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8-Br-TNP-GTP

8- Bromo- 2', 3'- O- (2, 4, 6- trinitrophenyl)guanosine- 5'- O- triphosphate ( 8-Br-TNP-GTP )
Fluorescent GTP analogue
Cat. No.: B 153
    
CAS No.: [pending]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: B 153-01
Unit: 1 µmol / ~0.8 mg
$138.00

For other salt forms please inquire. Fluorescent analogue of GTP with λexc 408 nm and λem 552 nm, which can substitute for GTP in the interaction with various enzymes and proteins. It is sensitive to indicators of local environment such as polarity and viscosity, and frequently exhibits a spectral shift and fluorescence enhancement upon binding to a protein. Potential inhibitor of various adenylyl isoforms and soluble guanylyl cyclase (sGC). References for the related TNP-GTP: Hiratsuka, T., J. Biol. Chem., 260, 4784 - 4790 (1985); Suryanarayana et al., J. Pharmacol. Exp. Ther., 330, 687 - 695 (2009).

 

Vial containing 100 µl of 10 mM aqueous solution of pH 8.

Cat. No. B 153
CAS number [pending]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution
Storage temperature -70°C / -94°F
Light-sensitive Yes
Molecular formula C₁₆H₁₆BrN₈O₂₀P₃ (for free acid)
Molecular weight [g/mol] 813.2 (for free acid)
Excitation max [nm] 408
Emission max [nm] 552
Absorption max [nm] 408
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 26500
UV pH value 8
Solvent for UV data 0.1 M Tris-HCl