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PO₄-AM₃

Phosphate tris(acetoxymethyl)ester ( PO₄-AM₃ )
Control reagent for nucleotide-AM ester applications
Cat. No.: P 030
    
CAS No.: [148334-61-6]
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Product Name Price (net) Qty
Cat. No.: P 030-003
Unit: 0.33 µmol / ~0.1 mg
$62.00

Membrane-permeant prodrug of inorganic phosphate. PO4-AM3 is recommended as control reagent in nucleotide-AM ester applications to test for side effects of acetic acid and formaldehyde. After permeation and intracellular metabolic activation by endogenous esterases the highly polar inorganic phosphate (PO43-) is released. In addition, the AM ester groups liberate acetic acid and formaldehyde, two metabolites with potential biological functions. References: Schultz et al., J. Biol. Chem., 268, 6316 - 6322 (1993); Chepurny et al., J. Biol. Chem., 284, 10728 - 10736 (2009).

 

Please note: 0.33 μmol of PO4-AM3 is stoichiometrically equivalent to 1 μmol of a cyclic nucleotide AM ester. 

Cat. No. P 030
CAS number [148334-61-6]
Purity > 95% (MS)
Storage temperature -20°C / -4°F
Molecular formula C₉H₁₅O₁₀P
Molecular weight [g/mol] 314.2