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Alternative structural projections:

2-Aza-ε-cAMP

2- Aza- 1, N⁶- ethenoadenosine- 3', 5'- cyclic monophosphate, sodium salt ( 2-Aza-ε-cAMP )
Fluorescent cAMP analogue
Cat. No.: A 015
    
CAS No.: [50663-90-6]
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Product Name Price (net) Qty
Cat. No.: A 015-05
Unit: 5 µmol / ~1.9 mg
$132.00
For other salt forms please inquire. Fluorescent cAMP analogue (λexc 358 nm, λem 494 nm). Detailed technical information available. References: Tsou et al., Anal. Biochem., 60, 163 - 169 (1974); Kraemer et al., J. Mol. Biol., 306, 1167 - 1177 (2001).
Cat. No. A 015
CAS number [50663-90-6]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Light-sensitive True
Molecular formula C₁₁H₁₀N₆O₆P · Na
Molecular weight [g/mol] 376,2
Modifications 1-cAMP, 2-cAMP
Target PKA (cAK) Activator
Excitation max [nm] 358
Emission max [nm] 494
Lipophilicity 1.42
Absorption max [nm] 290
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 5000
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  • 2. Kraemer A., Rehmann H., Cool R. H., Theiss C., de Rooij J., Bos H.Wittinghofer A., J. Mol. Biol., 306, 1167 - 1177 (2001), "Dynamic Interaction of cAMP with the Rap Guanine-nucleotide Exchange Factor Epac1"
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  • 6. Oegreid D., Doeskeland S. O.Miller J. P., J. Biol. Chem., 258, 1041 - 1049 (1983), "Evidence That Cyclic Nucleotides Activating Rabbit Muscle Protein Kinase I Interact with Both Types of cAMP Binding Sites Associated with the Enzyme"
  • 7. Leonard N. J., CRC Crit. Reviews Biochem., 15, 125 - 199 (1983), "Etheno-substituted Nucleotides and Coenzymes: Fluorescence and Biological Activity"
  • 8. Tsou K. C., Lo K. W.Yip K. F., FEBS Lett., 45, 47 - 49 (1974), "A Fluorescent Method for the Demonstration of Cyclic 3', 5'-AMP Phosphodiesterase Activity in Polyacrylamide Gel"
  • 9. Tsou K. C., Yip K. F.Lo K. W., Anal. Biochem., 60, 163 - 169 (1974), "1,N6-Etheno-2-aza-adenosine 3' , 5'-Monophosphate: A New Flurescent Substrate for Cycle Nucleotide Phosphodiesterase"