c[A(2',5')pG(2',5')p] is a cyclic dinucleotide structurally related to the metazoan second messenger and STING activator c[G(2',5')pA(3',5')p] (2'3'-cGAMP, Cat. No. C 161). Similar to natural c[G(2',5')pA(3',5')p], c[A(2',5')pG(2',5')p] binds the signalling protein STING and subsequently induces type I interferons. Detailed technical information available. References: Gao et al., Cell, 154, 748 - 762 (2013); Zhang et al., Mol. Cell, 51, 226 - 235 (2013).
Cat. No. | C 210 |
CAS number | [1465774-27-9] |
Purity | > 98% HPLC |
Salt form | Sodium |
Storage temperature | -20°C / -4°F |
Molecular formula | C₂₀H₂₄N₁₀O₁₃P₂ (free acid) |
Molecular weight [g/mol] | 674.4 (free acid) |
Absorption max [nm] | 256 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 25050 |