • 158. Chiang C. H., Cheng K. W., Igarashi S., Nathwani P. S.Leung P. C. K., J. Clin. Endocrinol. Metab., 85, 3828 - 3839 (2000), "Hormonal Regulation of Estrogen Receptor Alpha and Beta Gene Expression in Human Granulosa-Luteal Cells In Vitro"
  • 159. Koh D. S., Moody M. W., Nguyen T. D.Hille B., J. Gen. Physiol., 116, 507 - 519 (2000), "Regulation of Exocytosis by Protein Kinases and Ca2+ in Pancreatic Duct Epithelial Cells"
  • 160. Chan J. S. D., Wang T. T., Zhang S. L., Chen X.Carriere S., Mol. Cell. Biochem., 212, 73 - 79 (2000), "Catecholamines and Angiotensinogen Gene Expression in Kidney Proximal Tubular Cells"
  • 161. Klein G., Drexler H.Schröder F., Cardiovasc. Res., 48, 367 - 374 (2000), "Protein Kinase G Reverses all Isoproterenol Induced Changes of Cardiac Single L-Type Calcium Channel Gating"
  • 162. Hardy T. A.Brock J. A., Naunyn-Schmied. Arch. Pharmacol., 362, 559 - 567 (2000), "Effects of Agents that Modulate Intracellular cAMP Levels on Excitatory Junction Potentials Recorded in the Guinea-Pig Vas Deferens In Vitro"
  • 163. Lee R. K. K.Wurtman R. J., US Patent 6224 of March 28, 43, 0 - 0 (2000), "Compositions and Methods for Treatment of Neurological Disorders and Neurodegenerative Diseases"
  • 164. Lamb J., Ladha M. H., McMahon C., Sutherland R. L.Ewen M. E., Mol. Cell. Biol., 20, 8667 - 8675 (2000), "Regulation of the Functional Interaction between Cyclin D1 and the Estrogen Receptor"
  • 165. Kroeber S., Meissl H., Maronde E.Korf H.-W., J. Neurochem., 74, 2478 - 2489 (2000), "Analyses of Signal Transduction Cascades Reveal an Essential Role of Calcium Ions for the regulation of Melatonin Biosynthesis in the Light -Sensitive Pineal Organ of the Rainbow Trout (Oncorhynchus Mykiss)"
  • 166. Arai H., Xin K.-Q., Hamajima K., Lu Y., Watabe S., Takahashi T., Toda S., Kudoh I., Suzuki M.Okuda K., Gene Therapy, 7, 694 - 702 (2000), "8-Br-cAMP Enhances Both Humoral and Cell-mediated Immune Responses Induced by an HIV-1 DNA Vaccine"
  • 167. Rodriguez P., Snyder S. K., Chiffer R. C.Smith C. L., Manuskript, 0, 0 - 0 (2000), "cAMP Signaling Induces Rapid Dephosphorylation of Histone H3 Independently of Protein Kinase A and Epac"
  • 168. Wang C. Y., Aronson I., Takuma S., Homma S., Naka Y., Alshafie T., Brovkovych V., Malinski T., Oz M. C.Pinsky D. J., Circ. Res., 86, 982 - 988 (2000), "cAMP Pulse During Preservation Inhibits the Late Development of Cardiac Isograft and Allograft Vasculopathy"
  • 169. Bagley E. E., Vaughan C. W.Christie M. J., J. Physiol., 516, 219 - 225 (1999), "Inhibition by Adenosine Receptor Agonists of Synaptic Transmission in Rat Periaqueductal Grey Neurons"
  • 170. De Fouw L. M.De Fouw D. O., Microvasc. Res., 57, 19 - 29 (1999), "Modulation of Angiogenic Endothelial Permselectivity by the cAMP Pathway"
  • 171. MacKenzie W. M., Hoskin D. W.Blay J., Biochem. Biophys. Res. Commun., 255, 460 - 465 (1999), "The Adhesion of Anti-CD3-Activated Mouse T Cells to Syngeneic Colon Adenocarcinoma Cells is Differentially Regulated by Protein Tyrosine Kinase-, Protein Kinase C-, and cAMP-Dependent Pathways in the Effector Cell"
  • 172. Wang T. T., Chen X., Wu X. H., Zhang S. L.Chan J. S. D., Kidney Int., 55, 1713 - 1723 (1999), "Molecular Mechanism(s) of Action of Isoproterenol on the Expression of the Angiotensinogen Gene in Opossum Kidney Proximal Tubular Cells"
  • 173. Holz G. G., Leech C. A., Heller R. S., Castonguay M.Habener J. F., J. Biol. Chem., 274, 14147 - 14156 (1999), "cAMP-Dependent Mobilization of Intracellular Ca2+ Stores by Activation of Ryanodine Receptors in Pancreatic Beta-Cells - A Ca2+ Signalling System Stimulated by the Insulinotropic Hormone Glucagone-Like Peptide-1-(7-37)"
  • 174. Janvier J. J., Garcia-Estan J.Hernandez J., Life Sci., 64, 2383 - 2389 (1999), "Diazepam Reduces Action Potential Duration in Guinea-Pig Papillary Muscle by a cAMP-Dependent Mechanism"
  • 175. An R. H., Heath B. M., Higgins J. P., Koch W. J., Lefkowitz R. J.Kass R. S., J. Physiol.-London, 516, 19 - 30 (1999), "Beta(2)-Adrenergic Receptor Overexpression in the Developing Mouse Heart: Evidence for Targeted Modulation of Ion Channels"
  • 176. Zhou X.-L., Lei Z. M.Rao C. V., J. Clin. Endocrinol. Metab., 84, 3364 - 3377 (1999), "Treatment of Human Endometrial Gland Epithelial Cells with Chorionic Gonadotropin/Luteinizing Hormone Increases the Expression of the Cyclooxygenase-2 Gene"
  • 177. Wu M. L., Chen W. H., Liu I. H., Tseng C. D.Wang S. M., J. Neurochem., 73, 1318 - 1328 (1999), "A Novel Effect of Cyclic AMP on Capacitative Ca2+ Entry in Cultured Rat Cerebellar Astrocytes"
  • 178. Hoenderop J. G. J., Vaandrager A. B., Dijkink L., Smolenski A., Gambaryan S., Lohmann S. M., De Jonge H. R., Willems P. H. G. M.Bindels R. J. M., Proc. Natl. Acad. Sci., 96, 6084 - 6089 (1999), "Atrial Natriuretic Peptide-Stimulated Ca2+ Reabsorption in Rabbit Kidney Requires Membrane-Targeted, cGMP-Dependent Protein Kinase Type II"
  • 179. Fan Y.-P., Chakder S.Rattan S., Am. J. Physiol.-Gastroint. Liver Physiol., 40, 152 - 160 (1999), "Mechanisms of Action of Cholera Toxin on the Opossum Internal Anal Sphincter Smooth Muscle"
  • 180. Hein T. W.Kuo L., Circ. Res., 85, 634 - 642 (1999), "cAMP-Independent Dilation of Coronary Arterioles to Adenosine - Role of Nitric Oxide, G Proteins, and K-ATP Channels"
  • 181. Zhang L., Karpinski E.Benishin C. G., Neurochem. Int., 35, 345 - 355 (1999), "Prostaglandin E-2 Modulates a Non-Inactivating Potassium Current in Rat Neurohypophyseal Nerve Terminals"
  • 182. Haug L. S., Jensen V., Hvalby E., Walaas S. I.Estvold A. C., J. Biol. Chem., 274, 7467 - 7473 (1999), "Phosphorylation of the Inositol 1,4,5-Triphosphate Receptor by Cyclic Nucleotide-Dependent Kinases in Vitro and in Rat Cerebellar Slices in Situ"
  • 183. Bouron A., Eur. J. Neurosci., 11, 4446 - 4450 (1999), "Adenosine Suppresses Protein Kinase A- and C-Induced Enhancement of Glutamate Release in the Hippocampus"
  • 184. Collins S. P.Uhler M. D., J. Biol. Chem., 274, 8391 - 8404 (1999), "Cyclic AMP- and Cyclic GMP-Dependent Protein Kinases Differ in Their Regulation of Cyclic AMP Response Element-Dependent Gene Transcription"
  • 185. Hagen V., Bendig J., Frings S., Wiesner B., Schade B., Helm S., Lorenz D.Kaupp U. B., J. Photochem. Photobiol. B-Biol., 53, 91 - 102 (1999), "Synthesis, Photochemistry and Application of (7-Methoxycoumarin-4-yl)Methyl-Caged 8-Bromoadenosine Cyclic 3', 5'-Monophosphate and 8-Bromoguanosine Cyclic 3', 5'-Monophosphate Photolyzed in the Nanosecond Time Region"
  • 186. Kopp M. D. A., Schomerus C., Dehghani F., Korf H. W.Meissl H., J. Neurosci., 19, 206 - 219 (1999), "Pitutary Adenylate Cyclase-activating Pölypeptide and Melatonin in the Suprachiasmatic Nucleus: Effects on the Calcium Signal Transduction Cascade"
