Guanosine analogue of interest as inhibitor of guanylate cyclase and in antiviral research. Detailed technical information available. References: Suzuki et al., Biochem. Biophys. Res. Commun., 156, 1144 - 1151 (1988); Johnson, Mol. Pharmacol., 35, 681 - 688 (1989); Walters et al., J. Pharm. Biomed. Anal., 19, 955 - 965 (1999). This compound is also part of the Ko-Libri compound library (K 001)
> 98% HPLC
-20°C / -4°F
Molecular weight [g/mol]
Absorption max [nm]
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]
1. Parra J., Cantabrana B.Hidalgo A., Life Sci., 66, 2563 - 2569 (2000), "Mechanism of Mifepristone-Induced Spasmolytic Effect on Isolated Rat Uterus"
2. Walters D. L., Jacobs D. L., Tomaszewski J. E.Graves S., J. Pharm. Biomed. Anal., 19, 955 - 965 (1999), "Analysis of Various Nucleosides in Plasma Using Solid Phase Extraction and High-Performance Liquid Chromatography with UV Detection"
3. Johnson R. A., Yeung S.-M. H., Stuebner D., Bushfield M.Shoshani I., Mol. Pharmacol., 35, 681 - 688 (1989), "Cation and Structural Requirements for P Site-Mediated Inhibition of Adenylate Cyclase"
4. Suzuki S., Lee B., Luo W., Tovell D., Robins M. J.Tyrrell D. L. J., Biochem. Biophys. Res. Commun., 156, 1144 - 1151 (1988), "Inhibition of Duck Hepatitis B Virus Replication by Purine 2',3'-Dideoxynucleosides"