For other salt forms or metabolites please inquire. Potent membrane-permeant activator of both isozymes I α and I β of cGMP-dependent protein kinase while only a poor stimulator of type II. Common agonists such as 8-Br-cGMP (Cat. No. B 004) or 8-pCPT-cGMP (Cat. No. C 009) mainly activate kinase subtypes I α and II. 8-Br-PET-cGMP is one of the best activators of isozyme I β and one of the best cyclic nucleotide muscle relaxants. Detailed technical information and updated reference list available. Reference: Sekhar et al., Mol. Pharmacol., 42, 103 - 108 (1992).
Cat. No. | P 003 |
CAS number | [144510-04-3] |
Purity | > 98% HPLC |
Salt form | Sodium |
Storage temperature | -20°C / -4°F |
Molecular formula | C₁₈H₁₄BrN₅O₇P · Na |
Molecular weight [g/mol] | 546.2 |
Modifications | 8-cGMP |
Target | PKG (cGK) Activator |
Lipophilicity | 2.83 |
Absorption max [nm] | 256 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 40000 |