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c-(ApGp) / 3'3'-cGAMP

Cyclic (adenosine monophosphate- guanosine monophosphate) ( c-(ApGp) / 3'3'-cGAMP / c[A(3',5')pG(3',5')p] / c[G(3',5')pA(3',5')p] ), sodium salt
Bacterial second messenger
Cat. No.: C 117
    
CAS No.: [849214-04-6]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: C 117-005
Unit: 0.5 µmol / ~337 µg
$110.00

For other salt forms please inquire. Analogue of the bacterial second messengers c-diAMP (Cat. No. C 088) and c-diGMP (Cat. No. C 057). c-(ApGp) is considered to play a role in Vibrio cholerae pathogenesis and was also reported to stimulate the production of interferon via STING. Detailed technical information available. References: Davies et al., Cell, 149, 358 - 370 (2012); Wu et al., Science339, 826 - 830 (2013).

Related products: Biolog also offers the metazoan cyclic dinucleotide second messenger c[G(2',5')pA(3',5')p] which contains two distinct phosphodiester linkages (Cat. No. C 161).

Cat. No. C 117
CAS number [849214-04-6]
Purity > 98% HPLC (typically > 99%)
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₂₀H₂₄N₁₀O₁₃P₂ (free acid)
Molecular weight [g/mol] 674.4 (free acid)
Absorption max [nm] 256
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 25050