  • 187. Pohnke Y., Kempf R.Gellersen B., J. Biol. Chem., 274, 24818 - 24818 (1999), "CCAAT/Enhancer-binding Proteins Are Mediators in the Protein kinase A-dependent Activation of the Decidual Prolactin Promoter"
  • 188. Zheng J., Ghorpade A., Niemann D., Cotter R. L., Thylin M. R., Epstein L., Swartz J. M., Shepard R. B., Liu X., Nukuna A.Gendelman H. E., J. Virol., 73, 8256 - 8267 (1999), "Lymphotropic Virions Affect Chemokine Receptor-Mediated Neural Signaling and Apoptosis: Implications for Human Immunodefiency Virus Type 1-Associated Dementia"
  • 189. Taylor M. S., McMahon A. M., Gardner J. D.Benoit J. N., Pathophysiology, 5, 233 - 245 (1999), "Cyclic nucleotides and vasoconstrictor function: physiological and pathophysiological considerations"
  • 190. Cho-Chung Y. S., Jastorff B.Genieser H.-G., USA patent 5916, 843, 0 - 0 (1998), "Cyclic AMP Analogues, Individually and in Pairs, to Inhibit Neoplastic Cell Growth"
  • 191. Vischer U. M.Wollheim C. B., Blood, 91, 118 - 127 (1998), "Purine Nucleotides Induce Regulated Secretion of von Willebrand Factor - Involvement of Cytosolic Ca 2+ and Cyclic Adenosine Monophosphate-dependent Signaling in Endothelial Exocytosis"
  • 192. Ingram S. L., Vaughan C. W., Bagley E. E., Connor M.Christie M. J., J. Neurosci., 18, 10269 - 10276 (1998), "Enhanced Opioid Efficacy in Opioid Dependence is Caused by an Altered Signal Transduction Pathway"
  • 193. Torrens Y., Beaujouan J.-C., Saffroy M., Glowinski J.Tencé M., J. Neurochem., 70, 2091 - 2098 (1998), "Functional Coupling of the NK1 Tachykinin Receptor to Phospholipase D in Chinese Hamster Ovary Cells and Astrocytoma Cells"
  • 194. Ruiz-Velasco V., Zhong J., Hume J. R.Keef K. D., Circ. Res., 82, 557 - 565 (1998), "Modulation of Ca2+ Channels by Cyclic Nucleotide Cross Activation of Opposing Protein Kinases in Rabbit Portal Vein"
  • 195. Keryer G., Alsat E., Tasken K.Evain-Brion D., J. Cell Sci., 111, 995 - 1004 (1998), "Cyclic AMP-dependent Protein Kinases and Human Trophoblast Cell Differentiation in Vitro"
  • 196. Garcia-Ocana A., Gomez-Casero E., Penaranda C.Esbrit P., Life Sci., 62, 2267 - 2273 (1998), "Parathyroid Hormone-related Protein Increases DNA Synthesis in Proximal Tubule Cells by Cyclic AMP- and Protein Kinase C-dependent Pathways"
  • 197. Maeda T., Murase N., Subbotin V., Sakamoto T., Yamada T., Terakura M.Todo S., Transplantation, 66, 844 - 851 (1998), "Analogs of Cyclic Nucleotides in Rat Liver Preservation"
  • 198. Sabatier N., Richard P.Dayanithi G., J. Physiol.-London., 513, 699 - 710 (1998), "Activation of Multiple Intracellular Transduction Signals by Vasopressin in Vasopressin-sensitive Neurones of the Rat Supraoptic Nucleus"
  • 199. Hagen V., Dzeja C., Bendig J., Baeger I.Kaupp U. B., J. Photochem. Photobiol., 42, 71 - 78 (1998), "Novel Caged Compounds of Hydrolysis-resistant 8-Br-cAMP and 8-Br-cGMP: Photolabile NPE Esters"
  • 200. Cho-Chung Y. S.Robins R. K., United States Patent 5752 of August 11, 792, 0 - 0 (1998), "8-Chloro cAMP and Related cAMP Compounds as Antineoplastic Agents"
  • 201. de Rooij J., Zwartkruis F. J. T., Verheijen M. H. G., Cool R. H., Nijman S. M. B., Wittinghofer A.Bos J. L., Nature, 396, 474 - 477 (1998), "Epac is a Rap 1 Guanine-Nucleotide-Exchange Factor Directly Activated by Cyclic AMP"
  • 202. Zhu W. H., Majluf-Cruz A.Omburo G. A., Life Sci., 63, 265 - 274 (1998), "Cyclic AMP-Specific Phosphodiesterase Inhibitor Rolipram and RO-20-1724 Promoted Apoptosis in HL60 Promyelocytic Leukemic Cells via Cyclic AMP-Independent Mechanism"
  • 203. Karl P. I., Divald A., Diehl A. M.Fisher S. E., Biochem. Pharmacol., 55, 45 - 51 (1998), "Altered Cyclic AMP-Dependent Human Chorionic Gonadotropin Production in Cultured Human Placental Trophoblasts Exposed to Ethanol"
  • 204. Zirpel L., Lippe W. R.Rubel E. W., J. Neurophysiol., 79, 2288 - 2302 (1998), "Activity-Dependent Regulation of [CA2+](I) in Avian Cochlear Nucleus Neurons - Roles of Protein Kinases A and C and Relation to Cell Death"
  • 205. Endoh A., Yang L.Hornsby P. J., Mol. Cell. Endocrinol., 137, 13 - 19 (1998), "CYP21 Pseudogene Transcripts are Much Less Abundant than those from the Active Gene in Normal Human Adrenocortical Cells Under Various Conditions in Culture"
  • 206. Grönroos E., Thodeti C. K.Sjölander A., Cell Calcium, 24, 9 - 16 (1998), "Leukotriene D-4 Induces a Rapid Increase in cAMP in the Human Epithelial Cell Line, INT 407 - A Potential Role for this Signal in the Regulation of Calcium Influx through the Plasma Membrane"
  • 207. Carranza M. L., Rousselot M., Chibalin A. V., Bertorello A. M., Favre H.Feraille E., J. Physiol.- London, 511, 235 - 243 (1998), "Protein Kinase A Induces Recruitment of Active NA+, K+ATPase Units to the Plasma Membrane of Rat Proximal Convoluted Tubule Cells"
  • 208. Kitamura N., Ohta T., Ito S.Nakazato Y., Pflugers Arch.-Eur. J. Physiol., 435, 781 - 788 (1998), "Calcium Channel Current Facilitation in Porcine Adrenal Chromaffin Cells"
  • 209. Jones P. M.Persaud S. J., Endocrine Rev., 19, 429 - 461 (1998), "Protein Kinases, Protein Phosphorylation, and the Regulation of Insulin Secretion from Pancreatic Beta-Cells"
  • 210. Lamprecht G., Weinman E. J.Yun C.-H. C., J. Biol. Chem., 273, 29972 - 29978 (1998), "The Role of NHERF and E3KARP in the cAMP-Mediated Inhibition of NHE3"
  • 211. Pahan K., Khan M.Singh I., J. Lipid Res., 39, 1091 - 1100 (1998), "Therapy for X-adrenoleukodystrophy: Normalization of Very Long Chain Fatty Acids and Inhibition of Induction of Cytokines by cAMP"
  • 212. Chatton J.-Y., Cao Y., Liu H.Stucki J. W., Biochem. J., 330, 1411 - 1416 (1998), "Permissive role of cAMP in the oscillatory Ca2+ response to inositol 1,4,5-trisphosphate in rat hepatocytes"
  • 213. Anciaux K., Van Dommelen K., Willems R., Roymans D.Slegers H., FEBS Lett., 400, 75 - 79 (1997), "Inhibition of Nucleoside Diphosphate Kinase (NDPK/NM23) by cAMP Analogues"
  • 214. Pahan K., Namboodiri A. M. S., Sheikh F. G., Smith B. T.Singh I., J. Biol. Chem., 272, 7786 - 7791 (1997), "Increasing cAMP Attenuates Induction of Inducible Nitric-Oxide Synthase in Rat Primary Astrocytes"
  • 215. Saati N., Ravid A., Liberman U. A.Koren R., In Vitro Cell Dev. Biol.-Plant, 33, 310 - 314 (1997), "1,25-Dihydroxyvitamin D-3 and Agents that Increase Intracellular Adenosine 3', 5'-Monophosphate Synergistically Inhibit Fibroblast Proliferation"
  • 216. Weissinger E. M., Eissner G., Grammer C., Fackler S., Haefner B., Yoon L. S., Lu K. S., Bazarow A., Sedivy J. M., Mischak H.Kolch W., Mol. Cell. Biol., 17, 3229 - 3241 (1997), "Inhibition of the Raf-1 Kinase by Cyclic AMP Agonists Causes Apoptosis of v-abl-Transformed Cells"
  • 217. Bonkale W. L., Cowburn R. F., Winblad B.Fastbom J., Brain Res., 763, 1 - 13 (1997), "Autoradiographic Characterization of (H-3)cGMP Binding Sites in the Rat Brain."
