Membrane-permeant precursor of the PKA activator 8-Cl-cAMP (Cat. No. C 007). Metabolic activation by esterases releases the polar active analogue, which is trapped inside the cell. Detailed technical information available. Reference: J. Kruppa, Ph.D. thesis, University of Bremen, Germany, 1996. Biolog also offers Phosphate tris(acetoxymethyl)ester (PO4-AM3, Cat. No. P 030) which is recommended as control reagent in nucleotide-AM ester applications.
|Cat. No.||C 050|
|Purity||> 97% HPLC for mixture of isomers|
|Storage temperature||-20°C / -4°F|
|Molecular weight [g/mol]||435.7|
|Target||PKA (cAK) Activator|
|Absorption max [nm]||262|
|Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]||17000|