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Alternative structural projections:


8- Bromo- 2'- O- monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-Br-2'-O-MB-cAMPS ), sodium salt
Metabolically activatable form of the PKA inhibitor Rp-8-Br-cAMPS
Cat. No.: B 010
CAS No.: [788807-32-9]
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Product Name Price (net) Qty
Cat. No.: B 010-05
Unit: 5 µmol / ~2.6 mg
For other salt forms please inquire. Lipophilic precursor of the protein kinase A inhibitor Rp-8-Br-cAMPS (Cat. No. B 001). During metabolic activation by esterases the inhibitor and butyrate are released. Caution: Butyrate was shown to have distinct biological effects! Significantly more lipophilic and membrane-permeant compared to Rp-8-Br-cAMPS. Detailed technical information and updated reference list available for Rp-8-Br-cAMPS on request. Reference: Ruiz-Velasco et al., Circ. Res., 82, 557 - 565 (1998).
Cat. No. B 010
CAS number [788807-32-9]
Purity > 97% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₄H₁₆BrN₅O₆PS · Na
Molecular weight [g/mol] 516,2
cAMP modified at the exocyclic oxygen equatorial (Rp-)
Modifications 8-cAMP, 2'-cAMP
Lipophilicity 2.53
Absorption max [nm] 264
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000