  • 218. Perez-Vallina J. R., Revuelta M. P., Cantabrana B.Hidalgo A., Life Sci., 61, 869 - 880 (1997), "Effect of RP Diastereoisomer of Adenosine 3', 5' Cyclic-Monophosphothioate on the cAMP-Dependent Relaxation of Smooth Muscle."
  • 219. Hackman J. C., Holohean A. M.Davidoff R. A., Neuroscience, 81, 1079 - 1090 (1997), "Role of Metabotropic Glutamate Receptors In the Depression of GABA-Mediated Depolarization of Frog Primary Afferent Terminals."
  • 220. Capece M. L.Lydic R., Amer. J. Physiol.- Regul. Integr. C., 42, 1430 - 1440 (1997), "cAMP and Protein Kinase A Modulate Cholinergic Rapid Eye Movement Sleep Generation"
  • 221. Hezareh M., Schlegel W.Rawlings S. R., Am. J. Physiol., 273, 850 - 858 (1997), "Stimulation of Ca2+ Influx in alphaT3-1 Gonadotrophs via the cAMP/PKA Signaling System"
  • 222. Krass J. D., Jastorff B.Genieser H.-G., Anal. Chem., 69, 2575 - 2581 (1997), "Determination of Lipophilicity by Gradient Elution High-Performance Liquid Chromatography"
  • 223. Lemos V. S., Bucher B., Cortes S. F.Takeda K., Eur. J. Neurosci., 9, 1144 - 1152 (1997), "Inhibition of [Ca2+]i Transients in Rat Adrenal Chromaffin Cells by Neuropeptide Y: Role for a cGMP-dependent Protein Kinase-activated K+ Conductance"
  • 224. Dixon D. B.Copenhagen D. R., J. Neurosci., 17, 8945 - 8954 (1997), "Metabotropic Glutamate Receptor-Mediated Suppression of an Inward Rectifier Current is Linked via a cGMP Cascade"
  • 225. Kline L. W.Pang P. K. T., Regul. Peptides, 72, 55 - 59 (1997), "Cyclic AMP Modulates Part of the Relaxant Action of Calcitonin Gene-Related Peptide in Guinea Pig Gallbladder Strips"
  • 226. Alberi S., Dreifuss J. J.Raggenbass M., Eur. J. Neurosci., 9, 2605 - 2612 (1997), "The Oxitocin-Induced Inward Current in Vagal Neurons of the Rat is Mediated by G Protein Activation but not by an Increase in the Intracellular Calcium Concentration"
  • 227. Clancy R. M., Rediske J., Tang X. Y., Nijher N., Frenkel S., Philips M.Abramson S. B., J. Clin. Invest., 100, 1789 - 1796 (1997), "Outside-In Signalling in the Chondrocyte - Nitric Oxide Disrupts Fibronectin-Induced Assembly of a Subplasmalemmal Actin RHO a Focal Adhesion Kinase Signalling Complex"
  • 228. Kruppa J., Keely S., Schwede F., Schultz C., Barrett K. E.Jastorff B., Bioorg. Med. Chem. Lett., 7, 945 - 948 (1997), "Bioactivatable Derivatives of 8-Substituted cAMP-Analogues"
  • 229. Obrietan K.van den Pol A. N., J. Neurosci., 17, 4785 - 4799 (1997), "GABA Activity Mediating Cytosolic Ca2+ Rises in Developing Neurons is Modulated by cAMP-Dependent Signal Transduction"
  • 230. Bowers R. R., Biboso A. D.Chavez O., Pigm. Cell Res., 10, 41 - 45 (1997), "The Role of Alpha-MSH, its Agonists, and cAMP in In Vitro Avian Melanocytes"
  • 231. Armstead W. M., Brain Res., 768, 177 - 84 (1997), "Role of Impaired cAMP and Calcium-Sensitive K+ Channel Function in Altered Cerebral Hemodynamics Following Brain Injury"
  • 232. Bernabeu R., Bevilaqua L., Ardenghi P. G., Bromberg E., Schmitz P., Bianchin M., Izquierdo I.Medina J. H., Proc. Natl. Acad. Sci., 94, 7041 - 7046 (1997), "Involvement of Hippocampal cAMP/cAMP-Dependent Protein Kinase Signaling Pathways in a Late Memory Consolidation Phase of Aversively Motivated Learning in Rats"
  • 233. Severin E. S., Nesterova M. V., Sashchenko L. P., Rasumova V. V., Tunitskaya V. L., Kochetkov S. N.Gulyaev N. N., BBA, 384, 413 - 422 (1997), "Investigation of the Adenosine 3', 5'- Cyclic Phosphate Binding Site of Pig Brain Histone Kinase With the Aid of Some Analogues of Adenosine 3', 5'- Cyclic Phosphate"
  • 234. Paces V.Smrz J., FEBS Lett., 31, 343 - 344 (1997), "On the Specificity of Cyclic AMP Action in Escherichia Coli"
  • 235. Sugita S., Baxter D. A.Byrne J. H., J. Neurosci., 17, 7237 - 7244 (1997), "Modulation of a cAMP/Protein Kinase A Cascade by Protein Kinase C in Sensory Neurons of Aplysia"
  • 236. Ingram S. L.Williams J. T., J. Physiol., 492, 97 - 106 (1996), "Modulation of the Hyperpolarization-activated Current (Ih) by Cyclic Nucleotides in Guinea-pig Primary Afferent Neurons"
  • 237. Wilderman M. J.Armstead W. M., Eur. J. Pharmacol., 309, 243 - 249 (1996), "Influence of cAMP on Cerebrospinal Fluid Opioid Concentration: Role in cAMP-Induced Pial Artery Dilation"
  • 238. Sandnes D., Jacobson F. W., Refsnes M.Christoffersen T., Pharmacol. Toxicol., 79, 15 - 22 (1996), "8-Bromo-cAMP and 8-CPT-cAMP Increase the Density of ß-Adrenoceptors in Hepatocytes by a Mechanism Not Mimicking the Effect of cAMP"
  • 239. Wang Y.Telfer W. H., Insect Biochem. Molec. Biol., 26, 85 - 94 (1996), "Cyclic Nucleotide-induced Termination of Vitellogenin Uptake by Hyalophora cecropia Follicles"
  • 240. Chik C. L., Li B., Ogiwara T., Ho A. K.Karpinski E., FASEB J., 10, 1310 - 1317 (1996), "PACAP Modulates L-type Ca2+ Channel Currents in Vascular Smooth Muscle Cells: Involvement of PKC and PKA"
  • 241. Nakamura A.Shiomi H., Fol. Pharmacol. Jap., 108, 143 - 148 (1996), "Signal Transduction System Involved in the Mechanism of Peripheral Mechanical Hyperalgesia"
  • 242. Pineda J., Kogan J. H.Aghajanian G. K., J. Neurosci., 16, 1389 - 1399 (1996), "Nitric Oxide and Carbon Monoxide Activate Locus Ceruleus Neurons Through a cGMP-Dependent Protein Kinase: Involvement of a Nonselective Cationic Channel"
  • 243. Stella N.Magistretti P. J., J. Biol. Chem., 271, 23705 - 23710 (1996), "Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Potentiate the Glutamate-evoked Release of Arachidonic Acid from Mouse Cortical Neurons- Evidence for a cAMP-independent Mechanism"
  • 244. Zhou X. B., Ruth P., Schlossmann J., Hofmann F.Korth M., J. Biol. Chem., 271, 19760 - 19767 (1996), "Protein Phosphatase 2A is essential for the Activation of Ca2+-activated K+ Currents by cGMP-dependent Protein Kinase in Tracheal Smooth Muscle and Chinese Hamster Ovary Cells"
  • 245. Derkinderen P., Toutant M., Burgaya F., Le Bert M., Siciliano J. C., de Franciscis V., Gelman M.Girault J.-A., Science, 273, 1719 - 1722 (1996), "Regulation of a Neuronal Form of Focal Adhesion Kinase by Anandamide"
