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Alternative structural projections:

cGMP

Guanosine- 3', 5'- cyclic monophosphate ( cGMP ), sodium salt
Second messenger
Cat. No.: G 001
    
CAS No.: [40732-48-7]
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Product Name Price (net) Qty
Cat. No.: G 001-100
Unit: 100 µmol / ~37 mg
$36.00
For other salt forms or metabolites please inquire. Target receptors for the second messenger cyclic GMP include protein kinase G isozymes, cGMP-gated ion channels as well as cGMP-responsive phosphodiesterases. cGMP is metabolized rapidly by phosphodiesterases. Detailed technical information available.
Cat. No. G 001
CAS number [40732-48-7]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₁N₅O₇P · Na
Molecular weight [g/mol] 367,2
Lipophilicity 0.77
Absorption max [nm] 252
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 13500
  • 1. Pino S., Sponer J. E., Costanzo G., Saladino R.Di Mauro E., Life, 5, 372 - 384 (2015), "From Formamide to RNA, the Path is Tenuous but Continuous"
  • 2. Stadlbaur P., Sponer J., Costanzo G., Di Mauro E., Pino S.Sponer J. E., Chem. Eur. J., 21, 3596 - 3604 (2015), "Tetra-Loop-like Geometries Could Form the Basis of the Catalytic Activity of the Most Ancient Ribooligonucleotides"
  • 3. Sponer J. E., Sponer J., Giorgi A., Di Mauro E., Pino S.Costanzo G., J.Phys.Chem.B., 119, 2979 - 2989 (2015), "Untemplated Nonenzymatic Polymerization of 3',5'cGMP: A Plausible Route to 3',5'-Linked Ologonucleotides in Primordia"
  • 4. Bähre H., Hartwig C., Munder A., Wolter S., Stelzer T., Schirmer B., Beckert U., Frank D. W., Tümmler B., Kaever V.Seifert R., Biochem. Biophys. Res. Commun., 460, 909 - 914 (2015), "cCMP and cUMP Occur in Vivo"
  • 5. Wolter S., Dove S., Golombek M., Schwede F.Seifert R., Naunyn-Schmiedeberg's Arch. Pharmacol., 387, 1163 - 1175 (2014), "N4-monobutyryl-cCMP Activates PKA RIalpha and PKA RIIalpha more Potently and with Higher Efficacy than PKG Ialpha in Vitro but not in Vivo"
  • 6. Morasch M., Mast C. B., Langer J. K., Schilcher P.Braun D., Chem. Bio. Chem., 15, 879 - 883 (2014), "Dry Polymerization of 3', 5'-cyclic GMP to Long Strands of RNA"
  • 7. Beste K. Y., Spangler C. M., Burhenne H., Koch K.-W., Shen Y., Tang W.-J., Kaever V.Seifert R., PLoS ONE, 8, 0 - 0 (2013), "Nucleotidyl Cyclase Activity of Particulate Guanylyl Cyclase A: Comparison with Particulate Guanylyl Cyclases E and F, Soluble Guanylyl Cyclase and Bacterial Adenylyl Cyclases Cyaa and Edema Factor"
  • 8. Beckert U., Aw W. Y., Burhenne H., Fösterling L., Kaever V., Timmons L.Seifert R., PLoS ONE, 8, 0 - 0 (2013), "The Receptor-Bound Guanylyl Cyclase DAF-11 is the Mediator of Hydrogen Peroxide-Induced cGMP Increase in Caenorhabditis Elegans"
  • 9. Oeckl P.Ferger B., J. Neurosci. Methods, 203, 338 - 343 (2012), "Simultaneous LC-MS/MS Analysis of the Biomarkers cAMP and cGMP in Plasma, CSF and Brain Tissue"
  • 10. Gambaryan S., Butt E., Kobsar A., Geiger J., Rukoyatkina N., Parnova R., Nikolaev V. O.Walter U., Br. J. Pharmacol., 167, 1476 - 5381 (2012), "The Oligopeptide DT-2 is a Specific PKG I Inhibitor only In Vitro, not in Living Cells"
  • 11. Zong X., Krause S., Chen C.-C., Krüger J., Gruner C., Cao-Ehlker X., Fenske S., Wahl-Schott C.Biel M., J. Biol. Chem., 287, 26506 - 26512 (2012), "Regulation of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel Activity by cCMP"
  • 12. Gomelsky M., Mol. Microbiol., 79, 562 - 565 (2011), "cAMP, c-di-GMP, c-di-AMP and now cGMP: Bacteria use Them All!"
  • 13. Marden J. N., Dong Q., Roychowdhury S., Berleman J. E.Bauer C. E., Mol. Microbiol., 79, 600 - 615 (2011), "Cyclic GMP Controls Rhodospirillum Centenum Cyst Development"
  • 14. Osborne B. W., Wu J., McFarland C., Nickl C. K., Sankaran B., Casteel D. E., Woods V. L., Kornev A. P., Taylor S. S.Dostmann W. R. G., Structure, 19, 1317 - 1327 (2011), "Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication"
  • 15. Reinecke D., Burhenne H., Sandner P., Kaever V.Seifert R., FEBS Lett., 585, 3259 - 3262 (2011), "Human Cyclic Nucleotide Phosphodiesterases Possess a Much Broader Substrate-Specificity than Previously Appreciated"
  • 16. Werner K., Schwede F., Genieser H.-G., Geiger J.Butt E., Naunyn Schmiedebergs Arch. Pharmacol., 384, 169 - 176 (2011), "Quantification of cAMP and cGMP Analogs in Intact Cells: Pitfalls in Enzyme Immunoassays for Cyclic Nucleotides"
  • 17. Jäger R., Schwede F., Genieser H.-G., Koesling D.Russwurm M., Br. J. Pharmacol., 161, 1645 - 1660 (2010), "Activation of PDE2 and PDE5 cy Specific GAF Ligands: Delayed Activation of PDE5"
  • 18. Desch M., Schinner E., Kees F., Hofmann F., Seifert R.Schlossmann J., FEBS Lett., 584, 3979 - 3984 (2010), "Cyclic Cytidine 3',5'-Monophosphate (cCMP) Signals via cGMP Kinase I"
  • 19. Göttle M., Dove S., Kees F., Schlossmann J., Geduhn J., König B., Shen Y., Tang W.-J., Kaever V.Seifert R., Biochemistry, 49, 5494 - 5503 (2010), "Cytidylyl and Uridylyl Cyclase Activity of Bacillus anthracis Edema Factor and Bordetella pertussis CyaA"
  • 20. Bertinetti D., Schweinsberg S., Hanke S. E., Schwede F., Bertinetti O., Drewianka S., Genieser H.-G.Herberg F. W., BMC Chem Biol, 9, 0 - 0 (2009), "Chemical tools selectively target components of the PKA system"
  • 21. Sager G.Ravna A. W., Mini Rev. Med. Chem., 9, 1009 - 1013 (2009), "Cellular Efflux of cAMP and cGMP - a Question about Selectivity"
  • 22. Matthiesen K.Nielsen J., Biochem. J., 423, 401 - 409 (2009), "Binding of Cyclic Nucleotides to Phosphodiesterase 10A and 11A GAF Domains Does Not Stimulate Catalytic Activity"
  • 23. Schweinsberg S., Moll D., Burghardt N. C., Hahnefeld C., Schwede F., Zimmermann B., Drewianka S., Werner L., Kleinjung F., Genieser H.-G., Schuchhardt J.Herberg F. W., Proteomics, 8, 1212 - 1220 (2008), "Systematic interpretation of cyclic nucleotide binding studies using KinetXBase"
