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2',2''-Di-F-c-didGMP

2'- , 2''- Dideoxy- 2'-, 2''- difluoro- cyclic diguanosine monophosphate ( 2',2''-Di-F-c-didGMP ), sodium salt
Analogue of the bacterial second messenger c-diGMP
Cat. No.: D 210
    
CAS No.: [1334145-18-4]
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Product Name Price (net) Qty
Cat. No.: D 210-001
Unit: 0.1 µmol / ~69 µg
$150.00

For other salt forms please inquire. Analogue of the bacterial second messenger and STING activator c-diGMP (Cat. No. C 057) in which the ribose 2'-hydroxy groups have been replaced by fluorine atoms. 2',2''-Di-F-c-didGMP may be useful in studies on ligand-receptor interactions. Detailed technical information available. References: Burdette et al., Nature, 478, 515 - 518 (2011); Zhou et al., Bioorg. Med. Chem., 21, 4396 - 4404 (2013); Shanahan et al., Biochemistry, 52, 365 - 377 (2013); Launer-Felty et al., Nucleic Acids Res., 46, 2765 - 2776 (2018).

Cat. No. D 210
CAS number [1334145-18-4]
Purity >95% HPLC
Salt form Sodium
Appearance Solid
Storage temperature -20°C / -4°F
Molecular formula C₂₀H₂₂F₂N₁₀O₁₂P₂ (free acid)
Molecular weight [g/mol] 694.4 (free acid)
Absorption max [nm] 253
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 24300
UV pH value 7
Solvent for UV data Water