For other salt forms or analogues please inquire. c[U(2',5')pA(3',5')p] is a hybrid purine-pyrimidine cyclic dinucleotide that was identified as a natural nucleotide second messenger in the oyster species Crassostrea gigas (C. gigas, Pacific oyster) and Crassostrea virginica (C. virginica, Eastern oyster). In C. virginica, c[U(2',5')pA(3',5')p] induced a gene expression pattern strongly associated with innate immunity, including upregulated expression of genes encoding transcription factors (NF-kB, IRFs, and STATs), immune receptors (NLRs, RLRs, cGLRs, and STING), and proteins with homology to human interleukins and inhibitor of apoptosis (IAP) factors. Reference: Li et al.,Cell (2023), https://doi.org/10.1016/j.cell.2023.05.038.
| Cat. No. | C 399 |
| CAS number | [pending] |
| Purity | > 95% HPLC |
| Salt form | Sodium |
| Storage temperature | -20°C / -4°F |
| Molecular formula | C₁₉H₂₃N₇O₁₄P₂ (free acid) |
| Molecular weight [g/mol] | 635.4 (free acid) |
| Absorption max [nm] | 260 |
| Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] | 22500 |
| UV pH value | 7 |
| Solvent for UV data | Water |