  • 24. Poppe H., Rybalkin S. D., Rehmann H., Hinds T. R., Tang X.-B., Christensen A. E., Schwede F., Genieser H.-G., Bos J. L., Doeskeland S. O., Beavo J. A.Butt E., Nature Methods, 5, 277 - 278 (2008), "Cyclic Nucleotide Analogs as Probes of Signaling Pathways"
  • 25. Herget S., Lohse M. J.Nikolaev V. O., Cell Signal., 20, 1423 - 1431 (2008), "Real-time Monitoring of Phosphodiesterase Inhibition in Intact Cells"
  • 26. Wang H., Liu Y., Hou J., Zheng M., Robinson H.Ke H., PNAS, 104, 5782 - 5787 (2007), "Structural Insight into Substrate Specifity of Phosphodiesterase 10"
  • 27. Moll D., Prinz A., Gesellchen F., Drewianka S., Zimmermann B.Herberg F. W., J. Neural. Transm., 113, 1015 - 1032 (2006), "Biomolecular Interaction Analysis in Functional Proteomics"
  • 28. Prieto D., Rivera L., Recio P., Rubio J. L. R., Hernandez M.Garcia-Sacristan A., J. Urol., 175, 1164 - 1170 (2006), "Role of Nitric Oxide in the Relaxation Elicited by Sildenafil in Penile Resistance Arteries"
  • 29. Song X. J., Wang Z. B., Gan Q.Walters E. T., J. Neurophysiol., 95, 479 - 492 (2006), "cAMP and cGMP Contribute to Sensory Neuron Hyperexcitability and Hyperalgesia in Rats with Dorsal Root Ganglia Compression"
  • 30. Kang G., Chepurny O. G., Malester B., Rindler M. J., Rehmann H., Bos J. L., Schwede F., Coetzee W. A.Holz G. G., J. Physiol.-London, 573, 595 - 609 (2006), "cAMP Sensor Epac as a Determinant of ATP-sensitive Potassium Channel Activity in Human Pancreatic Beta Cells and Rat INS-1 Cells"
  • 31. Cytrynska M., Zdybicka-Barabas A.Jakubowicz T., J. Insect Physiol., 52, 744 - 753 (2006), "Studies on the Role of Protein Kinase A in Humoral Immune Response of Galleria Mellonella Larvae"
  • 32. Badhwar A., Weston A. D., Murray J. B.Mercier A. J., Peptides, 27, 1281 - 1290 (2006), "A Role for Cyclic Nucleotide Monophosphates in Synaptic Modulation by a Crayfish Neuropeptide"
  • 33. Mewe M., Bauer C. K., Müller D.Middendorff R., Endocrinology, 147, 2051 - 2062 (2006), "Regulation of Spontaneous Contractile Activity in the Bovine Epididymal Duct by Cyclic Guanosine 5'- monophosphate-dependent Pathways"
  • 34. Diaz C. A., Alloco J., Powles M. A., Yeung L., Donald R. G. K., Anderson J. W.Liberator P. A., Mol. Biochem. Parasitol., 146, 78 - 88 (2006), "Characterization of Plasmodium falciparum cGMP-Dependent Protein Kinase(PfPKG): Antiparasitic Activity of a PKG Inhibitor"
  • 35. Lohmann S. M.Walter U., Frontiers Biosci., 10, 1313 - 1328 (2005), "Tracking Functions of cGMP-dependent Protein Kinase"
  • 36. Karaolis D. K. R., Cheng K., Lipsky M., Elnabawi A., Catalano J., Hyodo M., Hayakawa Y.Raufmann J.-P., Biochem. Biophys. Res. Commun., 329, 40 - 45 (2005), "3',5'-Cyclic Diguanylic Acid (c-di-GMP) Inhibits Basal and Growth Factor-stimulated Human Colon Cancer Cell Proliferation"
  • 37. Karaolis D. K. R., Rashid M. H., Chythanya R., Luo W., Hyodo M.Hayakawa Y., Antimicrob. Agents Chemother., 49, 1029 - 1038 (2005), "c-di-GMP (3'-5'-Cyclic Diguanylic Acid) Inhibits Staphylococcus Aureus Cell-Cell Interactions and Biofilm Formation"
  • 38. Genieser H.-G., Bos J. L., Christensen A. E., Doeskeland S. O., Havemann U., Manzau U., Rehmann H.Schwede F., Poster #THP016 Montreal, 12, 0 - 0 (2004), "Analogues of Cyclic AMP to Distinguish Between PKA and Epac"
  • 39. Gambaryan S., Geiger J., Schwarz U. R., Butt E., Begonja A., Obergfell A.Walter U., Blood, 103, 2593 - 2600 (2004), "Potent Inhibition of Human Platelets by cGMP Analogs Independent of cGMP-dependent Protein Kinase"
  • 40. Sager G., Neurochem. Int., 45, 865 - 873 (2004), "Cyclic GMP Transporters"
  • 41. Rehmann H., Schwede F., Doeskeland S. O., Wittinghofer A.Bos J. L., J. Biol. Chem., 278, 38548 - 38556 (2003), "Ligand-mediated Activation of the cAMP-responsive Guanine Nucleotide Exchange Factor Epac"
  • 42. Christensen A. E., Selheim F., de Rooij J., Dremier S., Schwede F., Dao K. K., Martinez A., Maenhaut C., Bos J. L., Genieser H.-G.Doeskeland S. O., J. Biol. Chem., 278, 35394 - 35402 (2003), "cAMP Analog Mapping of Epac1 and cAMP-Kinase. Discriminating Analogs Demonstrate that Epac and cAMP-Kinase Act Synergistically to Promote PC-12 Cell Neurite Extension"
  • 43. Punta M., Cavalli A., Torre V.Carloni P., Proteins., 52, 332 - 338 (2003), "Molecular Modeling Studies on CNG Channel from Bovine Retinal Rod: A Structural Model of the Cyclic Nucleotide-Binding Domain"
  • 44. Christensen A. E.Doeskeland S. O., Handbook of Cell Signaling Academic Press/Elsevier Science San Diego CA, 2, 549 - 554 (2003), "Cyclic Nucleotide Analogs as Tools to Investigate Cyclic Nucleotide Signaling"
  • 45. Wall M. E., Francis S. H., Corbin J. D., Grimes K., Ritchie-Jannetta R., Kotera J., MacDonald B. A., Gibson R. R.Trewhella J., Proc. Natl. Acad. Sci. U.S.A., 100, 2380 - 2385 (2003), "Mechanism Associated with cGMP Binding and Activation of cGMP-Dependent Protein Kinase"
  • 46. Deng W., Parbhu-Patel A., Meyer D. J.Baker D. A., Biochem. J., 374, 559 - 565 (2003), "The Role of Two Novel Regulatory Sites in the Activation of the cGMP-dependent Protein Kinase from Plasmodium Falciparum"
  • 47. McKenzie R. C., Oda Y., Szepietowski J. C., Behne M. J.Mauro T., Acta Derm.-Venerol., 83, 414 - 418 (2003), "Defective Cyclic Guanosine Monophosphate-gated Calcium Channels and the Pathogenesis of Psoriasis"
  • 48. Zagotta W. N., Olivier N. B., Black K. D., Young E. C., Olson R.Gouaux E., Nature, 425, 200 - 205 (2003), "Structural Basis for Modulation and Agonist Specifity of HCN Pacemaker Channels"
  • 49. Christensen A. E., de Rooij J., Kopperud R. K., Nilsen O. K., Dao K. K., Schwede F., Bos J. L., Genieser H.-G.Doeskeland S. O., Abstract of the 13th Protein Kinase Symposium, 0, 5 - 5 (2002), "Comparison of the cAMP Binding Sites of EPAC-1 and cAMP-Kinase"
  • 50. Salowe S. P., Wiltsie J., Liberator P. A.Donald R. G. K., Biochemistry, 41, 4385 - 4391 (2002), "The Role of a Parasite-Specific Allosteric Site in the Distinctive Activation Behavior of Eimeria tenella cGMP-Dependent Protein Kinase"
