For other salt forms or a guaranteed higher purity please inquire. 3'-O-Bn-GTP is an analogue of GTP where the ribose 3'-hydroxy group has been modified by an ether bond to a benzyl group. Significantly improved stability against esterases compared to other 2'/3'-esters of the ribose like MANT-GTP (Cat. M 032). Potential inhibitor of various adenylyl cyclase isoforms and soluble guanylyl cyclase (sGC). References for related GTP analogs and nucleoside triphosphate analogs: Dove et al., Mol. Pharmacol., 85, 598 - 607 (2014), Pinto et al., Biochem. Phamacol., 82, 358 - 370 (2011), Geduhn et al., J. Pharmacol. Exp. Ther., 336, 104 - 115 (2011), Gille et al., J. Biol. Chem., 279, 19955 - 19969 (2004)
Vial containing 100 µl of 10 mM aqueous solution of pH 7.6.
Cat. No. | B 193 |
CAS number | [1610778-75-0] |
Purity | > 95% HPLC |
Salt form | Sodium |
Appearance | 10 mM aqueous solution of pH 7.6 |
Storage temperature | -70°C / -94°F |
Molecular formula | C₁₇H₂₂N₅O₁₄P₃ (free acid) |
Molecular weight [g/mol] | 613.3 (free acid) |
Absorption max [nm] | 252 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 13500 |
UV pH value | 7 |
Solvent for UV data | Water |