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Alternative structural projections:

8-MABA-cAMP

8- (4- [N- Methylanthraniloyl]aminobutylamino) adenosine- 3', 5'- monophosphate ( 8-MABA-cAMP ), sodium salt
Fluorescent cAMP analogue
Cat. No.: M 016
    
CAS No.: [909782-76-9]
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Product Name Price (net) Qty
Cat. No.: M 016-05
Unit: 5 µmol / ~2.9 mg
$114.00
Fluorescent, membrane- permeant cyclic AMP analogue (λexc 352 nm, λem 436 nm). Detailed technical information available. Reference: Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001).
Cat. No. M 016
CAS number [909782-76-9]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₂₂H₂₈N₈O₇P · Na
Molecular weight [g/mol] 570,5
Modifications 8-cAMP
Target PKA (cAK) Activator
Excitation max [nm] 352
Emission max [nm] 436
Lipophilicity 2.45
Absorption max [nm] 261 / 278
  • 1. Schweinsberg S., Moll D., Burghardt N. C., Hahnefeld C., Schwede F., Zimmermann B., Drewianka S., Werner L., Kleinjung F., Genieser H.-G., Schuchhardt J.Herberg F. W., Proteomics, 8, 1212 - 1220 (2008), "Systematic interpretation of cyclic nucleotide binding studies using KinetXBase"
  • 2. Dao K. K., Teigen K., Kopperud R. K., Hodneland E., Schwede F., Christensen A. E., Martinez A.Doeskeland S. O., J. Biol. Chem., 281, 21500 - 21511 (2006), "Epac1 and cAMP-dependent Protein Kinase Holoenzyme Have Similar cAMP Affinity, but Their cAMP Domains Have Distinct Structural Features and Cyclic Nucleotide Recognition"
  • 3. Kraemer A., Rehmann H., Cool R. H., Theiss C., de Rooij J., Bos H.Wittinghofer A., J. Mol. Biol., 306, 1167 - 1177 (2001), "Dynamic Interaction of cAMP with the Rap Guanine-nucleotide Exchange Factor Epac1"