For other salt forms or analogues please inquire. Up4A is a dinucleoside polyphosphate containing both, a purine as well as a pyrimidine nucleobase moiety. Purinoceptor agonist and potent endothelial-derived contracting factor. Detailed technical information and references available. Reference: Jankowski et al., Nature Medicine, 11, 223 - 227 (2005).
| Cat. No. | U 008 |
| CAS number | [10527-48-7] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₉H₂₇N₇O₂₁P₄ (free acid) |
| Molecular weight [g/mol] | 813.4 (free acid) |
| Absorption max [nm] | 260 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 22700 |
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- 6. Jankowski V., Meyer A.-A., Schlattmann P., Gui Y., Zheng X.-l., Stamcou I., Radtke K., Tran T. N. A., van der Giet M., Tölle M., Zidek W.Jankowski J., Arterioscler. Thromb. Vasc. Biol., 27, 1776 - 1781 (2007), "Increased Uridine Adenosine Tetraphosphate Concentrations in Plasma of Juvenile Hypertensives"
- 7. Leite R., Linder F. F. P., Linder E.Webb R. C., FASEB J. A1185, 20, 0 - 0 (2006), "Uridine Adenosine Tetraphosphate-induced Contraction is Modulated by the Endothelium and Involves an Increased Superoxide Formation in DOCA-Salt Hypertension"
- 8. Jankowski V., Tölle M., Vanholder R., Schönfelder G., van der Giet M., Henning L., Schlüter H., Paul M., Zidek W.Jankowski J., Nature Med., 11, 223 - 227 (2005), "Uridine Adenosine Tetraphosphate: A Novel Endothelium-derived Vasoconstrictive Factor"