  • 51. Nies A. T., Spring H., Thon W. F., Keppler D.Jedlitschky G., J. Urol., 167, 2271 - 2275 (2002), "Immunolocalization of Multidrug Resistance Protein 5 in the Human Genitourinary System"
  • 52. Martinez S. E., Wu A. Y., Glavas N. A., Tang X.-B., Turley S., Hol W. G. J.Baevo J. A., Proc. Natl. Acad. Sci. U.S.A., 99, 13260 - 13265 (2002), "The Two GAF Domains in Phosphodiesterase 2A Have Distinct Roles in Dimerization and in cGMP Binding"
  • 53. Deng W.Baker D. A., Mol. Microbiol., 44, 1141 - 1151 (2002), "A Novel Cyclic GMP-dependent Protein Kinase is Expressed in the Ring Stage of the Plasmodium Falciparum Life Cycle"
  • 54. Sundkvist E., Jaeger R.Sager G., Biochem. Pharmacol., 63, 945 - 949 (2002), "Pharmacological Characterization of the ATP-dependent Low K(m) Guanosine 3', 5'-Cyclic Monophosphate (cGMP) Transporter in Human Erythrocytes"
  • 55. Won H.-S., Lee T.-W., Park S.-H.Lee B.-J., J. Biochem., 277, 11450 - 11455 (2002), "Stoichiometry and Structural Effect of the Cyclic Nucleotide Binding to Cyclic AMP Receptor Protein"
  • 56. Lin S.-H., Kovac L., Chin A. J., Chin C. C. Q.Lee J. C., Biochemistry, 41, 2946 - 2955 (2002), "Ability of E. Coli Cyclic AMP Receptor Protein To Differentiate Cyclic Nucleotides: Effects of Single Site Mutations"
  • 57. Sellak H., Yang X., Cao X., Cornwell T., Soff G. A.Lincoln T., Circ. Res., 90, 405 - 412 (2002), "Sp1 Trancription Factor as a Molecular Target for Nitric Oxide- and Cyclic Nucleotide-Mediated Suppression of cGMP-dependent Protein Kinase-1@ Expression in Vascular Smooth Muscle Cells"
  • 58. He Y. J.Karpen J. W., Biochemistry, 40, 286 - 295 (2001), "Probing the Interactions between cAMP and cGMP in Cyclic Nuleotide-Gated Channels Using Covalently Tethered Ligands"
  • 59. Forte L. R., Eber S. L., London R. M., Miedema B. W.Kim H. D., 11th Intl. Conference on Second Messengers and Phosphoproteins Melbourne Australia, 0, 0 - 0 (2001), "Uroguanylin, Cyclic GMP and Colocancer"
  • 60. Roelofs J., Snippe H., Kleineidam R. G.Van Haastert P. J. M., Biochem. J., 354, 697 - 706 (2001), "Guanylate Cyclase in Dictyostelium Discoideum with the Topology of Mammalian Adenylate Cyclase"
  • 61. Boadu E., Vaskinn S., Sundkvist E., Jaeger R.Sager G., Biochem. Pharmacol., 62, 425 - 429 (2001), "Inhibition by Guanosine Cyclic Monophosphate (cGMP) Analogues of Uptake of [H-3]3', 5'-cGMP without Stimulation of ATPase Activity in Human Erythrocyte Inside-out Vesicles"
  • 62. Takuma K., Lee E., Enomoto R., Mori K., Baba A.Matsuda T., Br. J. Pharmacol., 133, 841 - 848 (2001), "Ibudilast Attenuates Astrocyte Apoptosis via Cyclic GMP Signalling Pathway in an In Vitro Reperfusion Model"
  • 63. Frame M., Wan K. F., Tate R., Vandenabeele P.Pyne N. J., Cell. Signal., 13, 735 - 741 (2001), "The Gamma Subunit of the Rod Photoreceptor cGMP Phosphodiesterase Can Modulate the Proteolysis of two cGMP Binding cGMP-specific Phosphodiesterases (PDE6 and PDE5) by Caspase-3"
  • 64. Becker A. J., Uckert S., Stief C. G.Jonas U., Urol. Res., 29, 366 - 370 (2001), "Plasma Levels of Cyclic Guanosine-3', 5'-monophosphate in the Cavernous and Systemic Blood of Healthy Males During Different Functional Conditions of the Penis"
  • 65. Sabetkar M., Naseem K. M., Tullett J. M., Friebe A., Koesling D.Bruckdorfer K. R., Nitric Oxide: Biol. Chem., 5, 233 - 242 (2001), "Synergism Between Nitric Oxide and Hydrogen Peroxide in the Inhibition of Platelet Function: The Roles of Soluble Guanylyl Cyclase and Vasodilator-Stimulated Phosphoprotein"
  • 66. Rich T. C., Tse T. E., Rohan J. G., Schaack J.Karpen J. W., J. Gen. Physiol., 118, 63 - 77 (2001), "In Vivo Assessment of Local Phosphodiesterase Activity Using Tailored Cyclic Nucleotide-gated Channels as cAMP Sensors"
  • 67. Saparov S. M., Kozono D., Rothe U., Agre P.Pohl P., J. Biol. Chem., 276, 31515 - 31520 (2001), "Water and Ion Permeation of Aquaporin-1 in Planar Lipid Bilayers"
  • 68. Bader B., Butt E., Palmetshofer A., Walter U., Jarchau T.Drueckes P., J. Biomol. Screen., 6, 255 - 264 (2001), "A cGMP-dependent Protein Kinase Assay for High Throughput Screening Based on Time-Resolved Fluorescence Resonance Energy Transfer"
  • 69. Zoraghi R., Kunz S., Gong K.Seebeck T., J. Biol. Chem., 276, 11559 - 11566 (2001), "Characterization of TbPDE2A, a Novel Cyclic Nucleotide-specific Phosphodiesterase from the Protozoan Parasite Trypanosoma Brucei"
  • 70. Shalaby T., Liniger M.Seebeck T., Eur. J. Biochem., 268, 6197 - 6206 (2001), "The Regulatory Subunit of a cGMP- regulated Protein Kinase A of Trypanosoma Brucei"
  • 71. Wätjen W., Benters J., Haase H., Schwede F., Jastorff B.Beyersmann D., Toxicol., 157, 167 - 175 (2001), "Zn2+ and Cd2+ Increase the cyclic GMP level in PC12 Cells by Inhibition of the cyclic Nucleotide Phosphodiesterase"
  • 72. Schwede F., Brustugun O. T., Zorn-Kruppa M., Doeskeland S. O.Jastorff B., Bioorg. Med. Chem. Lett., 10, 571 - 573 (2000), "Membrane-permeant, Bioactivatable Analogues of cGMP as Inducers of Cell Death in IPC-81 Leukemia Cells"
  • 73. Crane J. K., Shanks K. L.Majumdar S., Arch. Biochem. Biophys., 376, 163 - 170 (2000), "Redistribution of Cyclic GMP in Response to Sodium Butyrate in Colon Cells"
  • 74. White R. E., Kryman J. P., El-Mowafy A. M., Han G. C.Carrier G. O., Circ. Res., 86, 897 - 905 (2000), "cAMP-Dependent Vasodilators Cross-Activate the cGMP-Dependent Protein Kinase to Stimulate BKCa Channel Activity in Coronary Artery Smooth Muscle Cells"
  • 75. Corbin J. D., Turko I. V., Beasley A.Francis S. H., Eur. J. Biochem., 267, 2760 - 2767 (2000), "Phosphorylation of Phosphodiesterase-5 by Cyclic Nucleotide-Dependent Protein Kinase Alters its Catalytic and Allosteric cGMP-Binding Activities"
  • 76. Conti M.Jin S.-L. C., Prog. Nucl. Acid Res. Mol. Biol., 63, 1 - 38 (2000), "The Molecular Biology of Cyclic Nucleotide Phosphodiesterases"
