Biomarker for analysis of chlorine stressed RNA and useful starting structure for nucleosides and nucleotides modified in position 5 of the pyrimidine nucleobase. For 5- chlorocytosine please inquire. Detailed technical information available. Reference: Badouard et al., J. Chromatogr., 827, 26 - 31 (2005). This compound is also part of the Ko-Libri compound library (K 001)
> 98% HPLC
-20°C / -4°F
Molecular weight [g/mol]
Absorption max [nm]
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹]
1. Stanley N. R., Pattison D. I.Hawkins C. L., Chem. Res. Toxicol., 23, 1293 - 1302 (2010), "Ability of Hypochlorous Acid and N-Chloramines to Chlorinate DNA and Its Constituents"
2. Badouard C., Masuda M., Nishino H., Cadet J., Favier A.Ravanat J.-L., J. Chromatogr., 827, 26 - 31 (2005), "Detection of Chlorinated DNA and RNA Nucleosides by HPLC Coupled to Tandem Mass Spectrometry as Potential Biomarkers of Inflammation"
3. Masuda M., Suzuki T., Friesen M. D., Ravanat J.-L., Cadet J., Pignatelli B., Nishino H.Oshima H., J. Biol. Chem., 276, 40486 - 40496 (2001), "Chlorination of Guanosine and Other Nucleosides by Hypochlorous Acid and Myeloperoxidase of Activated Human Neutrophils"