8- Chloroadenosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer ( Sp-8-Cl-cAMPS )
C10H10ClN5O5PS•Na; MW 401.7; λmax 262 nm; ε 17000; sodium salt; purity > 99% HPLC. For other salt forms please inquire. Metabolically resistant activator of protein kinase A (cyclic AMP agonist). No metabolic side effects as observed with 8-Cl-cAMP (Cat. No. C 007) and significantly more lipophilic and membrane-permeant. Detailed technical information and updated reference list available on request. Reference: Yokozaki et al., Cancer Res., 52, 2504 - 2508 (1992); Beaver, et al., Nature Neurosci., 4, 159 - 163 (2001).
Protected under patent DE 3802865.4 exclusively licensed to BIOLOG LSI
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