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Alternative structural projections:

6-MAH-cAMP

N6- (6- [N- Methylanthraniloyl]hexylamino)adenosine-3', 5'-monophosphate ( 6-MAH-cAMP ), sodium salt

Fluorescent cyclic AMP analogue
Cat. No.: M 017
    
CAS No.: [723313-27-7]
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Product Name Price (net) Qty
Cat. No.: M 017-05
Unit: 5 µmol / ~2.9 mg
$139.00
Fluorescent, membrane- permeant cyclic AMP analogue (λexc 333 nm, λem 437). Detailed technical information available. References: Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001); Moll et al., J. Neural. Transm., 113, 1015 - 1032 (2006). For modifications with the methylanthraniloyl group please compare: Theyssen, J. Mol. Biol., 263, 657 - 670 (1996).
Cat. No. M 017
CAS number [723313-27-7]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₂₄H₃₁N₇O₇P · Na
Molecular weight [g/mol] 583.5
Target PKA (cAK) Activator
Excitation max [nm] 333
Emission max [nm] 437
Lipophilicity 2.98
Absorption max [nm] 261
  • 1. Schweinsberg S., Moll D., Burghardt N. C., Hahnefeld C., Schwede F., Zimmermann B., Drewianka S., Werner L., Kleinjung F., Genieser H.-G., Schuchhardt J.Herberg F. W., Proteomics, 8, 1212 - 1220 (2008), "Systematic interpretation of cyclic nucleotide binding studies using KinetXBase"
  • 2. Wang J. L., Guo J.-X., Zhang Q.-Y., Wu J. J.-Q., Seifert R.Lushington G. H., Bioorg. Med. Chem., 15, 2993 - 3002 (2007), "A Conformational Transition in the Adenylyl Cyclase Catalytic Site Yields Different Binding Modes for Ribosyl-modified and Unmodified Nucleotide Inhibitors"
  • 3. Hahnefeld C.Herberg F. W., Abstract of the 13th Protein Kinase Symposium p. 14, 0, 12 - 15 (2002), "cAMP-dependent Protein Kinase: cAMP Analog Screening Using Surface Plasmon Resonance and Fluorescent Methods"
  • 4. Kraemer A., Rehmann H., Cool R. H., Theiss C., de Rooij J., Bos H.Wittinghofer A., J. Mol. Biol., 306, 1167 - 1177 (2001), "Dynamic Interaction of cAMP with the Rap Guanine-nucleotide Exchange Factor Epac1"
  • 5. Theyssen H., Schuster H. P., Packschies L., Bukau B.Reinstein J., J. Mol. Biol., 263, 657 - 670 (1996), "The Second Step of ATP Binding to DnaK Induces Peptide Release"