  • 246. Miyake T., Koshimura K., Murakami Y., Tanaka J., Nishiki M.Kato Y., Biomed. Res., 17, 191 - 196 (1996), "Involvement of Tetrodotoxin-Sensitive NA+ Channel in PACAP-induced Increase in Intracellular CA2+ Concentration in GH(3) Cells"
  • 247. Heidenreich S., Otte B., Lang D.Schmidt M., J. Leucocyte Biol., 60, 737 - 743 (1996), "Infection by Candida Albicans Inhibits Apoptosis of Human Monocytes and Monocytic U937 Cells"
  • 248. Butt E.Walter U., in 'Platelets: A Practical Approach' IRL Press Oxford, 0, 259 - 278 (1996), "Cyclic Nucleotides: Measurement and Function"
  • 249. Anciaux K., Roymans D.Slegers H., Arch. Physiol. Biochem., 104, 32 - 0 (1996), "Effect of cAMP- and cGMP-Analogues on the Enzymatic Activity of the Nucleoside Diphosphate Kinase of Rat C6 Glioma"
  • 250. Han Z. Y., Chatterjee D., Early J., Pantazis P., Hendrickson E. A.Wyche J. H., Cancer Res., 56, 1621 - 1628 (1996), "Isolation and Characterization of an Apoptosis-Resistant Variant of Human Leukemia HL-60 Cells that has Switched Expression from Bcl-2 to Bcl-X(L)"
  • 251. Pfeifer A., Aszódi A., Seidler U., Ruth P., Hofmann F.Fässler R., Science, 274, 2082 - 2086 (1996), "Intestinal Secretory Defects and Dwarfism in Mice Lacking cGMP-dependent Protein Kinase II"
  • 252. Gerber U.Gahwiler B. H., J. Neurophysiol., 72, 2360 - 2367 (1995), "GABA(B) and Adenosine Receptors Mediate Enhancement of the K+ Current, I-AHP by Reducing Adenylyl Cyclase Activity in Rat CA3 Hippocampal Neurons"
  • 253. Yu S.-M., Cheng Z.-J.Kuo S.-C., Br. J. Pharmacol., 114, 1227 - 1235 (1995), "Antiproliferative Effects of A02011-1, an Adenylate Cyclase Activator, in Cultured Vascular Smooth Muscle Cells of Rat"
  • 254. Marley P. D., Thomson K. A.Bralow R. A., Br. J. Pharmacol., 114, 1687 - 1693 (1995), "Protein Kinase A and Nicotinic Activation of Bovine Adrenal Tyrosine Hydroxylase"
  • 255. Sidhu J. S.Omiecinski C. J., J. Biol. Chem., 270, 12762 - 12773 (1995), "cAMP-associated Inhibition of Phenobarbital-inducible Cytochrome P450 Gene Expression in Primary Rat Hepatocyte Cultures"
  • 256. Hernandez A., Kimball B., Romanchuk G.Mulholland M. W., Peptides, 16, 927 - 932 (1995), "Pituitary Adenylate Cyclase-Activating Peptide Stimulates Neurite Growth in PC12 Cells"
  • 257. Sculptoreanu A., Figourov A.Degroat W. C., Am. J. Physiol., 38, 725 - 732 (1995), "Voltage-dependent Potentiation of Neuronal L-type Calcium Channels Due to State-dependent Phosphorylation"
  • 258. Brignoni M., Pignataro O. P., Rodriguez M. L., Alvarez A., Vega-Salas D. E., Rodriguez-Boulan E.Salas P. J. I., J. Cell Sci., 108, 1931 - 1943 (1995), "Cyclic AMP Modulates the Rate of 'Constitutive' Exocytosis of Apical Membrane Proteins in Madin-Darby Canine Kidney Cells"
  • 259. Reale V., Hales C. N.Ashford M. L. J., J. Membr. Biol., 145, 267 - 278 (1995), "Regulation of Calcium-activated Nonselective Cation Channel Activity by Cyclic Nucleotides in the Rat Insulinoma Cell Line, CRI-G1"
  • 260. Pöhler D., Butt E., Meißner J., Müller S., Walter U., Lohmann S. M.Jarchau T., FEBS Lett., 374, 419 - 425 (1995), "Expression, Purification, and Characterization of the cGMP-dependent Protein Kinases Iß and II Using the Baculovirus System"
  • 261. Sumii K.Sperelakis N., Circ. Res., 77, 803 - 812 (1995), "cGMP-Dependent Protein Kinase Regulation of the L-Type Ca 2+ Current in Rat Ventricular Myocytes"
  • 262. Butt E., Beltman J., Becker D. E., Jensen G. S., Rybalkin S. D., Jastorff B.Baevo J. A., Mol. Pharmacol., 47, 340 - 347 (1995), "Characterization of Cyclic Nucleotide Phosphodiesterases with Cyclic AMP Analogs: Topology of the Catalytic Site and Comparison with Other Cyclic AMP-Binding Proteins"
  • 263. Eichholtz-Wirth H., Br. J. Cancer, 72, 287 - 292 (1995), "Reversal of Radiation-induced Cisplatin Resistance in Murine Fibrosarcoma Cells by Selective Modulation of the Cyclic GMP-dependent Transduction Pathway"
  • 264. Petritsch C., Woscholski R., Edelmann H. M. L.Ballou L. M., J. Biol. Chem., 270, 26619 - 26625 (1995), "Activation of p70 S6 Kinase and erk-encoded Mitogen-activated Protein Kinases is Resistant to High Cyclic Nucleotide Levels in Swiss 3T3 Fibroblasts"
  • 265. Clementi E., Sciorati C.Nistico G., Mol. Pharm., 48, 1068 - 1077 (1995), "Growth Factor-Induced Ca2+ Responses are Differentially Modulated by Nitric Oxide via Activation of a Cyclic GMP-dependent Pathway"
  • 266. Downs S. M.Hunzicker-Dunn M., Develop. Biol., 172, 72 - 85 (1995), "Differential Regulation of Oocyte Maturation and Cumulus Expansion in the Mouse Oocyte-Cumulus Cell Complex by Site-Selective Analogs of Cyclic Adenosine Monophosphate"
  • 267. Holz G. G., Leech C. A.Habener J. F., J. Biol. Chem., 270, 17749 - 17757 (1995), "Activation of a cAMP-Regulated Ca2+-Signaling Pathway in Pancreatic Beta-Cells by the Insulinotropic Hormone Glucagon-Like Peptide-1"
  • 268. Muresan S., Bologa C., Mracec M., Chiriac A., Jastorff B., Simon Z.Naray-Szabo G., J. Mol. Struct., 342, 161 - 171 (1995), "Comparative QSAR Study with Electronic and Steric Parameters for cAMP Derivatives with Large Substituents in Positions 2, 6 and 8"
  • 269. Koumenis C., Nunez-Regueiro M., Raju U., Cook R.Eskin A., J. Biol. Chem., 270, 14619 - 14627 (1995), "Identification of Three Proteins in the Eye of Aplysia, whose Synthesis is Altered by Serotonin (5-HT)"
  • 270. Reymond C. D., Schaap P., Veron M.Williams J. G., Experientia, 51, 1166 - 1174 (1995), "Dual Role of cAMP during Dictyostelium Development"
  • 271. Scott S.-P.Tanaka J. C., Biochemistry, 34, 2338 - 2347 (1995), "Molecular Interactions of 3',5'-Cyclic Purine Analogues with the Binding Site of Retinal Rod Ion Channels"
  • 272. Vintermyr O. K., Böe R., Brustugun O. T., Maronde E., Aakvaag A.Doeskeland S. O., Endocrinology, 136, 2513 - 2520 (1995), "Cyclic Adenosine Monophosphate (cAMP) Analogs 8-Cl- and 8-NH(2)-cAMP Induce Cell Death Independently of cAMP Kinase-Mediated Inhibition of the G(1)/S Transition in Mammary Carcinoma Cells (MCF-7)"
