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Alternative structural projections:


8- Bromoguanosine- 3', 5'- cyclic monophosphate ( 8-Br-cGMP ), sodium salt
PKG Agonist
Cat. No.: B 004
CAS No.: [51116-01-9]
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Product Name Price (net) Qty
Cat. No.: B 004-50
Unit: 50 µmol / ~22 mg
Specially purified, typical fluorescent impurities removed. For other salt forms or metabolites of 8-Br-cGMP please inquire. Activator of cGMP-dependent protein kinases I α, I β & type II and cGMP-gated ion channels (cyclic GMP agonist). Increased metabolic stability compared to cGMP, but not completely stable as often stated. 8-pCPT-cGMP (Cat. No. C 009), a highly membrane-permeant and metabolically resistant cGMP-agonist seems to be superior for most applications. Detailed technical information and reference list available. Reference: Rapoport et al., Proc. Natl. Acad. Sci. USA, 79, 6470 - 6474 (1982).
Cat. No. B 004
CAS number [51116-01-9]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₀BrN₅O₇P · Na
Molecular weight [g/mol] 446,1
Modifications 8-cGMP
Target PKG (cGK) Activator
Lipophilicity 1.17
Absorption max [nm] 260
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 16200