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Alternative structural projections:


8- Chloroadenosine- 3', 5'- monophosphorothioate, Rp- isomer ( Rp-8-Cl-cAMPS ), sodium salt
Membrane-permeant analogue of the cyclic AMP antagonist Rp-cAMPS
Cat. No.: C 003
CAS No.: [142754-27-6]
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Product Name Price (net) Qty
Cat. No.: C 003-05
Unit: 5 µmol / ~2 mg
For other salt forms please inquire. Site-selective, competitive inhibitor of protein kinase A (cyclic AMP antagonist) with preference for type I of protein kinase A. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane-permeant compared to Rp-cAMPS. Detailed technical information and updated reference list available on request. Reference: Yokozaki et al., Cancer Res., 52, 2504 - 2508 (1992).
Cat. No. C 003
CAS number [142754-27-6]
Purity > 99% HPLC
Salt form Sodium
Storage temperature -20°C / -4°F
Molecular formula C₁₀H₁₀ClN₅O₅PS · Na
Molecular weight [g/mol] 401,7
cAMP modified at the exocyclic oxygen equatorial (Rp-)
Modifications 8-cAMP
Target PKA (cAK) Inhibitor
Lipophilicity 1.43
Absorption max [nm] 262
Molar extinction coefficient ε [L·mol⁻¹·cm⁻¹] 17000