The alkyne-containing 8-Bu(3-yne)T-Ado is an analogue of adenosine and a suitable molecular tool for the copper-catalysed Huisgen azide-alkyne [3+2] cycloaddition (CuAAC), which has attracted particular interest for the introduction of reporter groups and for the labelling of various biomolecules like binding proteins of adenosine by the so-called click-chemistry technique. References for CuAAC click chemistry: Presolski et al., Curr. Protoc. Chem. Biol., 3, 153 - 162 (2011); Hong et al., Angew. Chem. Int. Ed. Engl., 48, 9879 - 9883 (2009)