  • 77. Hagen V., Bendig J., Frings B., Wiesner B.Kaupp U. B., 12th Protein Kinase Symp. NO/cGMP and Protein Kinase Signaling Bad Brückenau/Germany, 0, 0 - 0 (2000), "Novel Coumarinylmethyl-Caged Cyclic Nucleotides: Photochemistry and Application to Cyclic Nucleotide-Gated Channels"
  • 78. Koizumi M.Breaker R. R., Biochemistry, 39, 8983 - 8992 (2000), "Molecular Recognition of cAMP by an RNA Aptamer"
  • 79. Enrich M. J. D., Villamarin J. A., Martinez J. I. R.Ibarguren I., Anal. Biochem., 285, 105 - 112 (2000), "Measurement of Adenosine 3',5'-Cyclic Monophosphate and Guanosine 3',5'-Cyclic Monophosphate in Mussel (Mytilus galloprovincialis Lmk.) by High-Performance Liquid Chromatography with Diode Array Detection"
  • 80. Ho Y.-S. J., Burden L. M.Hurley J. H., EMBO J., 19, 5288 - 5299 (2000), "Structure of the GAF Domain, a Ubiquitous Signaling Motif and a new Class of Cyclic GMP Receptor"
  • 81. Kobialka M.Gorczyca W. A., Acta Biochim. Polon., 47, 517 - 528 (2000), "Particulate Guanylyl Cyclases: Multiple Mechanisms of Activation"
  • 82. Muhonen W. W.Shabb J. B., Protein Sci., 9, 2446 - 2456 (2000), "Resonant Mirror Biosensor Analysis of Type I(Alpha) cAMP-dependent Protein Kinase B Domain-Cyclic Nucleotide Interactions"
  • 83. Sundkvist E., Jaeger R.Sager G., BBA, 1463, 121 - 130 (2000), "Leukotriene C-4 (LTC4) does not Share a Cellular Efflux Mechanism with cGMP: Characterisation of cGMP Transport by Inside-out Vesicles from Human Erythrocytes"
  • 84. Smith J. A., Reed R. B., Francis S. H., Grimes K.Corbin J. D., J. Biol. Chem., 275, 154 - 158 (2000), "Distinguishing the Roles of the Two Different cGMP-binding Sites for Modulating Phosphorylation of Exogenous Substrate (Heterophosphorylation) and Autophosphorylation of cGMP-dependent Protein Kinase"
  • 85. Taylor M. K.Uhler M. D., J. Biol. Chem., 275, 28053 - 28062 (2000), "The Amino-terminal Cyclic Nucleotide Binding Site of the Type II cGMP-dependent Protein Kinase is Essential for Full cyclic Nucleotide-dependent Activation"
  • 86. Ohyama T., Hackos D. H., Frings S., Hagen V., Kaupp U. B.Korenbrot J. I., J. Gen. Physiol., 116, 735 - 753 (2000), "Fraction of the Dark Current Carried by Ca2+ through cGMP-gated Ion Channels of Intact Rod and Cone Photoreceptors"
  • 87. Boadu E.Sager G., Biochim. Biophys. Acta, 1509, 467 - 474 (2000), "ATPase Activity and Transport by a cGMP Transporter in Human Erythrocyte Ghosts and Proteoliposome-reconstituted Membrane Extracts"
  • 88. Schwarz U. R., Kobsar A. L., Koksch M., Walter U.Eigenthaler M., Biochem. Pharmacol., 60, 1399 - 1407 (2000), "Inhibition of Agonist-Induced p42 and p38 Mitogen-activated Protein Kinase Phosphorylation and CD40 Ligand/P-Selectin Expression by Cyclic Nucleotide-Regulated Pathways in Human Platelets"
  • 89. Mou H., Grazio III H. J., Cook T. A., Beavo J. A.Cote R. H., J. Biol. Chem., 274, 18813 - 18820 (1999), "cGMP Binding to Noncatalytic Sites of Mammalian Rod Photoreceptor Phosphodiesterase is Regulated by Binding of Its Gamma and Delta Subunits"
  • 90. Wallis R. M., Corbin J. D., Francis S. H.Ellis P., Am. J. Cardiol., 83, 3 - 12 (1999), "Tissue Distribution of Phosphodiesterase Families and the Effects of Sildenafil on Tissue Cyclic Nucleotides, Platelet Function, and the Contractile Responses of Trabeculae Carneae and Aortic Rings in Vitro"
  • 91. Sunderman E. R.Zagotta W. N., J. Gen. Physiol., 113, 621 - 640 (1999), "Sequence of Events Underlying the Allosteric Transition of Rod Cyclic Nucleotide-Gated Channels"
  • 92. Sunderman E. R.Zagotta W. N., J. Gen. Physiol., 113, 601 - 619 (1999), "Mechanism of Allosteric Modulation of Rod Cyclic Nucleotide-Gated Channels"
  • 93. Seya K., Furukawa K. I.Motomura S., Anal. Biochem., 272, 243 - 249 (1999), "A Fluorometric Assay for Cyclic Guanosine 3', 5'-Monophosphate Incorporating a Sep-Pak Cartridge and Enzymatic Cycling"
  • 94. Nikolakaki E., Fissentzidis A., Giannakouros T.Georgatsos J. G., Mol. Cell. Biochem., 197, 117 - 128 (1999), "Purification and Characterization of a Dimer Form of the cAMP-dependent Protiein Kinase from Mouse Liver Cytosol"
  • 95. Rosenzweig S., Yan W., Dasso M.Spielman A. I., J. Neurophysiol., 81, 1661 - 1665 (1999), "Possible Novel Mechanism for Bitter Taste Mediated through cGMP"
  • 96. Biel M., Ludwig A., Zong X.Hofmann F., Rev. Physiol. Biochem. Pharmacol., 136, 165 - 181 (1999), "Hyperpolarization-Activated Cation Channels: A Multi-Gene Family"
  • 97. Biel M., Zong X.Hofmann F., Adv. Second Messenger Phosphoprotein Res., 33, 231 - 250 (1999), "Cyclic Nucleotide Gated Channels"
  • 98. White R. E., Adv. Second Messenger Phosphoprotein Res., 33, 251 - 277 (1999), "Cyclic GMP and Ion Channel Regulation"
  • 99. Biel M., Zong X., Ludwig A., Sautter A.Hofmann F., Rev. Physiol. Biochem. Pharmacol., 135, 151 - 171 (1999), "Structure and Function of Cyclic Nucleotide-Gated Channels"
  • 100. Francis S. H.Corbin J. D., Crit. Rev. Clin. Lab. Sci., 36, 275 - 328 (1999), "Cyclic Nucleotide-Dependent Protein Kinases: Intracellular Receptors for cAMP and cGMP Action"
  • 101. Hirsch J. R., Weber G., Kleta I.Schlatter E., J. Physiol., 519, 645 - 655 (1999), "A Novel cGMP-regulated K+Channel in Immortalized Human Kidney Epithelial Cells (IHKE-1)"
  • 102. Hirsch J. R., Meyer M., Mägert H.-J., Forssmann W.-G., Mollerup S., Herter P., Weber G., Cermak R., Ankorina-Stark I., Schlatter E.Kruhoffer M., J. Am. Soc. Nephrol., 10, 472 - 480 (1999), "cGMP-dependent and -independent Inhibition of a K+ Conductance by Natriuretic Peptides: Molecular and Functional Studies in Human Proximal Tubule Cells"
  • 103. Suwastika I. N.Gehring C. A., Archives of Biochemistry and Biophysics, 367, 137 - 139 (1999), "The plasma membrane H+ ATPase from Tradescantia Stem and leaf tissue is modulated in vitro by cGMP"
  • 104. Schwede F., Genieser H.-G.Jastorff B., Cell. Mol. Biol. Lett., 4, 466 - 0 (1999), "Cyclic Nucleotide Analogs as Prospective Drugs"
  • 105. Wei J.-Y., Cohen E. D., Genieser H.-G.Barnstable C. J., J. Mol. Neurosci., 10, 53 - 64 (1998), "Substituted cGMP Analogs Can Act as Selective Agonists of the Rod Photoreceptor cGMP-Gated Cation Channel"
