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Alternative structural projections:


N⁶- Benzoyladenosine- 3', 5'- cyclic monophosphate ( 6-Bnz-cAMP ), sodium salt
Membrane-permeant, site-selective PKA agonist
Cat. No.: B 009
CAS No.: [30275-80-0]
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Product Name Price (net) Qty
Cat. No.: B 009-10
Unit: 10 µmol / ~4.6 mg

For other salt forms or metabolites of 6-Bnz-cAMP please inquire. Site-selective and membrane-permeant activator of cAMP-dependent protein kinase (cAK) which does not activate Epac and thus can be used as an Epac-negative control. Increased metabolic stability against PDE compared to cAMP. Selects site A of both cAK isozymes and thus can be used for synergistic activation of type II when combined with site B II- selective analogues such as Sp-8-CPT-cAMPS (Cat. No. C 012) or 8-PIP-cAMP (Cat. No. P 002). For preferential stimulation of cAK type I a combination with the site B I-selective analogue 2-Cl-8-MA-cAMP (Cat. No. C 080) or 8-HA-cAMP (Cat. No. H 006) can be used. For more details on site selectivity please inquire. Detailed technical information and updated reference list available. References: Christensen et al., J. Biol. Chem., 278, 35394 - 35402 (2003); Bos, Trends Biochem. Sci., 31, 680 - 686 (2006).

Cat. No. B 009
CAS number [30275-80-0]
Purity > 98% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₇H₁₅N₅O₇P · Na
Molecular weight [g/mol] 455,3
Target PKA (cAK) Activator
Lipophilicity 1.90
Absorption max [nm] 279
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 19700