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pA-2'-p

Adenosine- 2', 5'- O- bisphosphate ( pA-2'-p / 2'-pAp ), sodium salt

Cat. No.: A 449
    
CAS No.: [154146-84-6] (x Na+) / [108347-94-0] (2 Na+)
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Product Name Price (net) Qty
Cat. No.: A 449-10
Unit: 10 µmol / ~4.3 mg
$123.00

For other salt forms please inquire. In pA-2'-p phosphate groups are attached to both the ribose 2' position and the ribose 5' position of adenosine. It is an inhibitor of P2Y1 (Boyer et al. 1996) and exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors (Toth-Zsamboki et al. 2001). pA-2'-p inhibits ADP-induced platelet shape change and aggregation but it does not affect ADP-induced inhibition of adenylyl cyclase (Hechler et al. 1998). References: Boyer et al., Mol. Pharmacol., 50, 1323 -1329 (1996); Hechler et al., Blood92, 152 - 159 (1998); Toth-Zsamboki et al., Thromb. Haemost.86, 1338 - 1339 (2001).

Cat. No. A 449
CAS number [154146-84-6] (x Na+) / [108347-94-0] (2 Na+)
Purity > 95% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₅N₅O₁₀P₂ (free acid)
Molecular weight [g/mol] 427.2 (free acid)
Absorption max [nm] 259
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 15000
UV pH value 7
Solvent for UV data Water