  • 106. Boadu E.Sager G., Naunyn-Schmied. Arch. Pharmacol. XIIIth. Int. Congr. Pharmacol. Munich R 413 P 3.19, 358, 2 - 0 (1998), "Characterization of the Transporter Responsible for Cellular cGMP Export"
  • 107. Smolenski A., Burkhardt A. M., Eigenthaler M., Butt E., Gambaryan S., Lohmann S. M.Walter U., Naunyn-Schmied. Arch. Pharmacol., 358, 134 - 139 (1998), "Functional Analysis of cGMP-dependent Protein Kinases I and II as Mediators of NO/cGMP Effects"
  • 108. Renaudon B., Bescond J., Bois P.Lenfant J., Recept. Channel., 5, 315 - 322 (1998), "Nucleotide Modulation Of F-Channel Activity In Rabbit Sino-Atrial Node Myocytes"
  • 109. Lee S.-J., Madden P. J.Shen S. S., Exp. Cell Res., 242, 328 - 340 (1998), "U73122 Blocked the cGMP-Induced Calcium Release in Sea Urchin Eggs"
  • 110. Riegel J. A., Maddrell S. H. P., Farndale F. W.Caldwell F. M., J. Exp. Biol., 201, 3411 - 3418 (1998), "Stimulation of Fluid Secretion of Malpighian Tubules of Drosophila Melanogaster Meig. by Cyclic Nucleotides of Inosine, Cytidine, Thymidine and Uridine"
  • 111. Han J., Kim E., Lee S. H., Yoo S., Ho W.-K.Earm Y. E., Pflugers Arch.-Eur. J. Physiol., 435, 388 - 393 (1998), "cGMP Facilitates Calcium Current via cGMP-Dependent Protein Kinase in Isolated Rabbit Ventricular Myocytes"
  • 112. Hebert M. C., Schwede F., Jastorff B.Cote R. H., J. Biol. Chem., 273, 5557 - 5565 (1998), "Structural Features of the Noncatalytic cGMP Binding Sites of Frog Photoreceptor Phoshodiesterase Using cGMP Analogs"
  • 113. Schultz C., Vaskinn S., Kildalsen H.Sager G., Biochemistry, 37, 1161 - 1166 (1998), "Cyclic AMP Stimulates the Cyclic GMP Egression Pump in Human Erythrocytes - Effects of Probenecid, Verapamil, Progesterone, Theophylline, IBMX, Forskolin, and Cyclic AMP on Cyclic GMP Uptake and Association to Inside-out Vesicles"
  • 114. Vaandrager A. B., Edixhoven M., Bot A. G. M., Kroos M. A., Jarchau T., Lohmann S. M., Genieser H.-G.De Jonge H. R., J. Biol. Chem., 272, 11816 - 11823 (1997), "Endogenous Type II cGMP-Dependent Protein Kinase Exists as a Dimer in Membranes and can be Functionally Distinguished from the Type I Isoforms"
  • 115. Wegener J. W.Nawrath H., Eur. J. Pharmacol., 326, 37 - 44 (1997), "Cardiac Effects of Isoliquiritigenin"
  • 116. Bonkale W. L., Cowburn R. F., Winblad B.Fastbom J., Brain Res., 763, 1 - 13 (1997), "Autoradiographic Characterization of (H-3)cGMP Binding Sites in the Rat Brain."
  • 117. Krass J. D., Jastorff B.Genieser H.-G., Anal. Chem., 69, 2575 - 2581 (1997), "Determination of Lipophilicity by Gradient Elution High-Performance Liquid Chromatography"
  • 118. Chu D.-M., Corbin J. D., Grimes K. A.Francis S. H., J. Biol. Chem., 272, 31922 - 31928 (1997), "Activation by Cyclic GMP Binding Causes an Apparent Conformational Change in cGMP-Dependent Protein Kinase"
  • 119. Pietta P. G., Mauri P. L., Gardana C.Benazzi L., J. Chromatogr., 690, 343 - 347 (1997), "Assay of Soluble Guanylate Cyclase Activity by Isocratic High-performance Liquid Chromatography"
  • 120. Gamm D. M., Francis S. H., Angelotti T. P., Corbin J. D.Uhler M. D., J. Biol. Chem., 270, 27380 - 27388 (1996), "The Type II Isoform of cGMP-dependent Protein Kinase is Dimeric and Possesses Regulatory and Catalytic Properties Distinct from the Type I Isoforms"
  • 121. Wei J. Y., Cohen E. D., Yan Y.-Y., Genieser H.-G.Barnstable C. J., Biochemistry, 35, 16815 - 16823 (1996), "Identification of Competitive Antagonists of the Rod Photoreceptor cGMP-Gated Cation Channel: Beta-Phenyl-1,N(2)-Etheno-Substituted cGMP Analogues as Probes of the cGMP-Binding Site"
  • 122. Wei J. Y., Cohen E. D., Yan Y.-Y., Genieser H.-G.Barnstable C. J., American Society for Neuroscience, 0, 880 - 0 (1996), "PET-substituted cGMP Analogs: Novel Antagonists of Rod Photoreceptor cGMP-gated Channel"
  • 123. Butt E.Walter U., in 'Platelets: A Practical Approach' IRL Press Oxford, 0, 259 - 278 (1996), "Cyclic Nucleotides: Measurement and Function"
  • 124. Reed R. B., Sandberg M., Jahnsen T., Lohmann S. M., Francis S. H.Corbin J. D., J. Biol. Chem., 271, 17570 - 17575 (1996), "Fast and Slow Cyclic Nucleotide-Dissociation Sites in cAMP-Dependent Protein Kinase are Transposed in Type I(Beta) cGMP-Dependent Protein Kinase"
  • 125. Finn J. T., Grunwald M. E.Yau K. W., Annu. Rev. Physiol., 58, 395 - 426 (1996), "Cyclic Nucleotide-Gated Ion Channels: An Extended Family With Diverse Functions"
  • 126. Appleton I., Tomlinson A.Willoughby D. A., In Adv. Pharmacol. (Ed.: August J.T. Anders M.W. Murad F. Coyle J.T.) Academic Press San Diego, 35, 27 - 78 (1996), "Induction of Cyclo-Oxygenase and Nitric Oxide Synthase in Inflammation"
  • 127. Newton R. P., in Proceedings of the Phytochemical Society of Europe (R.P.Newton/T.J.Walton Clarendon Press Oxford, 0, 158 - 181 (1996), "11. Mass Spectrometric Analysis of Cyclic Nucleotides and Related Enzymes"
  • 128. Hampl V., Huang J. M. C., Weir E. K.Archer S. L., Physiol. Res., 44, 39 - 44 (1995), "Activation of the cGMP-Dependent Protein Kinase Mimics the Stimulatory Effect of Nitric Oxide and cGMP on Calcium-Gated Potassium Channels"
  • 129. Butt E., Beltman J., Becker D. E., Jensen G. S., Rybalkin S. D., Jastorff B.Baevo J. A., Mol. Pharmacol., 47, 340 - 347 (1995), "Characterization of Cyclic Nucleotide Phosphodiesterases with Cyclic AMP Analogs: Topology of the Catalytic Site and Comparison with Other Cyclic AMP-Binding Proteins"
  • 130. Muresan S., Bologa C., Mracec M., Chiriac A., Jastorff B., Simon Z.Naray-Szabo G., J. Mol. Struct., 342, 161 - 171 (1995), "Comparative QSAR Study with Electronic and Steric Parameters for cAMP Derivatives with Large Substituents in Positions 2, 6 and 8"
  • 131. Li W. W., Luan S., Schreiber S. L.Assmann S. M., Plant Physiol., 106, 957 - 961 (1994), "Cyclic AMP Stimulates K+ Channel Activity in Mesophyll Cells of Vicia faba L."
