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β- Nicotinamide- 8- (3- butynylthio)adenine dinucleotide ( 8-Bu(3-yne)T-NAD⁺ ), sodium salt

Clickable analogue of β-NAD⁺
Cat. No.: N 055
CAS No.: [2022926-15-2]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: N 055-01
Unit: 1 µmol / ~0.7 mg

For other salt forms or higher purity please inquire. The alkyne-containing 8-Bu(3-yne)T-NAD+ is an analogue of NAD+ and a suitable molecular tool for the copper-catalysed Huisgen azide-alkyne [3+2] cycloaddition (CuAAC), which has attracted particular interest for the introduction of reporter groups and for the labelling of NAD+-binding proteins like substrate proteins of poly(ADP-ribose) polymerases (PARPs) by the so-called click-chemistry technique. References: Gibson et al., Science, 353, 45 - 50 (2016); Rogge et al., Methods Mol. Biol., 1813, 371 - 387 (2018).

Cat. No. N 055
CAS number [2022926-15-2]
Purity > 95% HPLC
Salt form Sodium
Storage temperature -70°C / -94°F
Molecular formula C₂₅H₃₁N₇O₁₄P₂S (free acid)
Molecular weight [g/mol] 747.6 (free acid)
Absorption max [nm] 276
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 21400