For other salt forms or analogues please inquire. 2'-cADPR is a regioisomer of the canonical second messenger cADPR (Cat. No. C 005) and of 3'-cADPR (Cat. No. C 404). Biosynthesis of 2'-cADPR was identified in Toll/interleukin-1 receptor (TIR)-domain containing proteins in plants and bacteria, and it is hypothesized to have a role in immune signaling. References: Wan et al., Science, 365, 799 - 803 (2019); Bayless et al., Sci. Adv., 9, eade8487 (2019); Hulin et al., Proc. Natl. Acad. Sci. U. S. A., 120, 7e2217114120 (2023).
An introduction into glycocyclic cADPR isomers written by Allen Lu and Philip Kranzusch - Harvard Medical School, Dana-Farber Cancer Institute - can be found here.
|Cat. No.||C 406|
|Purity||> 98% HPLC|
|Storage temperature||-20°C / -4°F|
|Molecular formula||C₁₅H₂₁N₅O₁₃P₂ (free acid)|
|Molecular weight [g/mol]||541.3 (free acid)|
|Absorption max [nm]||259|
|Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]||15000|
|UV pH value||7|
|Solvent for UV data||Water|