  • 132. Muresan S., Bologa C., Chiriac A., Jastorff B., Kurunczi L.Simon Z., Quant. Struct.-Act. Relat., 13, 242 - 248 (1994), "Comparative Structure-Affinity Relations by MTD for Binding of Cycloadenosine Monophosphate Derivatives to Protein Kinase Receptors"
  • 133. Defagot C.Zubin P., Biol. Res., 27, 193 - 197 (1994), "Preparation, Production and Functional Characterization of Anti cAMP and cGMP Antibodies"
  • 134. Biel M., Zong X., Distler M., Bosse E., Klugbauer N., Murakami M., Flockerzi V.Hofmann F., Proc. Natl. Acad. Sci. USA, 91, 3505 - 3509 (1994), "Another Member of the Cyclic Nucleotide-Gated Channel Family, Expressed in Testis, Kidney, and Heart"
  • 135. Murad F., in Advances in Pharmacology J.T. August M.W. Anders F. Murad (eds.) Academic Press San Diego, 26, 87 - 115 (1994), "Cyclic GMP: Synthesis, Metabolism, and Function"
  • 136. Francis S. H.Corbin J. D., Adv. Pharmacol., 26, 115 - 170 (1994), "Progress in Understanding the Mechanism and Function of Cyclic GMP-Dependent Protein Kinase"
  • 137. Bowler C., Yamagata H., Neuhaus G.Chua N.-H., Genes & Development, 8, 2188 - 2202 (1994), "Phytochrome signal transduction pathways are regulated by reciprocal control mechanisms"
  • 138. Pfeiffer S., Janistyn B., Jessner G., Pichorner H.Ebermann R., Phytochemistry, 36, 259 - 262 (1994), "Gaseous nitric oxide stimulates guanosine- 3', 5'-cyclic monophosphate (cGMP) formation in spruce needles"
  • 139. Tulshian D., Czarniecki M., Doll R. J.Ahn H.-S., J. Med. Chem., 36, 1210 - 1220 (1993), "Synthesis and Phosphodiesterase Activity of Carboxylic Acid Mimetics of Cyclic Guanosine 3', 5'- Monophosphate"
  • 140. Shakiba S., Assil K. K., Listhaus A. D., Munguia D., Flores-Aguilar M., Vuong C., Wiley C. A., Tolman R. L., Karkas J. D., Bergeron-Lynn G.Freeman W. R., Invest. Ophtalmol. Vis. Sci., 34, 2903 - 2910 (1993), "Evaluation of Retinal Toxicity and Liposome Encapsulation of the Anti-CMV Drug 2'-nor-cyclic GMP"
  • 141. Fischer E. H., Angew. Chem., 105, 1181 - 1188 (1993), "Protein-Phosphorylierung und Zellregulation II (Nobel-Vortrag)"
  • 142. Naß N., Colling C., Cramer M., Genieser H.-G., Butt E., Winkler E., Jaenicke L.Jastorff B., Biochem. J., 285, 129 - 136 (1992), "Mapping of the Epitope/Paratope Interactions of a Monoclonal Antibody Directed Against Adenosine- 3', 5'- monophosphate"
  • 143. Johnson R. L., Van Haastert P. J. M., Kimmel A. R., Saxe III C. L., Jastorff B.Devreotes P. N., J. Biol. Chem., 267, 4600 - 4607 (1992), "The Cyclic Nucleotide Specificity of Three cAMP Receptors in Dictyostelium"
  • 144. Butt E., Nolte C., Schulz S., Beltman J., Beavo J. A., Jastorff B.Walter U., Biochem. Pharmacol., 43, 2591 - 2600 (1992), "Analysis of the Functional Role of cGMP-dependent Protein Kinase in Intact Human Platelets Using a Specific Activator 8-pCPT-cGMP"
  • 145. Kumar V. D.Weber I. T., Biochemistry, 31, 4643 - 4649 (1992), "Molecular Model of the Cyclic GMP-Binding Domain of the Cyclic GMP-Gated Ion Channel"
  • 146. Van Ments-Cohen M., Genieser H.-G., Jastorff B., Van Haastert P. J. M.Schaap P., FEMS Microbiol. Lett., 82, 9 - 14 (1991), "Kinetics and Nucleotide Specificity of a Surface cAMP Binding Site in Dictyostelium discoideum, which is not Down-regulated by cAMP"
  • 147. Ruth P., Landgraf W., Keilbach A., May B., Egleme C.Hofmann F., Eur. J. Biochem., 202, 1339 - 1344 (1991), "The Activation of Expressed cGMP-dependent Protein Kinase Isozymes I alpha and I beta is Determined by the Different Amino-termini"
  • 148. Sandberg M., Butt E., Nolte C., Fischer L., Halbrügge M., Beltmann J., Jahnsen T., Genieser H.-G., Jastorff B.Walter U., Biochem. J., 279, 521 - 527 (1991), "Characterization of Sp- 5, 6- dichloro-1-ß-D-ribofuranosylbenzimidazole- 3',5'- monophosphorothioate (Sp-5,6-DCl-cBIMPS) as a Potent and Specific Activator of cyclic AMP- dependent Protein Kinase in Cell Extracts and Intact Cells"
  • 149. Worby A., Mensah L. M.Murray K. J., Biochem. Pharmacol., 42, 1318 - 1321 (1991), "Identification of the Novel Rat Liver IBMX-insensitive Phosphodiesterase as a Non-specific Phosphodiesterase Capable of Hydrolysing cCMP"
  • 150. Shabb J. B., Buzzeo B. D., Ng L.Corbin J. D., J. Biol. Chem., 266, 24320 - 24326 (1991), "Mutating Protein Kinase cAMP-binding Sites into cGMP-binding Sites"
  • 151. Wood P. L., Pharmacol. Rev., 43, 1 - 25 (1991), "Pharmacology of the Second Messenger, Cyclic Guanosine 3', 5'- Monophosphate, in the Cerebellum"
  • 152. Setzer W. N.Bentrude W. G., J. Org. Chem., 56, 7212 - 7218 (1991), "Solid-State Conformations of Nucleosid Cyclic 3',5'-Monophosphate Derivatives. Effects of Substituents on Phosphorus on Ring Geometries and n/sigma* Orbital Interactions"
  • 153. Van Lookeren Campagne M. M., Diaz F. V., Jastorff B., Winkler E., Genieser H.-G.Kessin R. W., J. Biol. Chem., 265, 5847 - 5854 (1990), "Characterization of the Yeast Low Km cAMP- Phosphodiesterase With cAMP Analogues"
  • 154. Manganiello V. C., Tanaka T.Murashima S., Cyclic Nucleotide Phosphodiesterases: Structure M.D. Houslay ed. - Wiley Interscience Chichester UK, 0, 61 - 82 (1990), "Cyclic GMP-Stimulated Cyclic Nucleotide Phosphodiesterases"
  • 155. Manganiello V. C., Smith C. J., Degerman E.Belfrage P., Cyclic Nucleotide Phosphodiesterases: Structure; M.D. Houslay ed. - Wiley Interscience Chichester UK, 0, 87 - 116 (1990), "Cyclic GMP-Inhibited Cyclic Nucelotide Phosphodiesterases"
  • 156. Newton R. P., Salih S. G.Khan J. A., Cyclic Nucleotide Phosphodiesterases: Structure M.D. Houslay ed., Wiley Interscience Chichester UK, 17, 141 - 159 (1990), "Cyclic CMP-Specific Phosphodiesterase Activity"
  • 157. Barsony J.Marx S. J., Proc. Natl. Acad. Sci., 87, 1188 - 1192 (1990), "Immunocytology on Microwave-fixed Cells Reveals Rapid and Agonist-specific Changes in Subcellular Accumulation Patterns or cAMP or cGMP"
