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Alternative structural projections:


N6- (2- Aminoethyl)adenosine- 3', 5'- cyclic monophosphate, immobilized on agarose ( 6-AE-cAMP-Agarose )

cyclic AMP immobilized on agarose
Cat. No.: A 111
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 111-06
Unit: 0.6 ml
Cat. No.: A 111-25
Unit: 2.5 ml
Cat. No.: A 111-60
Unit: 6 ml

The second messenger cyclic AMP immobilized on agarose by an aminoethyl spacer attached to position 6 of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. This ligand is also offered with a longer spacer  (6-AH-cAMP-Agarose, Cat. No. A 036) and as a PDE-resistant version (Sp-6-AE-cAMPS-Agarose, Cat. No. A 109). Detailed technical information available. Reference: Murashima et al., Biochemistry, 29, 5285 - 5292 (1990).

Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.


Appearance: Suspension in 30 mM Na2HPO4 buffer (pH 7).

Cat. No. A 111
CAS number [pending]
Appearance Suspension in 30 mM Na₂HPO₄ buffer (pH 7)
Storage temperature 4°C / 39°F
Modifications 6-cAMP
  • 1. Hanke S. E., Bertinetti D., Badel A., Schweinsberg S., Genieser H.-G.Herberg F. W., N. Biotechnol., 28, 294 - 301 (2011), "Cyclic Nucleotides as Affinity Tools: Phosphorothioate cAMP Analogues Adress Specific PKA Subproteomes"
  • 2. Murashima S., Tanaka T., Hockman S.Manganiello V. C., Biochemistry, 29, 5285 - 5292 (1990), "Characterization of particulate cyclic nucleotide phosphodiesterases from bovine brain: Purification of a distinct cGMP-Stimulated Isoenzyme"