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Alternative structural projections:

2'-AHC-cGMP-Agarose

2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel ( 2'-AHC-cGMP-Agarose )
Cyclic GMP immobilized on agarose gel
Cat. No.: A 059
    
CAS No.: [pending]
Shipping: ambient
Product Name Price (net) Qty
Cat. No.: A 059-06
Unit: 0.6 ml
$111.00
Cat. No.: A 059-25
Unit: 2.5 ml
$347.00
Cat. No.: A 059-60
Unit: 6 ml
$700.00

The protein kinase G activator cyclic GMP immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2'-position of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'-ribose hydroxyl group, such as some phosphodiesterases.  This type of gel is offered as PDE-resistant version (Sp-2'-AHC-cGMPS-Agarose, Cat. No. A 052) as well. Detailed technical information available. References: Kim & Park, J. Niochem. Mol. Biol., 36, 299-304 (2003); Scholten et al., J. Proteome Res., 5, 1435 - 1447 (2006).
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.

Cat. No. A 059
CAS number [pending]
Storage temperature 4°C / 39°F
Modifications 2'-cGMP
  • 1. Kim E.Park J. M., J. Biochem. Mol. Biol., 36, 299 - 304 (2003), "Identification of Novel Target Proteins of Cyclic GMP Signaling Pathways Using Chemical Proteomics"