  • 273. Cantiello H. F., Prat A. G., Reisin I. L., Ercole L. B., Abraham E. H., Amara J. F., Gregory R. J.Ausiello D. A., J. Biol. Chem., 269, 11224 - 11232 (1994), "External ATP and Its Analogs Activate the Cystic Fibrosis Transmembrane Conductance Regulator by a Cyclic AMP-independent Mechanism"
  • 274. Konda Y., Gantz I., Del Valle J., Shimoto Y., Miwa H.Yamada T., J. Biol. Chem., 269, 13162 - 13166 (1994), "Interaction of Dual Intracellular Signaling Pathways Activated by the Melanocortin-3 Receptor"
  • 275. Botella A., Delvaux M., Fioramonti J., Frexinos J.Bueno L., Peptides, 15, 637 - 643 (1994), "Galanin Induces Opposite Effects Via Different Intracellular Pathways in Smooth Muscle Cells From Dog Colon"
  • 276. Boehm S., Huck S., Koth G., Drobny H., Agneter E.Singer E. A., J. Neurochem., 63, 146 - 154 (1994), "Alpha ( 2 ) - Adrenoceptor-mediated Inhibition of Electrically Evoked [ H-3] Noradrenaline Release From Chick Sympathetic Neurons: Role of Cyclic AMP"
  • 277. Minami N., Morita K., Suemitsu T., Miyasako T.Dohi T., J. Neural Transm., 97, 65 - 72 (1994), "Cyclic AMP-induced Depolarization Measured by Bis-oxonol Fluorescence in Bovine Adrenal Medullary Chromaffin Cells"
  • 278. Shiekhattar R.Aston-Jones G., Neuroscience, 62, 523 - 529 (1994), "Activation of Adenylate Cyclase Attenuates the Hyperpolarization Following Single Action Potentials in Brain Noradrenergic Neurons Independently of Protein Kinase A"
  • 279. Li W. W., Luan S., Schreiber S. L.Assmann S. M., Plant Physiol., 106, 957 - 961 (1994), "Cyclic AMP Stimulates K+ Channel Activity in Mesophyll Cells of Vicia faba L."
  • 280. Björnsson O. G., Sparks J. D., Sparks C. E.Gibbons G. F., Eur. J. Clin. Invest., 24, 137 - 148 (1994), "Regulation of VLDL Secretion in Primary Culture of Rat Hepatocytes: Involvement of cAMP and cAMP-dependent Protein Kinases"
  • 281. Muresan S., Bologa C., Chiriac A., Jastorff B., Kurunczi L.Simon Z., Quant. Struct.-Act. Relat., 13, 242 - 248 (1994), "Comparative Structure-Affinity Relations by MTD for Binding of Cycloadenosine Monophosphate Derivatives to Protein Kinase Receptors"
  • 282. Archer S. L., Huang J. M. C., Hampl V., Nelson D. P., Schultz P. J.Weir E. K., Proc. Natl. Acad. Sci. USA, 91, 7583 - 7587 (1994), "Nitric Oxide and cGMP Cause Vasorelaxation by Activation of a Charybdotoxin-sensitive K Channel by cGMP-dependent Protein Kinase"
  • 283. Hildebrandt H., Dissertation, 0, 27 - 67 (1994), "cAMP-abhängige Proteinkinase im Antennallobus der Honigbiene: Regulation bei der Verarbeitung chemosensorischer Signale"
  • 284. Pilz R. B., Berjis M., Idriss S. D., Scheele J. S., Suhasini M., Gao L., Scheffler I. E.Boss G. R., J. Biol. Chem., 269, 32155 - 32161 (1994), "Isolation and Characterization of HL-60 Cells Resistant to Nitroprusside-Induced Differentiation"
  • 285. Sharma O. P., Flores J. A., Leong D. A.Veldhuis J. D., Endocrinology, 134, 1915 - 1923 (1994), "Cellular Basis for Follicle-Stimulating Hormone-Stimulated Calcium Signaling in Single Rat Sertoli Cells: Possible Dissociation from Effects of Adenosine 3',5'-Monophosphate"
  • 286. Cummings J., Leonard R. C. F.Miller W. R., J. Chromatogr., 658, 183 - 188 (1994), "Sensitive Determination of 8-Chloroadenosine 3',5'- Monophosphate and 8-Chloroadenosine in Plasma by High-Performance Liquid Chromatography"
  • 287. Yu L., Schaad N. C.Klein D. C., J. Neurochem., 60, 1436 - 1443 (1993), "Calcium Potentiates Cyclic AMP Stimulation of Pineal Arylalkylamine N-Acetyltransferase"
  • 288. Harvey J.Collingridge G. L., Br. J. Pharmacol., 110, 1085 - 1090 (1993), "Signal Transduction Pathways involved in the Acute Potentiation of NMDA Responses by 1S, 3R-ACPD in Rat Hippocampal Slices"
  • 289. Bakker R., Dekker K., De Jonge H. R.Groot J. A., Am. J. Physiol., 264, 362 - 368 (1993), "VIP, Serotonin, and Epinephrine Modulate the Ion Selectivity of Tight Junctions of Goldfish Intestine"
  • 290. Pinsky D., Oz M., Liao H., Morris S., Brett J., Sciacca R., Karakurum M., Van Lookeren Campagne M., Platt J., Nowygrod R., Koga S.Stern D., J. Clin. Invest., 92, 2994 - 3002 (1993), "Restoration of the cAMP Second Messenger Pathway Enhances Cardiac Preservation for Transplantation in a Heterotopic Rat Model"
  • 291. Ohmura E., Wakai K., Isozaki O., Murakami H., Onoda N., Emoto N., Shizume K., Tsushima T., Demura H.Robins R. K., Br. J. Cancer, 67, 279 - 283 (1993), "Inhibition of Human Pancreatic Cancer Cell (MIA PaCa-2) Growth by Cholera Toxin and 8-Chloro-cAMP in vitro"
  • 292. Rawlings S. R., Canny B. J.Leong D. A., Endocrinology, 132, 1447 - 1452 (1993), "Pituitary Adenylate Cyclase- Activating Polypeptide Regulates Cytosolic Ca2+ in Rat Gonadotropes and Somatotropes through Different Intracellular Mechanisms"
  • 293. Bologa C., Muresan S., Liauw S., Iwitzki F.Chiriac A., Anal. Univ. Timisoara, 2, 27 - 36 (1993), "Quantitative Structure-Activity Study by the MTD-Method for cAMP-Derivatives with Large Substituents in Positions 2 and 8"
  • 294. Naß N., Colling C., Cramer M., Genieser H.-G., Butt E., Winkler E., Jaenicke L.Jastorff B., Biochem. J., 285, 129 - 136 (1992), "Mapping of the Epitope/Paratope Interactions of a Monoclonal Antibody Directed Against Adenosine- 3', 5'- monophosphate"
  • 295. Haynes J., Robinson J., Saunders L., Taylor A. E.Strada S. J., Am. J. Physiol., 262, 511 - 516 (1992), "Role of cAMP-dependent Protein Kinase in cAMP-mediated Vasodilation"
  • 296. Johnson R. L., Van Haastert P. J. M., Kimmel A. R., Saxe III C. L., Jastorff B.Devreotes P. N., J. Biol. Chem., 267, 4600 - 4607 (1992), "The Cyclic Nucleotide Specificity of Three cAMP Receptors in Dictyostelium"
  • 297. Furumichi T., Yamada Y., Suzuki T., Furui H., Yamauchi K.Saito H., Jpn. Heart J., 33, 373 - 382 (1992), "Adenosine 3', 5' - Cyclic Monophosphate Inhibits In Vitro Angiogenesis Induced by Endothelial Cell Growth Factor"
