Basket (0 Items) - Amount: 0.00$2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, immobilized on agarose gel ( Sp-2'-AHC-cGMPS-Agarose )
PDE-resistant Sp-cGMPS immobilized to agarose
Cat. No.: A 052
The PDE-resistant PKG activator Sp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer attached to the ribose 2'- position of the ligand. The gel can be used for affinity chromatography of various cyclic nucleotide-responsive proteins, especially those which tolerate modification of the 2'- ribose hydroxyl group such as some phosphodiesterases. Compare: Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992). This type of gel is also available with normal cGMP (2'-AHC-cGMP-Agarose, Cat. No. A 059). Detailed technical information available.
Normally all affinity gels are supplied in pre-packed columns. The free beads without a column are available upon request.
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