0 Items - $0.00
A to Z


Uridine- 5'- O- (3- thiotriphosphate) ( UTP-γ-S ), sodium salt
Stable analogue of UTP
Cat. No.: U 010
CAS No.: [79049-97-1]
Shipping: Dry ice
Product Name Price (net) Qty
Cat. No.: U 010-05
Unit: 5 µmol / ~2.5 mg

For other salt forms or a guaranteed higher purity please inquire.
UTP-γ-S is a potent agonist of the P2Y2 and P2Y4 receptors with increased metabolic stability. It is also useful for modification with SH-reactive reporters or for connection to structures with SH-groups via a disulfide bond. Detailed technical information available. References: Lazarowski et al., Br. J. Pharmacol., 117, 203 - 209 (1996); Malmsjö et al., Eur. J. Pharmacol., 458, 305 - 311 (2003).


Vial containing 500 µl of 10 mM aqueous solution of pH 9

Cat. No. U 010
CAS number [79049-97-1]
Purity > 95% HPLC
Salt form Sodium
Appearance 10 mM aqueous solution of pH 9
Storage temperature -70°C / -94°F
Molecular formula C₉H₁₅N₂O₁₄P₃S (free acid)
Molecular weight [g/mol] 500.2 (free acid)
Absorption max [nm] 262
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 10000
  • 1. Wang J. L., Guo J.-X., Zhang Q.-Y., Wu J. J.-Q., Seifert R.Lushington G. H., Bioorg. Med. Chem., 15, 2993 - 3002 (2007), "A Conformational Transition in the Adenylyl Cyclase Catalytic Site Yields Different Binding Modes for Ribosyl-modified and Unmodified Nucleotide Inhibitors"
  • 2. Wihlborg A.-K., Balogh J., Wang L., Borna C., Dou Y., Joshi B. V., Lazarowski E. R., Jacobson K. A., Arner A.Erlinge D., Circ. Res., 98, 970 - 976 (2006), "Positive Inotropic Effects by Uridine Triphosphate (UTP) and Uridine Diphosphate (UDP) via P2Y2 and P2Y6 Receptors on Cardiomyocytes and Release of UTP in Man During Myocardial Infarction"
  • 3. Malmsjö M., Hou M., Pendergast W., Erlinge D.Edvinsson L., Eur. J. Pharmacol., 458, 305 - 311 (2003), "The Stable Pyrimidines UDPbetaS and UTPgammaS Discriminate Between Contractile Cerebrovascular P2 Receptors"
  • 4. Malmsjö M., Hou M., Harden T. K., Ortonne J. P., Pantev E., Edvinsson L.Erlinge D., J. Pharmacol. Exp. Ther., 293, 755 - 760 (2000), "Characterization of Contractile P2 Receptors in Human Coronary Arteries by Use of the Stable Pyrimidines Uridine 5'-O-Thiodiphosphate and Uridine 5'-O-3-Thiotriphosphate"
  • 5. Lazarowski E. R., Watt W. C., Stutts M. J., Brown H. A., Boucher R. C.Harden T. K., Brit. J. Pharmacol., 117, 203 - 209 (1996), "Enzymatic Synthesis of UTP-gamma -S, a Potent Hydrolysis Resistant Agonist of P(2U)-Purinoreceptors"