  • 298. Ishizuka J., Beauchamp R. D., Townsend C. M., Greeley G. H.Thompson J. C., J. Cell. Physiol., 150, 1 - 7 (1992), "Receptor-mediated Autocrine Growth-stimulatory Effect of 5-Hydroxytryptamine on Cultured Human Pancreatic Carcinoid Cells"
  • 299. Connolly B. J., Willits P. B., Warrington B. H.Murray K. J., Biochem. Pharmacol., 44, 2303 - 2306 (1992), "8-(4-Chlorophenyl)thio-cyclic AMP is a Potent Inhibitor of the cyclic GMP-specific Phosphodiesterase (PDEV )"
  • 300. Nishio K., Morikage T., Kubota N., Ohmori T., Takeda Y., Fujiwara Y., Miki K., Abe K.Saijo N., Jpn. J. Cancer Res., 83, 754 - 60 (1992), "Alteration of Type II Regulatory Subunit of cAMP-dependent Protein Kinase in Human Cisplatin-Resistant Cells as a Basis of Collateral Sensivity to 8-chloro-cAMP"
  • 301. Skalhegg B. S., Landmark B. F., Doeskeland S. O., Hansson V., Lea T.Jahnsen T., J. Biol. Chem., 267, 15707 - 15714 (1992), "Cyclic AMP-dependent Protein Kinase Type I Mediates the Inhibitory Effects of 3', 5'-Cyclic Adenosine Monophosphate on Cell Replication in Human T Lymphocytes"
  • 302. Szücs K., Sagi G.Vereb G., Int. J. Biochem., 24, 915 - 921 (1992), "Effect of Some New cAMP Analogs on cAMP-Dependent Protein Kinase Isoenzymes"
  • 303. Doeskeland S. O., Boe R., Bruland T., Vintermyr O. K., Jastorff B.Lanotte M., Method. Surveys Biochem. & Anal., E. Reid et al. (eds.). Royal Society Chem. Cambridge UK , Redwood Press Ltd., 21, 103 - 114 (1991), "Criteria Used to Judge That a Cellular Response is Mediated by Cyclic AMP"
  • 304. Van Ments-Cohen M., Genieser H.-G., Jastorff B., Van Haastert P. J. M.Schaap P., FEMS Microbiol. Lett., 82, 9 - 14 (1991), "Kinetics and Nucleotide Specificity of a Surface cAMP Binding Site in Dictyostelium discoideum, which is not Down-regulated by cAMP"
  • 305. Desarmenien M. G.Spitzer N. C., Neuron, 7, 797 - 805 (1991), "Role of Calcium and Protein Kinase C in Development of the Delayed Rectifier Potassium Current in Xenopus Spinal Neurons"
  • 306. Sandberg M., Butt E., Nolte C., Fischer L., Halbrügge M., Beltmann J., Jahnsen T., Genieser H.-G., Jastorff B.Walter U., Biochem. J., 279, 521 - 527 (1991), "Characterization of Sp- 5, 6- dichloro-1-ß-D-ribofuranosylbenzimidazole- 3',5'- monophosphorothioate (Sp-5,6-DCl-cBIMPS) as a Potent and Specific Activator of cyclic AMP- dependent Protein Kinase in Cell Extracts and Intact Cells"
  • 307. Lanotte M., Riviere J. B., Hermouet S., Houge G., Vintermyr O. K., Gjertsen B. T.Doeskeland S. O., J. Cell. Physiol., 146, 73 - 80 (1991), "Programmed Cell Death (Apoptosis) Is Induced Rapidly and With Positive Cooperativity by Activation of Cyclic Adenosine Monophosphate-Kinase I in a Myeloid Leukemia Cell Line"
  • 308. Van Lookeren Campagne M. M., Diaz F. V., Jastorff B.Kessin R. H., Cancer Res., 51, 1600 - 1605 (1991), "8-Chloroadenosine 3',5'-Monophosphate Inhibits the Growth of Chinese Hamster Ovary and Molt-4 Cells Through its Adenosine Metabolite"
  • 309. Shabb J. B., Buzzeo B. D., Ng L.Corbin J. D., J. Biol. Chem., 266, 24320 - 24326 (1991), "Mutating Protein Kinase cAMP-binding Sites into cGMP-binding Sites"
  • 310. Peters D. J. M., Bominaar A. A., Snaar-Jagalska B. E., Brandt R., Van Haastert P. J. M., Ceccarelli A., Williams J. G.Schaap P., Proc. Natl. Acad. Sci. USA, 88, 9219 - 9223 (1991), "Selective Induction of Gene Expression and Second-Messenger Accumulation in Dictyostelium Discoideum by the Partial Chemotactic Antagonist 8-p-chlorophenylthioadenosine 3´,5´-cyclic Monophosphate"
  • 311. Van Lookeren Campagne M. M., Diaz F. V., Jastorff B., Winkler E., Genieser H.-G.Kessin R. W., J. Biol. Chem., 265, 5847 - 5854 (1990), "Characterization of the Yeast Low Km cAMP- Phosphodiesterase With cAMP Analogues"
  • 312. Cho-Chung Y. S., Cancer Res., 50, 7093 - 7100 (1990), "Role of Cyclic AMP Receptor Proteins in Growth, Differentiation, and Suppression of Malignancy: New Approaches to Therapy"
  • 313. Hei Y.-J., MacDonell K. L., McNeill J. H.Diamond J., Mol. Pharmacol., 39, 233 - 238 (1990), "Lack of Correlation Between Activation of Cyclic AMP-Dependent Protein Kinase and Inhibition of Contraction of Rat Vas Deferens by Cyclic AMP Analogs"
  • 314. Oegreid D., Ekanger R., Suva R. H., Miller J. P.Doeskeland S. O., Eur. J. Biochem., 181, 19 - 31 (1989), "Comparison of the Two Classes of Binding Sites ( A and B ) of Type I and Type II Cyclic AMP-dependent Protein Kinases Using Cyclic Nucleotide Analogs"
  • 315. Eskin A., Garcia K. S.Byrne J. H., Proc. Natl. Acad. Sci. USA, 86, 2458 - 2462 (1989), "Information Storage in the Nervous System of Aplysia: Specific Proteins Affected by Serotonin and cAMP"
  • 316. Shanahan M. F.Edwards B. M., Endocrinology, 125, 1074 - 1081 (1989), "Stimulation of Glucose Transport in Rat Cardiac Myocytes by Guanosine-3',5'-Cyclic-Monophosphate"
  • 317. Erneux C.Miot F., Methods Enzymol., 159, 520 - 530 (1988), "Cyclic Nucleotide Analogs Used to Study Phosphodiesterase Catalytic and Allosteric Sites"
  • 318. Francis S. H., Noblett B. D., Todd B. W., Wells J. N.Corbin J. D., Mol. Pharmacol., 34, 506 - 517 (1988), "Relaxation of Vascular and Tracheal Smooth Muscle by Cyclic Nucleotide Analogs That Preferentially Activate Purified cGMP-Dependent Protein Kinase"
  • 319. Tortora G., Tagliaferri P., Clair T., Colamonici O., Neckers L. M., Robins R. K.Cho-Chung J.-S., Blood, 71, 230 - 233 (1988), "Site-selective Cyclic AMP Analogs at Micromolar Concentrations Induce Growth Arrest and Differentiation of Acute Promyelocytic, Chronic Myelocytic, and Acute Lymphocytic Human Leukemia Cell Lines"
  • 320. Tagliaferri P., Katsaros D., Clair T., Ally S., Tortora G., Neckers L. M., Rubalcava B., Parandoosh Z., Chang Y.-A., Revankar G. R., Crabtree G. W., Robins R. K.Cho-Chung Y. S., Cancer Res., 48, 1642 - 1650 (1988), "Synergistic Inhibition of Growth of Breast and Colon Human Cancer Cell Lines by Site-selective Cyclic AMP Analogs"
