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  1. Modifications: 8-cGMP
  2. Target: PKG (cGK) Activator
cGMP modified at the exocyclic oxygen
  1. axial (Sp-) (5)
Lipophilicity

Lipophilicity ranking is based on log kw data. To be membrane-permeant, analogues should have a log kw of at least 1.2
See also: Lipophilic Ranking of Cyclic Nucleotide Analogs

  1. 0.00 - 1.00 (1)
  2. 1.00 - 2.00 (4)
  3. 2.00 - 3.00 (6)
  4. 3.00 - 4.00 (3)

cGMP Analogues

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  1. Cat. No.: A 029, CAS No.: [115974-70-4]

    8-AET-cGMP

    8- (2- Aminoethylthio)guanosine- 3', 5'- monophosphate
  2. Cat. No.: A 032, CAS No.: [144509-87-5]

    8-APT-cGMP

    8- (2- Aminophenylthio)guanosine- 3', 5'- monophosphate ( 8-APT-cGMP ), sodium salt
  3. Cat. No.: A 102, CAS No.: [pending]

    4-N₃-PET-8-Br-cGMP

    β- (4- Azidophenyl)- 1, N²- etheno- 8- bromoguanosine- 3', 5'- cyclic monophosphate ( 4-N₃-PET-8-Br-cGMP ), sodium salt
  4. Cat. No.: A 167, CAS No.: [144510-13-4]

    8-AHT-cGMP

    8- (6- Aminohexylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-AHT-cGMP )
  5. Cat. No.: A 186, CAS No.: [pending]

    4-N₃-PET-8-Biotin-11-cGMP

    β- (4- Azidophenyl)- 1, N²- etheno- 8- (2- (6- [biotinyl]aminohexanoyl)aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 4-N₃-PET-8-Biotin-11-cGMP / 4-N₃-PET-8-[Biotin]-AET-cGMP ), sodium salt

  6. Cat. No.: A 198, CAS No.: [221904-92-3]

    Sp-8-AET-cGMPS

    8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-AET-cGMPS )
  7. Cat. No.: B 004, CAS No.: [51116-01-9]

    8-Br-cGMP

    8- Bromoguanosine- 3', 5'- cyclic monophosphate ( 8-Br-cGMP ), sodium salt
  8. Cat. No.: B 006, CAS No.: [153660-03-8]

    Sp-8-Br-cGMPS

    8- Bromoguanosine- 3', 5'- monophosphorothioate, Sp- isomer ( Sp-8-Br-cGMPS ), sodium salt
  9. Cat. No.: B 014, CAS No.: [272445-71-3]

    8-Br-cGMP-AM

    8- Bromoguanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( 8-Br-cGMP-AM )
  10. Cat. No.: B 019, CAS No.: [370091-68-2]

    BCMCM-caged 8-Br-cGMP

    [6, 7- Bis(carboxymethoxy)coumarin- 4- yl)methyl- 8- bromoguanosine- 3', 5'- cyclic monophosphate ( BCMCM-caged 8-Br-cGMP )
  11. Cat. No.: B 025, CAS No.: [pending]

    8-Biotin-11-cGMP

    8- (2- (6- [Biotinyl]aminohexanoyl)aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-Biotin-11-cGMP / 8-[Biotin]-AET-cGMP ), sodium salt

  12. Cat. No.: B 185, CAS No.: [2201859-36-9]

    8-Bu(3-yne)T-cGMP

    8- (3- Butynylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-Bu(3-yne)T-cGMP ), sodium salt

  13. Cat. No.: C 009, CAS No.: [51239-26-0]

    8-pCPT-cGMP

    8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-pCPT-cGMP ), sodium salt
  14. Cat. No.: C 014, CAS No.: [160385-87-5]

    Sp-8-pCPT-cGMPS

    8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-pCPT-cGMPS ), sodium salt
  15. Cat. No.: C 033, CAS No.: [272445-72-4]

    8-pCPT-cGMP-AM

    8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester ( 8-pCPT-cGMP-AM )
  16. Cat. No.: C 045, CAS No.: [pending]

    8-pCPT-PET-cGMP

    8- (4- Chlorophenylthio)- β- phenyl- 1, N²- ethenoguanosine- 3', 5'- cyclic monophosphate ( 8-pCPT-PET-cGMP ), sodium salt
  17. Cat. No.: C 047, CAS No.: [1262749-63-2]

    Sp-8-pCPT-PET-cGMPS

    8- (4- Chlorophenylthio)- ß- phenyl- 1, N²- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-pCPT-PET-cGMPS ), sodium salt
  18. Cat. No.: D 045, CAS No.: pending

    DMACM-caged 8-Br-cGMP

    (7- Dimethylaminocoumarin- 4- yl)methyl- 8- bromoguanosine- 3', 5'- monophosphate (DMACM-caged 8-Br-cGMP)
  19. Cat. No.: D 087, CAS No.: [pending]

    8-[DY-547]-AET-cGMP

    8- (2- [DY-547]- aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-[DY-547]-AET-cGMP ), sodium salt
  20. Cat. No.: D 090, CAS No.: [pending]

    8-[DY-647]-AET-cGMP

    8- (2- [DY-647]- aminoethylthio)guanosine- 3', 5'- cyclic monophosphate ( 8-[DY-647]-AET-cGMP ), sodium salt

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