  • 158. Wolfe L., Corbin J. D.Francis S. H., J. Biol. Chem., 264, 7734 - 7741 (1989), "Characterization of a Novel Isozyme of cGMP-dependent Protein Kinase From Bovine Aorta"
  • 159. Caretta A.Saibil H., J. Cell Biol., 108, 1517 - 1522 (1989), "Visualization of Cyclic Nucleotide Binding Sites in the Vertebrate Retina by Fluorescence Microscopy"
  • 160. Shanahan M. F.Edwards B. M., Endocrinology, 125, 1074 - 1081 (1989), "Stimulation of Glucose Transport in Rat Cardiac Myocytes by Guanosine-3',5'-Cyclic-Monophosphate"
  • 161. Francis S. H., Noblett B. D., Todd B. W., Wells J. N.Corbin J. D., Mol. Pharmacol., 34, 506 - 517 (1988), "Relaxation of Vascular and Tracheal Smooth Muscle by Cyclic Nucleotide Analogs That Preferentially Activate Purified cGMP-Dependent Protein Kinase"
  • 162. Gillespie P. G.Baevo J. A., J. Biol. Chem., 263, 8133 - 8141 (1988), "Characterization of a Bovine Cone Photoreceptor Phosphodiesterase Purified by Cyclic GMP-Sepharose Chromatography"
  • 163. Clair T., Ally S., Tagliaferri P., Robins R. K.Cho-Chung Y. S., FEBS Lett., 224, 377 - 384 (1987), "Site-selective Cyclic AMP Analogs Induce Nuclear Translocation of the RII cAMP Receptor Protein in Ha-MuSV-Transformed NIH/3T3 Cells"
  • 164. Johnson J. D., Walters J. D.Mills J. S., Anal. Biochem., 162, 291 - 295 (1987), "A Continous Fluorescence Assay for Cyclic Nucleotide Phosphodiesterase Hydrolysis of Cyclic GMP"
  • 165. Corbin J. D., Oegreid D., Miller J. P., Suva R. H., Jastorff B.Doeskeland S. O., J. Biol. Chem., 261, 1208 - 1214 (1986), "Studies of cGMP Analog Specificity and Function of the Two Intrasubunit Binding Sites of cGMP-dependent Protein Kinase"
  • 166. Erneux C., Miot F., Van Haastert P. J. M.Jastorff B., J. Cyclic Nucleotide Protein Phosphorylation Res., 10, 463 - 472 (1985), "The Binding of Cyclic Nucleotide Analogs to a Purified Cyclic GMP- Stimulated Phosphodiesterase from Bovine Adrenal Tissue"
  • 167. Braumann T.Jastorff B., J. Chromatogr., 350, 105 - 118 (1985), "Physicochemical Characterization of Cyclic Nucleotides by Reversed Phase High-Performance Liquid Chromatography. II. Quantitative Determination of Hydrophobicity"
  • 168. Kesbeke F., Baraniak J., Bulgakov R., Jastorff B., Morr M., Petridis G., Stec W. J., Seela F.Van Haastert P. J. M., Eur. J. Biochem., 151, 179 - 186 (1985), "Cyclic Nucleotide Specificity of the Activator and Catalytic Sites of a cGMP-stimulated cGMP Phosphodiesterase from Dictyostelium discoideum."
  • 169. Ebright R. H., Le Grice S. F. J., Miller J. P.Krakow J. S., J. Mol. Biol., 182, 91 - 107 (1985), "Analogs of Cyclic AMP that Elicit the Biochemically Defined Conformational Change in Catabolite Gene Activator Protein (CAP) but do not Stimulate Binding to DNA"
  • 170. Braumann T.Jastorff B., J. Chromatography, 329, 321 - 330 (1985), "Physico-chemical Characterization of Cyclic Nucleotides by Reversed-Phase High-Performance Liquid Chromatography. I. Cation Binding in the Mobile Phase"
  • 171. Beebe S. J., Holloway R., Rannels S. R.Corbin J. D., J. Biol. Chem., 259, 3539 - 3547 (1984), "Two Classes of cAMP Analogs Which Are Selective for the Two Different cAMP-binding Sites of Type II Protein Kinase Demonstrate Synergism When Added Together to Intact Adipocytes"
  • 172. Erneux C., Couchie D., Dumont J. E.Jastorff B., Adv. Cyclic Nucleotide Protein Phosphorylation Res., 16, 107 - 118 (1984), "Cyclic Nucleotide Derivatives as Probes of Phosphodiesterase Catalytic and Regulatory sites"
  • 173. Kingston E. E., Beynon J. H.Newton R., Biomedical Mass Spectrometry, 11, 367 - 374 (1984), "The Identification of Cyclic Nucleotides from Living Systems Using Collison-induced Dissociation of Ions Generated by Fast Atom Bombardment Mass Spectrometry"
  • 174. Van Haastert P. J. M.Kien E., J. Biol. Chem., 258, 9636 - 9642 (1983), "Binding of cAMP Derivatives to Dictyostelium Discoideum Cells. Activation Mechanism of the Cell Surface cAMP Receptor"
  • 175. Van Haastert P. J. M., J. Biol. Chem., 258, 9643 - 9648 (1983), "Binding of cAMP and Adenosine Derivatives to Dictyostelium Discoideum Cells. Relationship of Binding, Chemotactic and Antagonistic Activities"
  • 176. Couchie D., Petridis G., Jastorff B.Erneux C., Eur. J. Biochem., 136, 571 - 575 (1983), "Characterization of Phosphodiesterase Catalytic Sites by Means of Cyclic Nucleotide Derivatives"
  • 177. Gronenborn A. M.Clore G. M., Biochemistry, 21, 4040 - 4048 (1982), "Proton Nuclear Magnetic Resonance Studies on Cyclic Nucleotide Binding to the Escherichia coli Adenosine Cyclic 3',5'- Phosphate Receptor Protein"
  • 178. de Wit R. J. W., Arents J. C.Van Driel R., FEBS Lett., 145, 150 - 154 (1982), "Ligand Binding Properties of the Cytoplasmic cAMP-Binding Protein of Dictyostelium discoideum"
  • 179. de Wit R. J. W., Hoppe J., Stec W. J., Baraniak J.Jastorff B., Eur. J. Biochem., 122, 95 - 99 (1982), "Interaction of cAMP Derivatives with the 'Stable' cAMP-Binding Site in the cAMP-Dependent Protein Kinase Type I"
  • 180. Varughese K. I., Lu C. T.Kartha G., J. Am. Chem. Soc., 104, 3398 - 3401 (1982), "The Crystal and Molecular Structure of Cyclic Adenosine 3', 5'- Monophosphate Sodium Salt, Monoclinic Form"
  • 181. Donnelly T. E.Barron B., Biochim. Biophys. Acta, 657, 168 - 178 (1981), "Effects of Divalent Metals on the Specificity of Inhibitors of the Cyclic Nucleotide Phosphodiesterases from Bovine Heart"
  • 182. Miller J. P., Uno H., Christensen L. F., Robins R. K.Meyer R. B., Biochem. Pharmacol., 30, 509 - 515 (1981), "Effect of Modification of the 1-, 2-, and 6-Positions of 9-β-D-Ribofuranosylpurine Cyclic 3',5'- Phosphate on the Cyclic Nucleotide Specificity of Adenosine Cyclic 3',5'- Phosphate and Guanosine Cyclic 3',5'- Phosphate-dependent Protein Kinases"