  • 321. Oegreid D., Doeskeland S. O., Gorman K. B.Steinberg R. A., J. Biol. Chem., 263, 17397 - 17404 (1988), "Mutations That Prevent Cyclic Nucleotide Binding to Binding Sites A or B of Type I Cyclic AMP- dependent Protein Kinase"
  • 322. Beebe S. J., Beasley-Leach A.Corbin J. D., Methods Enzymol., 159, 531 - 540 (1988), "cAMP Analogs Used to Study Low-km, Hormone-sensitive Phosphodiesterase"
  • 323. Gronenborn A. M., Sandulache R., Gärtner S.Clore G. M., Biochem. J., 253, 801 - 807 (1988), "Mutations in the Cyclic AMP Binding Site of the Cyclic AMP Receptor Protein of Escherichia coli"
  • 324. Richter-Landsberg C.Jastorff B., NATO ASI Ser. (Glial- Neur. Commun. Dev. Regener.), 2, 339 - 354 (1987), "Effect of Nerve Growth Factor and cAMP Analogs on Neuronal Differentiation in PC12 Cells: Studies with an Inhibitor of cAMP- Dependent Protein Kinases"
  • 325. Katsaros D., Tortora G., Tagliaferri P., Clair T., Ally S., Neckers L. M., Robins R. K.Cho-Chung Y. S., FEBS Lett., 223, 97 - 103 (1987), "Site-selective Cyclic AMP Analogs Provide a New Approach in the Control of Cancer Cell Growth"
  • 326. Clair T., Ally S., Tagliaferri P., Robins R. K.Cho-Chung Y. S., FEBS Lett., 224, 377 - 384 (1987), "Site-selective Cyclic AMP Analogs Induce Nuclear Translocation of the RII cAMP Receptor Protein in Ha-MuSV-Transformed NIH/3T3 Cells"
  • 327. Gilbard J. P.Dartt D. A., Eur. Pat. Appl. EP 234854 A2 Appl. 87/301403 US Appl. 830997, 27, 0 - 0 (1987), "Preparations For Stimulation of Tear Secretion With Phosphodiesterase Inhibitors and Cyclic Nucleotide Analogues"
  • 328. Erneux C., Van Sande J., Jastorff B.Dumont J. E., Biochem. J., 234, 193 - 197 (1986), "Modulation of Cyclic AMP Action in the Dog Thyroid by its Agonist and Antagonist Sp-and Rp- Adenosine-3',5'-Monophosphorothioate"
  • 329. Theibert A., Palmisano M., Jastorff B.Devreotes P. N., Develop. Biol., 114, 529 - 533 (1986), "The Specificity of the cAMP Receptor Mediating Activation of Adenylate Cyclase in Dictyostelium Discoideum"
  • 330. Brandt C., Jastorff B.Hildebrandt A., Roux's Arch. Dev. Biol., 195, 276 - 280 (1986), "Sporulation Delay by Stable cAMP Analogs in the Slime Mould Physarum Polycephalum"
  • 331. Corbin J. D., Oegreid D., Miller J. P., Suva R. H., Jastorff B.Doeskeland S. O., J. Biol. Chem., 261, 1208 - 1214 (1986), "Studies of cGMP Analog Specificity and Function of the Two Intrasubunit Binding Sites of cGMP-dependent Protein Kinase"
  • 332. Braumann T.Jastorff B., J. Chromatogr., 350, 105 - 118 (1985), "Physicochemical Characterization of Cyclic Nucleotides by Reversed Phase High-Performance Liquid Chromatography. II. Quantitative Determination of Hydrophobicity"
  • 333. Corbin J. D., Beebe S. J.Blackmore P. F., J. Biol. Chem., 260, 8731 - 8735 (1985), "cAMP-dependent Protein Kinase Activation Lowers Hepatocyte cAMP"
  • 334. Scholübbers H.-G., Van Knippenberg P. H., Baraniak J., Stec W. J., Morr M.Jastorff B., Eur. J. Biochem., 138, 101 - 109 (1984), "Investigations on Stimulation of Lac Transciption in Vivo in Escherichia Coli by cAMP Analogs"
  • 335. Beebe S. J., Holloway R., Rannels S. R.Corbin J. D., J. Biol. Chem., 259, 3539 - 3547 (1984), "Two Classes of cAMP Analogs Which Are Selective for the Two Different cAMP-binding Sites of Type II Protein Kinase Demonstrate Synergism When Added Together to Intact Adipocytes"
  • 336. Coulson R., Baraniak J., Stec W. J.Jastorff B., Life Sci., 32, 1489 - 1498 (1983), "Transport and Metabolism of N6- and C8- Substituted Analogs of Adenosine 3',5'-Cyclic Monophosphate and Adenosine 3',5'-Cyclic Phosphorothioate by the Isolated Perfused Rat Kidney"
  • 337. Van Haastert P. J. M.Kien E., J. Biol. Chem., 258, 9636 - 9642 (1983), "Binding of cAMP Derivatives to Dictyostelium Discoideum Cells. Activation Mechanism of the Cell Surface cAMP Receptor"
  • 338. Van Haastert P. J. M., J. Biol. Chem., 258, 9643 - 9648 (1983), "Binding of cAMP and Adenosine Derivatives to Dictyostelium Discoideum Cells. Relationship of Binding, Chemotactic and Antagonistic Activities"
  • 339. Oegreid D., Doeskeland S. O.Miller J. P., J. Biol. Chem., 258, 1041 - 1049 (1983), "Evidence That Cyclic Nucleotides Activating Rabbit Muscle Protein Kinase I Interact with Both Types of cAMP Binding Sites Associated with the Enzyme"
  • 340. Robinson-Steiner A. M.Corbin J. D., J. Biol. Chem., 258, 1032 - 1040 (1983), "Probable Involvement of Both Intrachain cAMP Binding Sites in Activation of Protein Kinase"
  • 341. Van Haastert P. J. M., Jastorff B., Pinas J. E.Konijn T. M., J. Bacteriol., 149, 99 - 105 (1982), "Analogs of Cyclic AMP as Chemoattractants and Inhibitors of Dictyostelium Chemotaxis"
  • 342. Gronenborn A. M.Clore G. M., Biochemistry, 21, 4040 - 4048 (1982), "Proton Nuclear Magnetic Resonance Studies on Cyclic Nucleotide Binding to the Escherichia coli Adenosine Cyclic 3',5'- Phosphate Receptor Protein"
  • 343. de Wit R. J. W., Arents J. C.Van Driel R., FEBS Lett., 145, 150 - 154 (1982), "Ligand Binding Properties of the Cytoplasmic cAMP-Binding Protein of Dictyostelium discoideum"
  • 344. Jastorff B., in: Cell Regulation by Intracellular Signal Molecules St. Swillens ed. 195 - 207 Plenum Press New York London, 0, 0 - 0 (1982), "The Effects of cyclic Nucleotide Derivatives on Cell Metabolism"
  • 345. de Wit R. J. W., Hoppe J., Stec W. J., Baraniak J.Jastorff B., Eur. J. Biochem., 122, 95 - 99 (1982), "Interaction of cAMP Derivatives with the 'Stable' cAMP-Binding Site in the cAMP-Dependent Protein Kinase Type I"
  • 346. Varughese K. I., Lu C. T.Kartha G., J. Am. Chem. Soc., 104, 3398 - 3401 (1982), "The Crystal and Molecular Structure of Cyclic Adenosine 3', 5'- Monophosphate Sodium Salt, Monoclinic Form"
  • 347. Rapoport R. M., Draznin M. B.Murad F., Proc. Natl. Acad. Sci. USA, 79, 6470 - 6474 (1982), "Sodium Nitroprusside-induced Protein Phosphorylation in Intact Rat Aorta is Mimicked by 8-Bromo Cyclic GMP"
  • 348. Donnelly T. E.Barron B., Biochim. Biophys. Acta, 657, 168 - 178 (1981), "Effects of Divalent Metals on the Specificity of Inhibitors of the Cyclic Nucleotide Phosphodiesterases from Bovine Heart"
