Useful as starting structure for 2'-deoxyguanosine nucleotides modified in position 8, and of potential interest in research on bromine-stressed DNA. Detailed technical information available. References: Lin, J. Med. Chem., 28, 1194 - 1198 (1985); Shen et al., Biochemistry, 40, 2041 - 2051 (2001); Esposito et al., Org. Biomol. Chem., 2, 313 - 318 (2004). This compound is also part of the Ko-Libri compound library (K 001)
> 98% HPLC
-20°C / -4°F
Molecular weight [g/mol]
Absorption max [nm]
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]
1. Esposito V., Randazzo A., Piccialli G., Petraccone L., Giancola C.Mayol L., Org. Biomol. Chem., 2, 313 - 318 (2004), "Effects of an 8-Bromodeoxyguanosine Incorporation on The Parallel Quadruplex Structure [d(TGGGT)]4"
2. Shen Z., Mitra S. N., Wu W., Chen Y., Yang Y., Qin J.Hazen S. L., Biochemistry, 40, 2041 - 2051 (2001), "Eosinophil Peroxidase Catalyzes Bromination of Free Nucleosides and Double-Stranded DNA"
3. Lin T.-S., Cheng J.-C., Ishiguro K.Sartorelli A. C., J. Med. Chem., 28, 1194 - 1198 (1985), "8-Substituted Guanosine and 2´-Deoxyguanosine Derivates as Potential Inducers of the Differentiation of Friend Erythroleukemia"