  • 183. Erneux C., Couchie D., Dumont J. E., Baraniak J., Stec W. J., Garcia Abbad E., Petridis G.Jastorff B., Eur. J. Biochem., 115, 503 - 510 (1981), "Specificity of cyclic GMP Activation of a Multi-substrate Cyclic Nucleotide Phosphodiesterase from Rat Liver"
  • 184. Robberecht P., Deschodt-Lanckman M., Woussen-Colle M.-C., De Neef P., Camus J. C.Christophe J., Mol. Pharmacol., 17, 268 - 274 (1980), "Butyryl Derivatives of Cyclic GMP Interfere With the Biological and the Immunological Properties of the Pancreozymin-Gastrin Family of Peptides"
  • 185. Rannels S. R.Corbin J. D., J. Biol. Chem., 255, 7085 - 7088 (1980), "Two Different Intrachain cAMP Binding Sites of cAMP-Dependent Protein Kinases"
  • 186. Francis S. H., Lincoln T. M.Corbin J. D., J. Biol. Chem., 255, 620 - 626 (1980), "Characterization of a Novel cGMP Binding Protein from Rat Lung"
  • 187. Engels J., Bioorg. Chem., 8, 9 - 16 (1979), "Synthesis and Reactivity of Guanosine 3', 5'- Phosphoric Acid Alkyl Esters"
  • 188. Nishikori K.Maeno H., J. Biol. Chem., 254, 6099 - 6109 (1979), "Close Relationship between Adenosine 3',5'-Monophosphate-dependent Endogenous Phosphorylation of a Specific Protein and Stimulation of Calcium Uptake in Rat Uterine Microsomes"
  • 189. Cheng Y.-C.Bloch A., J. Biol. Chem., 253, 2522 - 2524 (1978), "Demonstration, in Leukemia L-1210 Cells, of a Phosphodiesterase Acting on 3':5'-Cyclic CMP but not on 3':5'-Cyclic AMP or 3':5'-Cyclic GMP"
  • 190. Kuo J. F., Brackett N. L., Shoji M.Tse J., J. Biol. Chem., 253, 2518 - 2521 (1978), "Cytidine 3':5'-Monophosphate Phosphodiesterase in Mammalian Tissues - Occurence and Biological Involvement"
  • 191. O'Neill J. P., Li A. P.Hsie A. W., BBA, 497, 35 - 45 (1977), "Action of Cyclic Nucleotide Analogues in Chinese Hamster Ovary Cells"
  • 192. Eilen E.Krakow J. S., Biochim. Biophys. Acta, 493, 115 - 121 (1977), "Effects of Cyclic Nucleotides on the Conformational States of the alpha Core of the Cyclic AMP Receptor Protein"
  • 193. Antonoff R. S., Ferguson J. J.Idelkope G., Biochem. Photobiol., 23, 327 - 329 (1976), "Direct Photo-Affinity Labeling of Cyclic Nucleotide Binding Proteins With Guanosine- 3',5'-Monophosphate"
  • 194. Miller J. P., Boswell K. H., Mian A. M., Meyer R. B., Robins R. K.Khwaja T. A., Biochemistry, 15, 217 - 223 (1976), "2'- Derivatives of Guanosine and Inosine Cyclic 3', 5'- Phosphates. Synthesis, Enzymic Activity, and the Effect of 8- Substituents"
  • 195. Sasaki Y., Suzuki N., Sowa T., Nozawa R.Yokota T., Biochemistry, 15, 1408 - 1413 (1976), "Effects of 8-Substituted Adenosine 3',5'-monophosphate Derivatives on High Km Phosphodiesterase Activity"
  • 196. Meyer R. B., Uno H., Shuman D. A., Robins R. K., Simon L. N.Miller J. P., J. Cyclic Nucl. Res., 1, 159 - 167 (1975), "The Synthesis of 2,6-Disubstituted-9-beta-D-Ribofuranosylpurine Cyclic 3',5'-Phosphates and the Selectivity of cAMP and cGMP-specific Enzymes to Substituents in These Positions"
  • 197. Garbers D. L., Suddath J. L.Hardman J. G., BBA, 377, 174 - 185 (1975), "Enzymatic Formation of Inosine 3', 5'-Monophosphate and of 2'-Deoxyguanosine 3', 5'-Monophosphate - Inosinate and Deoxyguanylate Cyclase Activity"
  • 198. Michal G., Mühlegger K., Nelboeck M., Thiessen C.Weimann G., Pharmacol. Res. Commun., 6, 203 - 252 (1974), "Cyclophosphates VI. Cyclophosphates as Substrates and Effectors of Phosphodiesterase"
  • 199. Antonoff R. S.Ferguson J. J., J. Biol. Chem., 249, 3319 - 3321 (1974), "Photoaffinity Labeling with Cyclic Nucleotides"
  • 200. Fikus M., Kwast-Welfeld J., Kazimierczuk Z.Shugar D., Acta Biochim. Polon., 21, 465 - 473 (1974), "Biochemical Studies on Some New Analogues of Adenosine- 3', 5'- Cyclic Phosphate, Including Isoguanosine- 3', 5'- Cyclic Phosphate"
  • 201. Kuo J. F., Miyamoto E.Reyes P. L., Biochem. Pharmacol., 23, 2011 - 2021 (1974), "Activation and Dissociation of Adenosine 3', 5'- Monophosphate-dependent and Guanosine 3', 5'- monophosphate-dependent Protein Kinases by Various Cyclic Nucleotide Analogs"
  • 202. Nelböck M., Michal G.Weimann G., Pure Appl. Chem., 35, 411 - 437 (1973), "Analogues of Cyclic AMP and their Physiological Response"
  • 203. Anderson W. B., Perlman R. L.Pastan I., J. Biol. Chem., 247, 2717 - 2722 (1972), "Effect of Adenosine 3', 5'- Monophosphate Analogues on the Activity of the Cyclic Adenosine 3', 5'- Monophosphate Receptor in Escherichia coli"
  • 204. Steiner A. L., Parker C. W.Kipnis D. M., J. Biol. Chem., 247, 1106 - 1113 (1972), "Radioimmunoassay for Cyclic Nucleotides. I. Preparation of Antibodies and Iodinated Cyclic Nucleotides"
  • 205. Du Plooy M., Michal G., Weimann G., Nelboeck M.Paoletti R., Biochim. Biophys. Acta, 230, 30 - 39 (1971), "Cyclophosphates I. Effect of Various Cyclophosphates on Phosphorylase b Kinase Activation"
  • 206. Blecher M., Ro'Ane J. T.Flynn P. D., Arch. Biochem. Biophys., 142, 351 - 362 (1971), "Biological Roles for 3',5'- Cyclic Nucleotides. I. Lipolytic Agents in isolated Rat Epididymal Adipose Cells and Substrates for Adipose Tissue Phosphodiesterase"
  • 207. Blecher M., Ro'Ane J. T.Flynn P. D., Biochem. Pharmacol., 20, 249 - 251 (1971), "Biochemical Activities of Tubercidin 3', 5'-cyclic Monophosphate in Rat Epididymal Adipose Tissue"
  • 208. Michal G., Nelböck M.Weimann G., Z. Anal. Chem., 252, 189 - 193 (1970), "Cyclophosphate III. Spaltung Verschiedener Cyclophosphate durch Phosphodiesterase aus Herz und Fettgewebe"
  • 209. Kuo J. F.Greengard P., Biochem. Biophys. Res. Commun., 40, 1032 - 1038 (1970), "Stimulation of Adenosine 3', 5'- Monophosphate- dependent and Guanosine 3', 5'- Monophosphate- dependent Protein Kinase by some Analogs of Adenosine 3', 5'- Monophosphate"
  • 210. Levine R. A.Washington A., Endocrinology, 87, 377 - 382 (1970), "Glycogenolytic Activity of Cyclic 3',5'-Monophosphates in Perfused Rat Liver"

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