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Alternative structural projections:


2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-2'-AHC-cGMPS )
The PKG inhibitor Rp-cGMPS functionalized for conjugation with markers and dyes or for immobilization
Cat. No.: A 123
CAS No.: [pending]
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Cat. No.: A 123-05
Unit: 5 µmol / ~2.5 mg

PDE-stable cyclic GMP analogue suitable for immobilization as affinity ligand (e.g. for purification of phosphodiesterases) or for coupling of various labelling structures including fluorophores. Detailed technical information available. This structure is also offered as a ligand immobilized to agarose (Rp-2'-AHC-cGMPS-Agarose, Cat. No. A 051), and without sulfur modification (2'-AHC-cGMP, Cat. No. A 048) Compare: Corrie et al., Prot. Expr. Purif., 3, 417 - 420 (1992).

Cat. No. A 123
CAS number [pending]
Purity > 98% HPLC
Salt form Free acid
Storage temperature -20°C / -4°F
Molecular formula C₁₇H₂₆N₇O₇PS
Molecular weight [g/mol] 503.5
Modifications 2'-cGMP
Absorption max [nm] 252
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 14300
  • 1. Corrie J. E. T., Pizza C., Makwana J.King R. W., Prot. Express. Purif., 3, 417 - 420 (1992), "Preparation and Properties of an Affinity Support for Purification of Cyclic AMP Receptor Protein from Escherichia coli"