Specially purified, typical fluorescent impurities removed. For other salt forms or metabolites of 8-Br-cGMP please inquire. Activator of cGMP-dependent protein kinases I α, I β & type II and cGMP-gated ion channels (cyclic GMP agonist). Increased metabolic stability compared to cGMP, but not completely stable as often stated.
8-pCPT-cGMP (Cat. No. C 009), a highly membrane-permeant and metabolically resistant cGMP-agonist seems to be superior for most applications. Detailed technical information and reference list available. Reference: Rapoport et al.,
Proc. Natl. Acad. Sci. USA,
79, 6470 - 6474 (1982).