  • 349. Miller J. P., Adv. Cyclic Nucl. Res., 14, 335 - 344 (1981), "Cyclic AMP Derivatives as Tools for Mapping Cyclic AMP Binding Sites of Cyclic AMP-dependent Protein Kinases I and II"
  • 350. Erneux C., Couchie D., Dumont J. E., Baraniak J., Stec W. J., Garcia Abbad E., Petridis G.Jastorff B., Eur. J. Biochem., 115, 503 - 510 (1981), "Specificity of cyclic GMP Activation of a Multi-substrate Cyclic Nucleotide Phosphodiesterase from Rat Liver"
  • 351. Miller J. P., Boswell K. H., Meyer R. B., Christensen L. F.Robins R. K., J. Med. Chem., 23, 242 - 251 (1980), "Synthesis and Enzymatic and Inotropic Activity of Some New 8-Substituted and 6,8-Disubstituted Derivatives of Adenosine Cyclic 3',5- Monophosphate"
  • 352. Yagura T. S.Miller J. P., Biochim. Biophys. Acta, 630, 463 - 467 (1980), "Activation of Type I and Type II Cyclic AMP-dependent Protein Kinases by 2,8-disubstituted Derivatives of Cyclic AMP"
  • 353. Rannels S. R.Corbin J. D., J. Biol. Chem., 255, 7085 - 7088 (1980), "Two Different Intrachain cAMP Binding Sites of cAMP-Dependent Protein Kinases"
  • 354. Czarnecki J., Geahlen R.Haley B. E., Methods Enzymol., 56, 642 - 653 (1979), "Synthesis and Use of Azido Photoaffinity Analogs of Adenine and Guanine Nucleotides"
  • 355. Niles R. M., Ludwig K. W.Makarski J. S., J. Natl. Cancer Inst., 63, 909 - 911 (1979), "Differential Growth Inhibition in Two Human Carcinoma Cell Lines by Cyclic Adenosine 5'-Monophosphate Analogs"
  • 356. Jastorff B., Hoppe J., Mato J. M.Konijn T. M., in Molecular Mechanisms of Biological Recognition Ed.) Elsevier North-Holland Biomedical Press, 0, 107 - 117 (1979), "Ligand Analogs - A Tool for the Elucidation of Protein-Ligand Interactions. Model System: cAMP"
  • 357. Higashio T., Abe Y., Miyazaki M.Yamamoto K., Experientia, 36, 234 - 236 (1979), "Renal Effects of 8-substituted Derivatives of Adenosine 3',5'-cyclic Monophosphate in Dogs"
  • 358. Nishikori K.Maeno H., J. Biol. Chem., 254, 6099 - 6109 (1979), "Close Relationship between Adenosine 3',5'-Monophosphate-dependent Endogenous Phosphorylation of a Specific Protein and Stimulation of Calcium Uptake in Rat Uterine Microsomes"
  • 359. Jastorff B., Hoppe J., Mato J.Konijn T. M., Nucl. Acids Res., 4, 237 - 241 (1978), "Comparison of the Chemical Interactions of cAMP at its Binding Sites of Protein Kinase Type I from Rabbit Muscle and the Cellular Slime Mould Dictyostelium Discoideum"
  • 360. O'Neill J. P., Li A. P.Hsie A. W., BBA, 497, 35 - 45 (1977), "Action of Cyclic Nucleotide Analogues in Chinese Hamster Ovary Cells"
  • 361. Dills W. L., Beavo J. A., Bechtel P. J., Myers K. R., Sakai L. J.Krebs E. G., Biochemistry, 15, 3724 - 3731 (1976), "Binding of Adenosine 3', 5'- Monophosphate Dependent Protein Kinase Regulatory Subunit to Immobilized Cyclic Nucleotide Derivatives"
  • 362. Sasaki Y., Suzuki N., Sowa T., Nozawa R.Yokota T., Biochemistry, 15, 1408 - 1413 (1976), "Effects of 8-Substituted Adenosine 3',5'-monophosphate Derivatives on High Km Phosphodiesterase Activity"
  • 363. Keeler E. K.Campbell P., Biochem. Biophys. Res. Comm., 72, 575 - 580 (1976), "A Fluorescent Photo-Affinity Label for Cyclic AMP Binding Proteins"
  • 364. Naka T.Honjo M., Chem. Pharm. Bull., 24, 2052 - 2056 (1976), "Synthesis of 8-Carbamoyl- and 8-Carboxyadenosine 3', 5'-Cyclic Phosphates"
  • 365. Miller J. P., Beck A. H., Simon L. N.Meyer R. B., J. Biol. Chem., 250, 426 - 431 (1975), "Induction of Hepatic Tyrosine Aminotransferase in Vivo by Derivatives of Cyclic Adenosine 3',5'- Monophosphate"
  • 366. Siggins G. R.Henriksen S. J., Science, 189, 559 - 560 (1975), "Analogs of Cyclic Adenosine Monophosphate: Correlation of Inhibition of Purkinje Neurons with Protein Kinase Activation"
  • 367. Meyer R. B.Miller J. P., Life Sci., 14, 1019 - 1040 (1974), "Analogs of Cyclic AMP and Cyclic GMP: General Methods of Synthesis and the Relationship of Structure to Enzymatic Activity"
  • 368. Muneyama K., Shuman D. A., Boswell K. H., Robins R. K., Simon L. N.Miller J., J. Carbohydr. Nucleosides Nucleotides, 1, 55 - 60 (1974), "Synthesis and Biological Activity of 8-Haloadenosine 3', 5'- Cyclic Phosphates"
  • 369. Jastorff B.Freist W., Bioorg. Chem., 3, 103 - 113 (1974), "Synthesis and Biological Activities of cyclic AMP Analogs Modified in the 1, 2 and 2'- Positions"
  • 370. Kuo J. F., Miyamoto E.Reyes P. L., Biochem. Pharmacol., 23, 2011 - 2021 (1974), "Activation and Dissociation of Adenosine 3', 5'- Monophosphate-dependent and Guanosine 3', 5'- monophosphate-dependent Protein Kinases by Various Cyclic Nucleotide Analogs"
  • 371. Nelböck M., Michal G.Weimann G., Pure Appl. Chem., 35, 411 - 437 (1973), "Analogues of Cyclic AMP and their Physiological Response"
  • 372. Anderson W. B., Perlman R. L.Pastan I., J. Biol. Chem., 247, 2717 - 2722 (1972), "Effect of Adenosine 3', 5'- Monophosphate Analogues on the Activity of the Cyclic Adenosine 3', 5'- Monophosphate Receptor in Escherichia coli"
  • 373. Du Plooy M., Michal G., Weimann G., Nelboeck M.Paoletti R., Biochim. Biophys. Acta, 230, 30 - 39 (1971), "Cyclophosphates I. Effect of Various Cyclophosphates on Phosphorylase b Kinase Activation"
  • 374. Muneyama K., Bauer R. J., Shuman D. A., Robins R. K.Simon L. N., Biochemistry, 10, 2390 - 2395 (1971), "Chemical Synthesis and Biological Activity of 8-Substituted Adenosine 3',5'- Cyclic Monophosphate Derivatives"
  • 375. Free C. A., Chasin M., Paik V. S.Hess S. M., Biochemistry, 10, 3785 - 3789 (1971), "Steroidogenic and Lipolytic Activities of 8-Substituted Derivatives of Cyclic 3',5'-Adenosine Monophosphate"
  • 376. Posternak T.Cehovic G., Ann. New York Acad. Sci., 185, 42 - 49 (1971), "Derivatives and Analogues of Cyclic Nucleotides"
  • 377. Michal G., Nelböck M.Weimann G., Z. Anal. Chem., 252, 189 - 193 (1970), "Cyclophosphate III. Spaltung Verschiedener Cyclophosphate durch Phosphodiesterase aus Herz und Fettgewebe"

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