8-Br-2',3'-cAMP is considered to be a membrane-permeable analogue of 2',3'-cAMP (Biolog Cat. No. A 307) (Kosmacz et al. 2018). 2',3'-cAMP is a positional isomer of the natural second messenger 3',5'-cAMP (Biolog Cat. No. A 001) and was found to be produced by organ systems such as rat and mouse kidney and mouse brain from RNA degradation. It was also recently reported to promote the formation of stress granules in Arabidopsis thaliana. Reference: Kosmacz et al., Plant Physiol., 177, 411 - 421 (2018).
|Cat. No.||B 280|
|Purity||> 97% HPLC|
|Storage temperature||-20°C / -4°F|
|Molecular formula||C₁₀H₁₀BrN₅O₆P · Na|
|Molecular weight [g/mol]||430.1|
|Absorption max [nm]||264|
|Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]||17000|