For other salt forms please inquire.c[G(2',5')pA(3',5')p] was found to be the metazoan second messenger produced by the mammalian innate immune DNA sensor cGAMP synthase (cGAS). It has also been reported to exert potent activation of the immune signalling protein STING. Detailed technical information available. References: Gao et al., Cell, 153, 1094 - 1107 (2013); Ablasser et al., Nature, 498, 380 - 384 (2013); Zhang et al., Mol. Cell, 51, 226 - 235 (2013); Diner et al., Cell Rep., 3, 1355 - 1361 (2013).
Related products: Biolog also offers the potential bacterial second messenger c[G(3',5')pA(3',5')p] (c-(ApGp), Cat. No. C 117).
Cat. No. | C 161 |
CAS number | [1441190-66-4] |
Purity | > 98% HPLC |
Salt form | Sodium |
Storage temperature | -20°C / -4°F |
Molecular formula | C₂₀H₂₄N₁₀O₁₃P₂ (free acid) |
Molecular weight [g/mol] | 674.4 (free acid) |
Absorption max [nm] | 256 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 25050 |