For other salt forms please inquire. Sp-2'-O-MB-cAMPS is a lipophilic precursor of
Sp-cAMPS (Cat. No. A 003), a PDE-resistant activator of protein kinase A. During metabolic activation by esterases Sp-cAMPS and butyrate are released. Caution: Butyrate was shown to have distinct biological effects! Significantly more lipophilic and membrane-permeant compared to Sp-cAMPS. Detailed technical information available. Reference: Hügl et al.,
J. Biol. Chem.,
273, 17771 - 17779 (1998); Ouyang et al., Proc. Natl. Acad. Sci. USA, 105, 11993 - 11997 (2008).