For other salt forms or a guaranteed higher purity please inquire. Analogue of 2'-deoxyguanosine-5'-triphosphate with only moderate intrinsic fluorescence (λexc 349 nm, λem ~430 nm). The fluorophore is supposed to have a certain sensitivity for its environment and can change its spectral properties upon binding. Useful for research into dGTP-dependent receptor proteins. Potential inhibitor of various adenylyl cyclase isoforms and soluble guanylyl cyclase (sGC). References for GTP analogues and nucleoside triphosphate analogues: Dove et al., Mol. Pharmacol., 85, 598 - 607 (2014), Pinto et al., Biochem. Phamacol., 82, 358 - 370 (2011), Geduhn et al., J. Pharmacol. Exp. Ther., 336, 104 - 115 (2011), Gille et al., J. Biol. Chem., 279, 19955 - 19969 (2004)
Vial containing 100 µl of 10 mM aqueous solution of pH 7.6.
Cat. No. | C 151 |
CAS number | [pending] |
Purity | > 95% HPLC |
Salt form | Sodium |
Appearance | 10 mM aqueous solution |
Storage temperature | -70°C / -94°F |
Light-sensitive | Yes |
Molecular formula | C₁₇H₂₀ClN₆O₁₄P₃ |
Molecular weight [g/mol] | 660.8 (for free acid) |
Excitation max [nm] | 349 |
Emission max [nm] | 430 |
Absorption max [nm] | 345 |
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 4000 |
UV pH value | 7 |
Solvent for UV data | Water |