For other salt forms please inquire. 4-MB-cCMP is an analogue of the putative second messenger nucleotide cCMP (Cat. No. C 001) and main cellular metabolite of DB-cCMP (Cat. No. D 075), generated by unspecific esterases attacking the 2'-O-butyryl group of DB-cCMP. 4-MB-cCMP was found to be a low-potency partial activator of PKG Iα both in vitro and in vivo. It was also reported to display full and moderate activation of PKA RIα and PKA RIIα in vitro, while showing no evidence for PKA activation in vivo. Detailed technical information available. Reference: Wolter et al., Naunyn Schmiedebergs Arch. Pharmacol., 387, 1163 - 1175 (2014).
|Cat. No.||M 075|
|Purity||> 97% HPLC|
|Storage temperature||-20°C / -4°F|
|Molecular formula||C₁₃H₁₇N₃O₈P · Na|
|Molecular weight [g/mol]||397.3|
|Absorption max [nm]||248|
|Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]||16400|