The second messenger cyclic AMP immobilized on agarose by an aminoethyl spacer attached to position 6 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is also offered with a longer spacer (6-AH-cAMP-Agarose, Cat. No. A 036) and as a PDE-resistant version (Sp-6-AE-cAMPS-Agarose, Cat. No. A 109). Detailed technical information available. Reference: Murashima et al., Biochemistry, 29, 5285 - 5292 (1990).
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
|Cat. No.||A 111|
|Storage temperature||4°C / 39°F|