For other salt forms or analogues please inquire. 2'-cADPR is a regioisomer of the canonical second messenger cADPR (Cat. No. C 005) and of 3'-cADPR (Cat. No. C 404). Biosynthesis of 2'-cADPR was identified in Toll/interleukin-1 receptor (TIR)-domain containing proteins in plants and bacteria, and it is hypothesized to have a role in immune signaling. References: Wan et al., Science, 365, 799 - 803 (2019); Bayless et al., Sci. Adv., 9, eade8487 (2019); Hulin et al., Proc. Natl. Acad. Sci. U. S. A., 120, 7e2217114120 (2023).
An introduction into glycocyclic cADPR isomers written by Allen Lu and Philip Kranzusch - Harvard Medical School, Dana-Farber Cancer Institute - can be found here.
| Cat. No. | C 406 |
| CAS number | [pending] |
| Purity | > 98% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₅H₂₁N₅O₁₃P₂ (free acid) |
| Molecular weight [g/mol] | 541.3 (free acid) |
| Absorption max [nm] | 259 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 15000 |
| UV pH value | 7 |
| Solvent for UV data | Water |
