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  1. Modifications: 8-cGMP
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cGMP modified at the exocyclic oxygen
  1. axial (Sp-) (6)
  2. equatorial (Rp-) (6)
Lipophilicity

Lipophilicity ranking is based on log kw data. To be membrane-permeant, analogues should have a log kw of at least 1.2
See also: Lipophilic Ranking of Cyclic Nucleotide Analogs

  1. 0.00 - 1.00 (1)
  2. 1.00 - 2.00 (7)
  3. 2.00 - 3.00 (10)
  4. 3.00 - 4.00 (4)
Target
  1. PKA (cAK) Activator (1)
  2. PKG (cGK) Activator (32)
  3. PKG (cGK) Inhibitor (5)

cGMP Analogues

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  1. Cat. No.: A 019, CAS No.: [pending]

    8-AET-cGMP-Agarose

    8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel ( 8-AET-cGMP-Agarose )
    SEE DETAILS
  2. Cat. No.: A 010, CAS No.: [pending]

    Sp-8-AET-cGMPS-Agarose

    8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer; immobilized on agarose gel ( Sp-8-AET-cGMPS-Agarose )
    SEE DETAILS
  3. Cat. No.: A 009, CAS No.: [pending]

    Rp-8-AET-cGMPS-Agarose

    8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer; immobilized on agarose gel ( Rp-8-AET-cGMPS-Agarose )
    SEE DETAILS

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