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  1. Modifications: 1-cGMP
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cGMP modified at the exocyclic oxygen
  1. axial (Sp-) (2)
Lipophilicity

Lipophilicity ranking is based on log kw data. To be membrane-permeant, analogues should have a log kw of at least 1.2
See also: Lipophilic Ranking of Cyclic Nucleotide Analogs

  1. 3.00 - 4.00 (2)
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  1. PKG (cGK) Activator (3)

PDE- resistant PKG Activators

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  1. Cat. No.: F 013, CAS No.: [pending]

    8-Fluo-AHT-PET-cGMP

    8- (6- [Fluoresceinyl]aminohexylthio)- ß- phenyl- 1, N²- ethenoguanosine- 3', 5'- cyclic monophosphate ( 8-Fluo-AHT-PET-cGMP )
    SEE DETAILS
  2. Cat. No.: P 008, CAS No.: [172806-21-2]

    Sp-8-Br-PET-cGMPS

    8- Bromo- β- phenyl- 1, N²- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-Br-PET-cGMPS ), sodium salt
    SEE DETAILS
  3. Cat. No.: C 047, CAS No.: [1262749-63-2]

    Sp-8-pCPT-PET-cGMPS

    8- (4- Chlorophenylthio)- ß- phenyl- 1, N²- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-pCPT-PET-cGMPS ), sodium salt
    SEE DETAILS

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